Protein Overview: PUG1

General Information:
Name(s) found:	PUG1 / YER185W [SGD]
Description(s) found: Found 25 descriptions. SHOW ALL	Plasma membrane protein with roles in the uptake of protoprophyrin IX and the efflux of heme; expression is induced under both low-heme and low-oxygen conditions; member of the fungal lipid-translocating exporter (LTE) family of proteins [SGD]
Organism:	Saccharomyces cerevisiae
Length:	303 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [ISS]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTTDSGFVL YHYTPSKAAA IVFVVLFIIM TVIFAVQTLY AARKSSKALK NNPFESSDDK  60
   61 VDSLEDAEYK QLKITPTVFA FIPFFTGCIM EAVGYIGRAL SSSNPERTTP YIIQSVLLLV 120
  121 APALIAATIY MIFGRLLHVM RCQSLILISA RFGTTFFVVG DVFSFFLQAA GGGLMSKAGS 180
  181 TKTGSGLITA GLFVQVIFFG FFIINEIRFT VNVKRRCLFY EDISRKWIFV NATLLLSSML 240
  241 ILLRSIVRIV EFIQGFNGYI ISHEYFIYVF DAVPMLLVII AFSVGSFFGN VFDVIKECQT 300
  301 LSN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	CEP3	sample cbf3 from feb 2005	Sandall S, et all (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	YJL147C	PUG1	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..170]	deduced	N/A	No confident structure predictions are available.
2	View Details	[171..303]	MSA	2.011973	View MSA. Confident ab initio structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2