YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: THO1

General Information:
Name(s) found: THO1 / YER063W [SGD]
Description(s) found:
Found 28 descriptions.
SHOW ALL
  • Conserved nuclear RNA-binding protein; specifically binds to transcribed chromatin in a THO- and RNA-dependent manner, genetically interacts with shuttling hnRNP NAB2; overproduction suppresses transcriptional defect caused by hpr1 mutation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 218 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: transcription, DNA-dependent [IGILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADYSSLTVV QLKDLLTKRN LSVGGLKNEL VQRLIKDDEE SKGESEVSPQ EQNQEQGSEP  60
   61 AAIEEPASQN ITEKKEVSSE PKETNEPKEE NKDVQKPSDG PSATASENEQ AAASTAAPAL 120
  121 SPEEIKAKAL DLLNKKLHRA NKFGQDQADI DSLQRQINRV EKFGVDLNSK LAEELGLVSR 180
  181 KNEPESGNNG KFKNRNKNAN NRSRVSKNRR GNRSGYRR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ALB1 ARX1 DBP9 GLE2 PSE1 RAD27 SLX9 THO1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data THO1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..55] Pfam 12.0 SAP domain No confident structure predictions are available.
    2 View Details [56..218] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle