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View Structure Prediction Details

Protein: RKM3
Organism: Saccharomyces cerevisiae
Length: 552 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RKM3.

Description E-value Query
Range
Subject
Range
RKM3_YEAST - Ribosomal lysine N-methyltransferase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=R...
RKM3 - Ribosomal lysine methyltransferase specific for monomethylation of Rpl42ap and Rpl42bp (lysine 40); ...
0.0 [1..552] [1..552]
RBCMT_ARATH - [Fructose-bisphosphate aldolase]-lysine N-methyltransferase, chloroplastic OS=Arabidopsis thaliana G...
4.0E-66 [1..327] [38..348]
SETD4 - SET domain containing 4
3.0E-64 [12..387] [36..333]
RBCMT_TOBAC - Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic OS=...
3.0E-63 [11..325] [56..355]
SETD4_MOUSE - SET domain-containing protein 4 OS=Mus musculus GN=Setd4 PE=2 SV=1
4.0E-63 [12..302] [35..302]
RBCMT_PEA - Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic OS=...
3.0E-62 [11..327] [53..354]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-61 [12..327] [56..356]

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Predicted Domain #1
Region A:
Residues: [1-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVTFKDDVH RILKFVANCN GRFEDSKCDI RESPLGGLGV FAKTDIAEGE SILTLNKSSI  60
   61 FSASNSSIAN LLCDSSIDGM LALNIAFIYE TTVFRNSSHW YPFLRTIRIR DDEGHLNLPP 120
  121 SFWHADAKRL LKGTSFDTLF DSLAPEEEIM EGFEIAVDLA HKWNDEFGLE IPKGFLDVSE 180
  181 ENHEEDYNLK LEKFISVAYT LSSRGFEIDA YHETALVPIA DLFNHHVSDP DLKFVSLYDV 240
  241 CDKCGEPDMC KHLIAEEYLE AENLDKNMPK VASMETRVID EDLIKSLEND LEKEY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
histone methyltransferase activity 6.20878333364554 bayes_pls_golite062009
protein methyltransferase activity 6.08778683840554 bayes_pls_golite062009
lysine N-methyltransferase activity 5.45106430536252 bayes_pls_golite062009
protein-lysine N-methyltransferase activity 5.45106430536252 bayes_pls_golite062009
histone-lysine N-methyltransferase activity 5.45106430536252 bayes_pls_golite062009
N-methyltransferase activity 3.98411678860954 bayes_pls_golite062009
histone methyltransferase activity (H3-K9 specific) 3.54138873512018 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 2.69428385009711 bayes_pls_golite062009
methyltransferase activity 2.33114816345072 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 2.25175257044903 bayes_pls_golite062009
binding 1.67469558504376 bayes_pls_golite062009
nucleic acid binding 1.29511015534184 bayes_pls_golite062009
protein binding 1.07532079834012 bayes_pls_golite062009
transferase activity 0.653108419761009 bayes_pls_golite062009
chromatin binding 0.628375771647179 bayes_pls_golite062009
catalytic activity 0.414641636618101 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [296-399]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNVTANIEDD DGGIENPDEC VDLVLKNDVA QGQEIFNSYG ELSNVFLLAR YGFTVPENQY  60
   61 DIVHLGPDFM KILKKEEKYQ EKVKWWSQVG HGLFSAWYAQ MRQE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [400-552]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEEDEDGQAK SDNLSDDIES EEEEEEEEGD DSLESWLSQL YIDSSGEPSP STWALANLLT  60
   61 LTAVQWESLF SKKATPHISD SIVNEEKLPF LAKKDNPHSK KLLSNLLKEK QLPCIKGDNS 120
  121 SKITSATKSM LQNARTLVQS EHNILDRCLK RLS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle