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View Structure Prediction Details

Protein: YBP2
Organism: Saccharomyces cerevisiae
Length: 641 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YBP2.

Description E-value Query
Range
Subject
Range
YBP2_YEAST - YAP1-binding protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YBP2 PE=1 SV=1
YBP2 - Central kinetochore associated protein that mediates mitotic progression; interacts with several cen...
0.0 [1..641] [1..641]

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Predicted Domain #1
Region A:
Residues: [1-50]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYNEQVNSGK SIKEKERYLD ALLKILKDNP VTLKEIGWDL PKGLLQFFSR 

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [525-531]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQQNPGN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.77
Match: 1bgxT
Description: 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [51-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNINVNIHLV FSPLVSSVME CFNELAINGN PKECLLTACE LVSTLHIVLT E

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.77
Match: 1bgxT
Description: 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [102-293]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGDSDEENED LNDSNRNDAS NITDELSVIT PEIGHYMAKN TVEFIPNLKI YVLFEFMSLL  60
   61 LKRVDTLYPS KFLAMVTSAI IKYVTTNVQA MDDPHFILRI VYNFCTNYSP AQPSASLTDG 120
  121 ISTNDLEKIH DDESALQKKL LANLSVFVIS NCLKNHPGNI DKIYFKTLMH KKTDENEIDA 180
  181 SVLQICHQYY EY

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [347-524]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKKLADEKNL ELDQYGVVIL SAIHYSKNGT HLLPQIDIQS AIYLYLRCTT ASLFSEIYEN  60
   61 KFLESSVRYW LWVSTTETST EKIKCALQEL PGHITTAFLQ MLLMKTCNES NNDTKLTEIT 120
  121 LLRRLLYLMP ESTSFTFIFE TLLHCPYITA KIAVLDILRD MMIRSPEAAN RDETVGLI

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [532-641]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TANSVPIMPT LPPRPYITIN EDRMASIHSI ALICFSAAKQ KKRTQGDLLL VLTYMKFFVS  60
   61 LRNKWDLGLL TLINKEISES FQGEGEPELA FINISNNTLG EYIEEMNIRS 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.77
Match: 1bgxT
Description: 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [294-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTSLDVHMKE LLEKCLVESR SIYNSLLMNP AASTPEFKEE INQLVYEVSY AYQ

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.77
Match: 1bgxT
Description: 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [543-641]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPRPYITINE DRMASIHSIA LICFSAAKQK KRTQGDLLLV LTYMKFFVSL RNKWDLGLLT  60
   61 LINKEISESF QGEGEPELAF INISNNTLGE YIEEMNIRS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.828 a.24.17 Group V grass pollen allergen


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle