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Protein Overview: GLE1

General Information:
Name(s) found: GLE1 / YDL207W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Cytoplasmic nucleoporin required for polyadenylated RNA export but not for protein import; component of Nup82p nuclear pore subcomplex; contains a nuclear export signal [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 538 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    nuclear pore [IDALink to PubMed article][TASLink to PubMed article]
    Biological Process: poly(A)+ mRNA export from nucleus [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFVFDEVFN SDTDSPEFEE TCSTTSSTSS QCPTPEPSPA IKLPSFTKVG TKKLVNESVV  60
   61 ILDPALENAL RDLNLQSKLI PINEPIVAAS SIIVPHSTNM PLPRASHSSL LDNAKNSNAT 120
  121 APLLEAIEES FQRKMQNLVL ANQKEIQSIR ENKRRVEEQR KRKEEEERKR KEAEEKAKRE 180
  181 QELLRQKKDE EERKRKEAEA KLAQQKQEEE RKKIEEQNEK ERQLKKEHEA KLLQQKDKLG 240
  241 KAVTNFDKIS KMFWHYKDKI AQIKQDIVLP IKKADVNVRN LLSRHKRKIN PKFGQLTNSN 300
  301 QQLFKIQNEL TQLINDTKGD SLAYHWILNF IAKAVVHQAE TEVRVKPESA LPLGKLTLYL 360
  361 LVQFPELQEL FMARLVKKCP FVIGFTCEID TEKGRQNMGW KRNNENKWED NTSYDERMGG 420
  421 ILSLFAIITR LQLPQEFITT TSHPFPIALS WHILARICNT PLNLITNTHF VILGSWWDAA 480
  481 AVQFLQAYGN QASKLLILIG EELTSRMAEK KYVGAARLRI LLEAWQNNNM ESFPEMSP

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) GLE1 NUP100 SUS1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data GLE1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..317] PSI-BLAST 23.522879 Heavy meromyosin subfragment
    2 View Details [318..538] deduced N/A No confident structure predictions are available.
    3 View Details [351..538] Pfam 55.39794 No description for PF07817.4 was found. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle