Protein Overview: YBR141C

General Information:
Name(s) found:	YBR141C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6319617\|ref\|NP_009699.1\| Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YBR141C is not an essential gene; Ybr141cp [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S46010 hypothetical protein YBR141c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|586549\|sp\|P38278.1\|YBZ1_YEAST RecName: Full=UPF0657 nucleolar protein YBR141C [NCBI NR] gi\|547577\|emb\|CAA55538.1\| YBR1118 [Saccharomyces cerevisiae] [NCBI NR] gi\|536440\|emb\|CAA85099.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] UPF0657 nucleolar protein YBR141C OS=Saccharomyces cerevisiae GN=YBR141C PE=1 SV=1 [Swiss-Prot] Protein of unknown function localised to nucleolus [mips] Putative S-adenosylmethionine-dependent methyltransferase; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YBR141C is not an essential gene [SGD] YBR141C, Chr II from 526983-527996, reverse complement [yeast_orfs2] Chr II from 526983-527996, reverse complement [yeastorf3.fasta] Chr II from 526982-527995, reverse complement [yeastorf4.fasta] Chr II from 527993-526980, reverse complement [yeastorf5.fasta] (P38278) Hypothetical 38.5 kDa protein in IRA1-MAK5 intergenic region [4932.FASTACCERV.txt] YBR141C SGDID:S0000345, Chr II from 527994-526981, reverse complement, Uncharacterized ORF [yeastflysequest.fasta] YBR141C SGDID:S0000345, Chr II from 528032-527019, reverse complement, Uncharacterized ORF [10112005cervSGD.fasta] Ybr141cp [Saccharomyces cerevisiae]gi\|547577\|emb\|CAA55538.1\| YBR1118 [Saccharomyces cerevisiae]gi\|536440\|emb\|CAA85099.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|626523\|pir\|\|S46010 hypothetical protein YBR141c - yeast (Saccharomyces cerevis [nrdb_11152004_Chlamydomonas] YBR141C SGDID:S000000345, Chr II from 528032-527019, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YBR141C is not an essential gene" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YBR141C SGDID:S000000345, Chr II from 528032-527019, reverse complement, Uncharacterized ORF, "Putative S-adenosylmethionine-dependent methyltransferase; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YBR141C is not an essentia [SGD_S-cerevisiae_na_05-08-2009_con_reversed.fasta] YBR1118 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Uncharacterized protein YBR141C [nr-271106-contam.fasta] Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YBR141C is not an essential gene; Ybr141cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] YBR141C SGDID:S000000345, Chr II from 528032-527019, reverse complement, Uncharacterized ORF, "Putative S-adenosylmethionine-dependent methyltransferase; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YBR141C is not an essential gene" [scerevisihumanrev.fasta] [chemostatdb.fasta]
Organism:	Saccharomyces cerevisiae
Length:	337 amino acids
Gene Ontology:
Cellular Component:	nucleolus [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSRKSKSIT GKRKQVGSNV TRVIKPQKTR RIIRRFHHLI NKRQSICKFL CLKENLDDSN  60
   61 EEKNDKIIRL SIKGNVRLGK YYEDGKSQSF NDAMESQLLR LHSLIKNESK SKDTSDLAVM 120
  121 YTLLGYIMNQ INKLGGLETY QIASQNGQLK ERGGDTSKLL EKWIRSSFEN CPGAVALEIG 180
  181 SLSSGNRISR CALFRNVVRI DLEEHEGVIK QDFMERPLPR NENDKFDLIS CSLVLNFVKN 240
  241 HRDRGAMCHR MVKFLKPQGY IFIVLPQACV THSRYCDKTL LQNLLGSIGL IMLNSHQSNK 300
  301 LYYCLYQLQV VSPQPSSFSK RIKVNDGPGL NNFGITL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#32 Asynchronous Prep-No Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	CTF8	YBR141C	1	Unpublished Fields Lab Data
View Screen	GRR1	YBR141C	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	YBR141C	Huh WK, et al. (2003)
View Data	YBR141C and NOP56	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..86]	deduced	N/A	No confident structure predictions are available.
2	View Details	[87..337]	MSA	1.002911	View MSA. No confident structure predictions are available.

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
transcription factor activity	3.18366984273735	bayes_pls_golite062009
methyltransferase activity	3.10667683620555	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	3.03092170856472	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	2.91374296950366	bayes_pls_golite062009
RNA methyltransferase activity	2.63941856307703	bayes_pls_golite062009
rRNA methyltransferase activity	2.14987271695676	bayes_pls_golite062009
transferase activity	1.97261773840408	bayes_pls_golite062009
sequence-specific DNA binding	1.67826024217505	bayes_pls_golite062009
transcription repressor activity	1.3964019208723	bayes_pls_golite062009
tRNA methyltransferase activity	1.38914410921124	bayes_pls_golite062009
catalytic activity	1.16970557486814	bayes_pls_golite062009
N-methyltransferase activity	1.13958114124635	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.01831614309793	bayes_pls_golite062009
transcription regulator activity	0.953292160159369	bayes_pls_golite062009
DNA binding	0.878229880745235	bayes_pls_golite062009
nucleic acid binding	0.861417215599224	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	0.596425215866866	bayes_pls_golite062009
protein methyltransferase activity	0.537387676293877	bayes_pls_golite062009
binding	0.486361285495359	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	0.374941249737739	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	0.300104233454652	bayes_pls_golite062009
rRNA (uridine) methyltransferase activity	0.129311242793576	bayes_pls_golite062009

No functions predicted.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2