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Protein Overview: CDC1

General Information:
Name(s) found: CDC1 / YDR182W [SGD]
Description(s) found:
Found 29 descriptions.
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  • Putative lipid phosphatase of the endoplasmic reticulum; shows Mn2+ dependence and may affect Ca2+ signaling; mutants display actin and general growth defects and pleiotropic defects in cell cycle progression and organelle distribution [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 491 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISSLink to PubMed article]
    Biological Process: DNA repair [IMPLink to PubMed article]
    cellular manganese ion homeostasis [IGILink to PubMed article][IMPLink to PubMed article]
    actin cytoskeleton organization [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVYRNRSKSV LSTHSKKSDD KAHYKSRSKK KSKSRSKKRL RIYWRYISIV WILWLGLISY  60
   61 YESVVVKRAM KKCQWSTWED WPEGAESHRV GLFADPQIMD EYSYPGRPQI VNYFTRVIVD 120
  121 HYHRRNWKYV QYYLDPDSNF FLGDLFDGGR NWDDKQWIKE YTRFNQIFPK KPLRRTVMSL 180
  181 PGNHDIGFGD TVVESSLQRF SSYFGETSSS LDAGNHTFVL LDTISLSDKT NPNVSRVPRQ 240
  241 FLDNFAMGSH PLPRILLTHV PLWRDPEQQT CGQLRESKEP FPIQKGHQYQ TVIENDISQE 300
  301 ILTKIQPEIL FSGDDHDHCQ ISHSYPFQGK TKNAQEITVK SCAMNMGISR PAIQLLSLYN 360
  361 PSDLTMVNAG GEYASKTYQT ELCYMPDPYK AIRMYLWGLL FSAAFIAYMH FFPKSFNNRV 420
  421 ATIMNRVFTR PDGNTSDLPL PTSISKSKSK KSLTHSKYAV NDTRSIKQFL VNAIVLFVSV 480
  481 MPIFIYFYTV V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data CDC1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..105]
    [147..202]    		 PSI-BLAST 45.154902 Purple acid phosphatase, N-terminal domain; Plant purple acid phosphatase, catalytic domain
    2 View Details [106..146]
    [203..361]    		 PSI-BLAST 45.154902 Purple acid phosphatase, N-terminal domain; Plant purple acid phosphatase, catalytic domain
    3 View Details [362..491] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle