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Protein Overview: SPR28

General Information:
Name(s) found: SPR28 / YDR218C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes; meiotic septin expressed at high levels during meiotic divisions and ascospore formation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 423 amino acids

    Gene Ontology:
    Cellular Component: cellular bud neck septin ring [TASLink to PubMed article]
    Biological Process: cell morphogenesis [TASLink to PubMed article]
    cellular cell wall organization [TASLink to PubMed article]
    Molecular Function: structural constituent of cytoskeleton [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFPMKDHSAL EQHTLSRDEL RRRKGYKKGL QLSILLLGEK GSGKSTFLNN LCGQDISLSD  60
   61 GDYDDDDDKV TNNVTPENGN AIEDIDPGYK TAHLSPGLKL VTRRVYLNDE LGVPITLDII 120
  121 LFPGCGDNVD NSQSSVVIKN YLDQQFANVL KEEVRIKRNT KETDGRPHVC LYFLKSTPRG 180
  181 VKKFDIELMK TICDKVNLIP IIPKADGLTE TELNLHKDIV RQEISQNNIR VFDFKSDTLG 240
  241 ETLALYDMDI DSSSAKSKYD NDTKIKEISP FAIVCSKTFN KNSENRVEHI RTYEWGSLVV 300
  301 EDQNTSDFIY LKAILLGSHL QELKDVTNNV LYENYRAKVL TEKKNNYDIP NYSYIDETSR 360
  361 GSVSNVSTRR NSASRTLGNP DTNDENAYQI HKEIDEKNRI IEDYQRKIDL LEKMLAAPHQ 420
  421 NKV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) CDC10 CDC11 CDC12 CDC3 SHS1 SPR28 SPR3
    View Details Qiu et al. (2008) CDC10 CDC11 CDC12 CDC3 SHS1 SPR28 SPR3

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CDC11 SPR28 2 Drees BL, et al. (2001)
    View Screen BEM4 SPR28 2 Drees BL, et al. (2001)
    View Screen TWF1 SPR28 1 Unpublished Fields Lab Data
    View Screen SPT21 SPR28 1 Unpublished Fields Lab Data
    View Screen APC5 SPR28 1 Unpublished Fields Lab Data
    View Screen PTC2 SPR28 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..246] ORFEUS 10.79 GTPase Era, N-terminal domain; GTPase Era C-terminal domain
    2 View Details [247..351] ORFEUS 10.79 GTPase Era, N-terminal domain; GTPase Era C-terminal domain
    3 View Details [352..423] MSA 5.076997 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle