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Protein Overview: VPS64

General Information:
Name(s) found: VPS64 / YDR200C [SGD]
Description(s) found:
Found 30 descriptions.
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  • Protein required for cytoplasm to vacuole targeting of proteins; forms a complex with Far3p and Far7p to Far11p involved in recovery from pheromone-induced cell cycle arrest; localizes to the cytoplasm and endoplasmic reticulum membrane [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 604 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: protein targeting to vacuole [IMPLink to PubMed article]
    cell cycle arrest in response to pheromone [IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVELEKRRRP PPQLQHSPYV RDQSNSQGMT KTPETSPPKR PMGRARSNSR SSGSRSNVDI  60
   61 DQYTIPPGLD LLPTASSPPS VHQVSQQQQL SPILANKIRS PFENQSQDQN DNSIDPTPAG 120
  121 QVTIPVEAVS PPALDELSKF QNGSTETLFR TGSPRKKHTH IIILKSLNAT FETKFLVVPF 180
  181 KPDGLKLGRP VTNSVNKNNS GSKRDLFSQQ VRPDNGNFDS RVLSRNHACL SCDPTSGKIY 240
  241 IRDLKSSNGT FVNGVKIRQN DVELKVGDTV DLGTDIDSKF EHRKISAYVE EISVIPLMNT 300
  301 VSDPTNLVMK KQDHTNKNNG NSTNINGIKI DRGHHNQHIP IRSHLKENYT EAGVTSATTA 360
  361 QRAAFEAAMF GDINNSELDD DILGPETEVL SGIFINNSAG TSINLINMIK TLTTELSLEK 420
  421 QELEKLHSMQ NFMQNYTINL DFINKHMIDM NEKHLLKLST ALQKTLSENN DALLKESEDQ 480
  481 LKEIKQQNNK VKSACSLKEK QNHEKLQELE SELRELNLQI EEERGKNLVL TQSNFNGGIN 540
  541 NDNNAKVKQN DSREEKKDTE DTLISTEELG VVEGKRTRVS KGMLFGVVAI SFGLVATAVK 600
  601 QLPQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) FAR7 FAR8 FET4 LSP1 PHO84 PIL1 VPS64

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen FAR10 VPS64 2 Uetz P, et al. (2000)
    View Screen FAR3 VPS64 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data VPS64 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..152] MSA 27.485997 View MSA. No confident structure predictions are available.
    2 View Details [153..219] deduced N/A Confident ab initio structure predictions are available.
    3 View Details [220..604] PSI-BLAST 19.69897 Heavy meromyosin subfragment


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.46

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle