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Protein Overview: EDS1

General Information:
Name(s) found: EDS1 / YBR033W [SGD]
Description(s) found:
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  • gi|6319507|ref|NP_009589.1| Putative zinc cluster protein; YBR033W is not an essential gene; Eds1p [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S45889 probable regulatory protein YBR033w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|586482|sp|P38073.1|EDS1_YEAST RecName: Full=Transcriptional regulatory protein EDS1; AltName: Full=Expression dependent on SLT2 protein 1 [NCBI NR]
  • gi|536248|emb|CAA84975.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|498760|emb|CAA53688.1| YBR0318 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1587589|prf||2206497M ORF YBR0318 [NCBI NR]
  • Uncharacterized transcriptional regulatory protein YBR033W OS=Saccharomyces cerevisiae GN=YBR033W PE=2 SV=1 [Swiss-Prot]
  • Transcriptional regulatory protein EDS1 OS=Saccharomyces cerevisiae GN=EDS1 PE=1 SV=1 [Swiss-Prot]
  • EDS1 Expression Dependent on Slt2 [mips]
  • Putative zinc cluster protein; YBR033W is not an essential gene [SGD]
  • YBR033W, Chr II from 301903-304662 [yeast_orfs2]
  • Chr II from 301903-304662 [yeastorf3.fasta]
  • (P38073) Putative 103.4 kDa transcriptional regulatory protein in RPL4A-HMT1 intergenic region [4932.FASTACCERV.txt]
  • EDS1 SGDID:S0000237, Chr II from 301906-304665, Uncharacterized ORF [yeastflysequest.fasta]
  • EDS1 SGDID:S0000237, Chr II from 301944-304703, Uncharacterized ORF [10112005cervSGD.fasta]
  • Eds1p [Saccharomyces cerevisiae]gi|536248|emb|CAA84975.1| unnamed protein product [Saccharomyces cerevisiae]gi|498760|emb|CAA53688.1| YBR0318 [Saccharomyces cerevisiae]gi|626834|pir||S45889 probable regulatory protein YBR033w - yeast (Saccharomyces cer [nrdb_11152004_Chlamydomonas]
  • YBR033W SGDID:S000000237, Chr II from 301944-304703, Uncharacterized ORF, "Non-essential protein of unknown function" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • EDS1 SGDID:S000000237, Chr II from 301944-304703, Uncharacterized ORF, "Putative zinc cluster protein; YBR033W is not an essential gene" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • YBR0318 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • ORF YBR0318 [nr-271106-contam.fasta]
  • Putative 103.4 kDa transcriptional regulatory protein in RPL4A-HMT1 intergenic region [nr-271106-contam.fasta]
  • Non-essential protein of unknown function; Eds1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Transcriptional regulatory protein EDS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EDS1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • EDS1 SGDID:S000000237, Chr II from 301944-304703, Genome Release 64-1-1, Uncharacterized ORF, "Putative zinc cluster protein; YBR033W is not an essential gene" [yeast-030211-contam.fasta]
  • EDS1 SGDID:S000000237, Chr II from 301944-304703, Genome Release 64-2-1, Uncharacterized ORF, "Putative zinc cluster protein, predicted to be a transcription factor; not an essential gene; EDS1 has a paralog, RGT1, that arose from the whole genome duplication" [20141208_orf_trans.fasta]
  • YBR033W SGDID:S000000237, Chr II from 301944-304703, Genome Release 64-1-1, Uncharacterized ORF, "Putative zinc cluster protein; YBR033W is not an essential gene" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 919 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHHVPNLYG TPIRDPHERK RNSASMGEVN QSVSSRNCER GSEKGTKQRK KASHACDQCR  60
   61 RKRIKCRFDK HTGVCQGCLE VGEKCQFIRV PLKRGPAKKR GSVVSIEKFS SDNDPLQYRP 120
  121 RTHSYPMNSG NNYLPSLARN SSFPSISSLF VPSITAQSQQ FVKVPYDDIK RRSSLAILGS 180
  181 DSSISTEFGG NYRLDENLNV RQEGKDIVAK GMITPVEEMG ACSSNVRRQG SQSLPIQEQR 240
  241 ASPYINPFIS GRSRLSSLSY TSEATTSEGN TQGKNQCMLT PNSVRSIEKE RLNSLTAGFP 300
  301 NKKLGTDGRS DKWDKNSTWK PVYRSSNPSH PSTEKNVSLN QEASAKPLML GTYRQFDATS 360
  361 FYKVLGIYYN FFHINFPVIP INKSKFTDML DPEKPNVIDE IRQINNEIIQ CFKTALEVLV 420
  421 FCKIKQRRSS KSTKSWSRDS LCDFQKGLYY IQNFNKCIAD CFQSLITIKP VLKQNSSVIP 480
  481 SRIKFIYFST IIVLNFILIL AGEESSLLLG PSVGVFNEFQ AHKLFLPFQN TSPMLLLNSN 540
  541 EESGDEILDY AVLFKRLYIL LNILDTLQSF RLGQPKLINL NFGSAIETYF SDKTGHNQVV 600
  601 EKAPVALDNI LRNLKLGEFI TYFVLNRKSL QVNVPHHLLF TNQTDYGEFA VEKGEHDNIA 660
  661 GKFETLLKKK EILIRKLLNI EQKNDHILEN CCNSDAEMKN IGELVCSMIT LVSGILDSIT 720
  721 NMNAENSVDL DSKPLPNAYF AQDSEEELMS PTQSITSNLA SEENTRCTTK DLMGTVSIFM 780
  781 LPMVEECYNI ISLIGPIPTT LISLYIRNGN MAKGINDRIM TLSTALNELV QITALFNTLE 840
  841 PFRKNAHDRA KRYYVSATSS TGCYESVMKS MYSGKCAASN ASNVAPSEEE NKKILKKFAD 900
  901 IGWKLMDDSE LGCCCCFFN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run KIP3 No Comments Cheeseman IM, et al. (2002)
    View Run SMC5 No Comments Hazbun TR, et al. (2003)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen MET18 EDS1 1 Unpublished Fields Lab Data
    View Screen SPO21 EDS1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..134] PSI-BLAST 8.69897 Hap1 (Cyp1); HAP1
    2 View Details [135..221] MSA 2.255996 View MSA. No confident structure predictions are available.
    3 View Details [222..393] MSA 8.233997 View MSA. No confident structure predictions are available.
    4 View Details [394..447] deduced N/A No confident structure predictions are available.
    5 View Details [448..807] ORFEUS 7.04 Histidine ammonia-lyase (HAL)
    6 View Details [808..919] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.625108569999163 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.297563906361978 bayes_pls_golite062009
  • DNA binding
    		•  0.187456195219132 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0382143741325586 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.60

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle