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Protein Overview: SVF1

General Information:
Name(s) found: SVF1 / YDR346C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Protein with a potential role in cell survival pathways, required for the diauxic growth shift; expression in mammalian cells increases survival under conditions inducing apoptosis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 481 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: response to oxidative stress [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKWIKGGIS AVTGMAEPEY GKDYIHSVAD RVKNKQPYRE TSREDFFWQA PDHTNVESVI  60
   61 FYFSDLKTGI FGFAQVIHSN IIGLHTASQF TFRIFDSKNP EDLNIWTSTK LENFYIEGPN 120
  121 FYADNLSVEL SEDGESYHIQ SSVCDLSVVD LHIRRLTPGA KIGDDPATYY GNNINEPWGS 180
  181 MRHVFWPRNA CHGTIKVKKE VIPESDEEES SADEDDNEDE DEESGDSEEE SGSEEESDSE 240
  241 EVEITYEDRT ITFKEEDPAI STFIMAFQGM KPHHAAKAWN FMFFHSEKYS AVLMEFTTPK 300
  301 SYANTKISAG IITDDKEVLA MTTNNLVEHL NSEIDSVGWK VPKDIKITFK GINTKVKDEQ 360
  361 LESENGTEQA LQGEDEKEDE KEDEEEEEYK NVAEENKICA VVEGPLNNLV ERIDVMGEIP 420
  421 SFVKNIVSGV AGTKPFIYQY ADPKSSTLQI NGGEKIHGVA WTEVTFISES DVISEESYNE 480
  481 A

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CAR1 SVF1
    View Details Gavin AC, et al. (2006) KTR3 MRI1 SVF1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data SVF1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..203] MSA 1.004907 View MSA. No confident structure predictions are available.
    2 View Details [204..481] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.76

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle