Protein Overview: SIR2_RAT

General Information:
Name(s) found:	SIR2_RAT [Swiss-Prot]
Description(s) found: Found 12 descriptions. SHOW ALL	NAD-dependent protein deacetylase sirtuin-2 OS=Rattus norvegicus GN=Sirt2 PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	350 amino acids
Gene Ontology:
Cellular Component:	cytoskeleton [IEA] cytoplasm [UNKNOWN][ISS] cellular_component [ND] microtubule [UNKNOWN][IEA]
Biological Process:	cell division [IEA] biological_process [ND] negative regulation of transcription [UNKNOWN] protein amino acid deacetylation [UNKNOWN][IEA] mitosis [IEA] chromatin silencing [IEA] regulation of transcription [IEA] cell cycle [IEA] negative regulation of striated muscle tissue development [UNKNOWN]
Molecular Function:	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [IEA] zinc ion binding [UNKNOWN][IEA] histone acetyltransferase binding [UNKNOWN] histone deacetylase binding [UNKNOWN] tubulin deacetylase activity [UNKNOWN] transcription factor binding [UNKNOWN] molecular_function [ND] protein binding [UNKNOWN] ubiquitin binding [UNKNOWN] metal ion binding [IEA] NAD-dependent histone deacetylase activity [UNKNOWN] protein deacetylase activity [UNKNOWN] NAD binding [IEA] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFLRNLFTQ TLGLGSQKER LLDELTLEGV TRYMQSERCR RVICLVGAGI STSAGIPDFR  60
   61 SPSTGLYANL EKYHLPYPEA IFEISYFKKH PEPFFALAKE LYPGQFKPTI CHYFIRLLKE 120
  121 KGLLLRCYTQ NIDTLERVAG LEPQDLVEAH GTFYTSHCVN TSCGKEYTMS WMKEKIFSEA 180
  181 TPKCEKCQNV VKPDIVFFGE NLPPRFFSCM QSDFSKVDLL IIMGTSLQVQ PFASLISKAP 240
  241 LATPRLLINK EKTGQTDPFL GMMMGLGGGM DFDSKKAYRD VAWLGDCDQG CLALADLLGW 300
  301 KELEDLVRRE HANIDAQSGS QASNPSATVS PRKSPPPAKE AARTKEKEEH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.75

Protein Overview: SIR2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: