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Protein Overview: RKM3

General Information:
Name(s) found: RKM3 / YBR030W [SGD]
Description(s) found:
Found 30 descriptions.
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  • Ribosomal lysine methyltransferase specific for monomethylation of Rpl42ap and Rpl42bp (lysine 40); nuclear SET domain containing protein [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 552 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: phospholipid metabolic process [IGILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVTFKDDVH RILKFVANCN GRFEDSKCDI RESPLGGLGV FAKTDIAEGE SILTLNKSSI  60
   61 FSASNSSIAN LLCDSSIDGM LALNIAFIYE TTVFRNSSHW YPFLRTIRIR DDEGHLNLPP 120
  121 SFWHADAKRL LKGTSFDTLF DSLAPEEEIM EGFEIAVDLA HKWNDEFGLE IPKGFLDVSE 180
  181 ENHEEDYNLK LEKFISVAYT LSSRGFEIDA YHETALVPIA DLFNHHVSDP DLKFVSLYDV 240
  241 CDKCGEPDMC KHLIAEEYLE AENLDKNMPK VASMETRVID EDLIKSLEND LEKEYSNVTA 300
  301 NIEDDDGGIE NPDECVDLVL KNDVAQGQEI FNSYGELSNV FLLARYGFTV PENQYDIVHL 360
  361 GPDFMKILKK EEKYQEKVKW WSQVGHGLFS AWYAQMRQED EEDEDGQAKS DNLSDDIESE 420
  421 EEEEEEEGDD SLESWLSQLY IDSSGEPSPS TWALANLLTL TAVQWESLFS KKATPHISDS 480
  481 IVNEEKLPFL AKKDNPHSKK LLSNLLKEKQ LPCIKGDNSS KITSATKSML QNARTLVQSE 540
  541 HNILDRCLKR LS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) MAP1 RKM3
    View Details Krogan NJ, et al. (2006) MAP1 RKM3

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RKM3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..295] MSA 18.046997 View MSA. No confident structure predictions are available.
    2 View Details [296..399] MSA 2.028989 View MSA. No confident structure predictions are available.
    3 View Details [400..552] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • histone methyltransferase activity
    		•  6.20878333364554 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  6.08778683840554 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  5.45106430536252 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  5.45106430536252 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  5.45106430536252 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  3.98411678860954 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K9 specific)
    		•  3.54138873512018 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  2.69428385009711 bayes_pls_golite062009
  • methyltransferase activity
    		•  2.33114816345072 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  2.25175257044903 bayes_pls_golite062009
  • binding
    		•  1.67469558504376 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.29511015534184 bayes_pls_golite062009
  • protein binding
    		•  1.07532079834012 bayes_pls_golite062009
  • transferase activity
    		•  0.653108419761009 bayes_pls_golite062009
  • chromatin binding
    		•  0.628375771647179 bayes_pls_golite062009
  • catalytic activity
    		•  0.414641636618101 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle