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Protein Overview: YPS7

General Information:
Name(s) found: YPS7 / YDR349C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Putative GPI-anchored aspartic protease, located in the cytoplasm and endoplasmic reticulum [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 596 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: aspartic-type endopeptidase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTCLILWYLW LISTFQLEFA TASTANTTTT AKSGTSSSTE EPFPVLAVGK DGRGNYYVNS  60
   61 TFGTPGQRQR LLVDIIQPYI NLVSGTSESH NEYSGVYHKH PSYLMNDSTS SVPVSPGQIY 120
  121 EISFIDGRAV NCTLVTDDMN FTNVSSENSS TALITDLMVT RDNVQFNSGS LSISNVSFFD 180
  181 IQSSNFKTSG LLGLSGKVTN PGNAIDSSQY TEQSYFLSLL KDADIIESSS YSLWLAGDTS 240
  241 TYKTYRDPIS NCGKLLLGGV DPSLFTGTLG KFDLIPYVDP VSNAVSVGYP IVPLGPIYIV 300
  301 SNSGQSLNMT SKDFLSPALL DSTSSVSYLP TSTIIQIAVQ IAATYVESLD RWLVQCSIAD 360
  361 MGVSLGFRLR ELTIEIPLRD LLSSTYDTST NSSMFFSSGQ EACFLTLYAN TNTGVNILGE 420
  421 AFIKNIYMAM DLEDNTIAIA QAKKVEDDAV TEETNETTAS TIIKKIKSGY IPYAKVMNSS 480
  481 NTRNLTLYPS YRSGYMFTVP GQLTAAYSNG VITGAGRSFY DTSRASTSAR PSSTQFDSFS 540
  541 VSASEEWSNS TNRTSSASGA GVRLSSPYTF NKDPAGHVTR IASLLLLSIF SILIVL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) KEL2 SEN1 SSE2 YDR133C YPS7

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #20 Asynchronous Prep1-TiO2 Phosphopeptide enrichment, PartB Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YPS7 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..56]
    [227..514]    		 PSI-BLAST 150.491979 Acid protease
    2 View Details [57..226] PSI-BLAST 150.491979 Acid protease
    3 View Details [515..596] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  2.20821737779692 bayes_pls_golite062009
  • endopeptidase activity
    		•  2.15355609364204 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.06475762129734 bayes_pls_golite062009
  • catalytic activity
    		•  1.54514410489082 bayes_pls_golite062009
  • hydrolase activity
    		•  1.39298582879132 bayes_pls_golite062009
  • aspartic-type endopeptidase activity
    		•  1.26508476841498 bayes_pls_golite062009
  • aspartic-type peptidase activity
    		•  1.26508476841498 bayes_pls_golite062009
  • binding
    		•  0.507703606557062 bayes_pls_golite062009
  • protein binding
    		•  0.177729352622294 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle