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View Structure Prediction Details

Protein: GLE1
Organism: Saccharomyces cerevisiae
Length: 538 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLE1.

Description E-value Query
Range
Subject
Range
GLE1 - Cytoplasmic nucleoporin required for polyadenylated RNA export but not for protein import; component...
GLE1_YEAST - Nucleoporin GLE1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GLE1 PE=1 SV=1
6.0E-75 [1..538] [1..538]
GLE1_MOUSE - Nucleoporin GLE1 OS=Mus musculus GN=Gle1 PE=1 SV=2
3.0E-51 [16..509] [153..659]
gi|119608210, gi... - gi|55665335|emb|CAH71064.1| GLE1 RNA export mediator homolog (yeast) [Homo sapiens], gi|55663119|emb...
1.0E-50 [16..509] [151..658]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
6.0E-46 [2..370] [213..587]
gi|45383668, gi|... - gi|9800486|gb|AAF99314.1|AF272033_1 fast myosin heavy chain isoform 2 [Gallus gallus], gi|45383668|r...
6.0E-46 [2..370] [1202..1576]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
1.0E-45 [2..370] [1196..1570]

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Predicted Domain #1
Region A:
Residues: [1-317]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFVFDEVFN SDTDSPEFEE TCSTTSSTSS QCPTPEPSPA IKLPSFTKVG TKKLVNESVV  60
   61 ILDPALENAL RDLNLQSKLI PINEPIVAAS SIIVPHSTNM PLPRASHSSL LDNAKNSNAT 120
  121 APLLEAIEES FQRKMQNLVL ANQKEIQSIR ENKRRVEEQR KRKEEEERKR KEAEEKAKRE 180
  181 QELLRQKKDE EERKRKEAEA KLAQQKQEEE RKKIEEQNEK ERQLKKEHEA KLLQQKDKLG 240
  241 KAVTNFDKIS KMFWHYKDKI AQIKQDIVLP IKKADVNVRN LLSRHKRKIN PKFGQLTNSN 300
  301 QQLFKIQNEL TQLINDT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.522879
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [318-538]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGDSLAYHWI LNFIAKAVVH QAETEVRVKP ESALPLGKLT LYLLVQFPEL QELFMARLVK  60
   61 KCPFVIGFTC EIDTEKGRQN MGWKRNNENK WEDNTSYDER MGGILSLFAI ITRLQLPQEF 120
  121 ITTTSHPFPI ALSWHILARI CNTPLNLITN THFVILGSWW DAAAVQFLQA YGNQASKLLI 180
  181 LIGEELTSRM AEKKYVGAAR LRILLEAWQN NNMESFPEMS P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [351-538]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPLGKLTLYL LVQFPELQEL FMARLVKKCP FVIGFTCEID TEKGRQNMGW KRNNENKWED  60
   61 NTSYDERMGG ILSLFAIITR LQLPQEFITT TSHPFPIALS WHILARICNT PLNLITNTHF 120
  121 VILGSWWDAA AVQFLQAYGN QASKLLILIG EELTSRMAEK KYVGAARLRI LLEAWQNNNM 180
  181 ESFPEMSP

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 55.39794
Match: PF07817.4
Description: No description for PF07817.4 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle