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Protein Overview: TMS1

General Information:
Name(s) found: TMS1 / YDR105C [SGD]
Description(s) found:
Found 33 descriptions.
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  • Vacuolar membrane protein of unknown function that is conserved in mammals; predicted to contain eleven transmembrane helices; interacts with Pdr5p, a protein involved in multidrug resistance [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 473 amino acids

    Gene Ontology:
    Cellular Component: membrane [ISSLink to PubMed article]
    vacuolar membrane [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGAVISLPVS MAGSFVASCF GGCCSNLVTK TASSLGSSSL GTRLLYAVWL LLNSLISWVS  60
   61 YSANKSILWP GKTCTGTGEC GFFTVHRLNF ALGCLHLILA LVLTGVKSTN DVRAALQNSW 120
  121 WSLKFILYLC LIVLSFVIPN DFYIFFSKWV SVPSGAIFIL VGLILLVDFA HEWAETCISH 180
  181 VESEDEDSSF WQRFLVLGTT SMYTASIIMT VVMYVMFCHQ QCNMNQTAVT VNLILTVITL 240
  241 VLSVNPKIQE ANPKSGLAQS SMVSVYCTYL TMSAMSSEPD DKMCNPLVRS SGTRKFSIIL 300
  301 GSLFTFIAIA YTTTRAAANS AFQGTNTNGA IYLGNDIEYE GLGGQTRNQL RYEAIKQAVE 360
  361 EGSLPESALY DTAWLGTSSP TGAMDNQNDD ERTGTKYNYT LFHVIFFLAT QWIAILLTIN 420
  421 VTQDDVGDFI PVGRTYFYSW VKIVSAWICY ALYGWTVVAP AIMPDRFDYE NYY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data TMS1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..473] Pfam 283.387216 TMS membrane protein/tumour differentially expressed protein (TDE) No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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