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Protein Overview: seq-PA

General Information:
Name(s) found: seq-PA / FBpp0099939 [FlyBase]
Description(s) found:
Found 16 descriptions.
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  • The gene sequoia is referred to in FlyBase by the symbol Dmel\seq (CG32904, FBgn0028991). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9067187..9077579. It has the cytological map location 49F4-49F7. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. There is experimental evidence that it is involved in the biological process</span>: negative regulation of axon extension; sensory organ development; dendrite morphogenesis; axonogenesis. 15 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 882 amino acids

    Gene Ontology:
    Cellular Component: nucleus [TAS]
    intracellular [IEA]
    Biological Process: negative regulation of axon extension [IMP]
    axonogenesis [IMP]
    sensory organ development [IMP]
    dendrite morphogenesis [IMP][TAS]
    Molecular Function: zinc ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQQSRKFEGK IPKLSQTSAA TGGATAAAEA STSKSSQGQQ QQIVYVNMLP AANTLNGIPQ  60
   61 QQQQQQYAST DGNVYQLQNE ILCDANGHAV TAATASYQTT ASSPQQQQQQ QQQQQNVATS 120
  121 VADNVVTTIS SSSILHTNAN TNGVDTLAAT QQQQQQQQQQ QQQQQQQHYH YITTTGEDGQ 180
  181 TPTTIVFENY NGGMPAVSSA APTPVPVSQA NAPATTTTTA LVNTDGTIIE FDGSTYEEYH 240
  241 VLKSEPGSSD CLSNGSSAVA ADIIKYDPQH GVVGDEEDDD ENGMLHVKYE EQSLEHDPEN 300
  301 EHDAEQEHEY EEYQVIKAEV EAEAAELAAG TTSYTISQEQ TGSGNTVLSS MVPKSGSAAA 360
  361 AKQKRKRKTR VIADDEQGEY LEKMSVRGLD IARYEHIIDG VAYCLVCAKN DIFKTFKNKY 420
  421 SFQRHAYLFH EGQNRKIFAC PICNKEFSRP DKMKMHKKDK HGDVPMPPSA TTTPLKADGP 480
  481 PAKRARTART PRVRKTKDGS TPTKKRLAQI DSVLDDVQNG ESLTMAPVSV SHSQQQQQQQ 540
  541 IQHSITTLAP STPSQPQHQL QTLPSLDFSG MILPGGAQLA LANPGATSSV GLQRGPATPN 600
  601 GQPAPPTTTL IYSNQLELQQ ALLQQQLQGQ SIMIQDQAGN LVPLQLDGTQ AIYTTAPQAQ 660
  661 RQQTTATYQT TQQQQQQPAQ QPAGQAQQQP HYELDNVTYL SSTAAATPTS AEQQQQQQQQ 720
  721 QHVIGTVQSY QILTPDGLQN FQPKLETAEL GDLCPYSQYT FTTHAGAQPT LNANALDAQT 780
  781 QHQQHHQQQQ HHHQQQQHHQ QTQLLQQQPF ATHHNPHQQF MELKNELLIK GGDAYTLDTA 840
  841 SMYHLPFSPT SMINAVNDVN TSSLLETKEI SYDISEAVLL AL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..212] deduced N/A No confident structure predictions are available.
    2 View Details [213..348] deduced N/A No confident structure predictions are available.
    3 View Details [349..447] PSI-BLAST 18.522879 No description for 2dlqA was found.
    4 View Details [448..602] PSI-BLAST 56.69897 No description for 2i13A was found.
    5 View Details [603..808] MSA 1.118995 View MSA. No confident structure predictions are available.
    6 View Details [809..882] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  3.10743787485868 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.9286072149962 bayes_pls_golite062009
  • DNA binding
    		•  2.91902554182176 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.84809232393523 bayes_pls_golite062009
  • transcription factor activity
    		•  2.01262882344347 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.81101516804605 bayes_pls_golite062009
  • chromatin binding
    		•  1.30226466791538 bayes_pls_golite062009
  • transcription factor binding
    		•  1.1783268121342 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.11260773303318 bayes_pls_golite062009
  • transcription activator activity
    		•  1.10770079514261 bayes_pls_golite062009
  • protein binding
    		•  1.00484935878505 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.42806308573128 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.18282984873138 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0300220090535304 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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