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Protein Overview: kay-PD

General Information:
Name(s) found: kay-PD / FBpp0099941 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene kayak is referred to in FlyBase by the symbol Dmel\kay (CG33956, FBgn0001297). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25592497..25619838. It has the cytological map location 99B10-99C1. There is experimental evidence that it has the molecular function</span>: protein binding; sequence-specific DNA binding; RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: anatomical structure development; sensory organ development; organ development; reproductive process in a multicellular organism; response to stress; cell cycle; cellular component movement; response to external stimulus; organ morphogenesis; ovarian follicle cell development. 45 alleles are reported. The phenotypes of these alleles are annotated with 42 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; nervous system; external compound sense organ; embryonic nervous system; peripheral nervous system; multi-cell-component structure; imaginal precursor; embryonic heart; dorsal thoracic disc; primordium; adult midgut precursor; adult cuticle; cephalopharyngeal skeleton; commissure; neuromuscular junction. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 722 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][NAS]
    cytoplasm [IDA]
    Biological Process: dorsal closure [IMP][NAS][TAS]
    wing disc development [IMP]
    imaginal disc fusion, thorax closure [IMP][TAS]
    midgut development [IMP]
    ovarian follicle cell migration [IMP]
    response to wounding [IMP]
    head involution [IMP]
    regulation of transcription, DNA-dependent [IEA]
    JNK cascade [NAS]
    border follicle cell migration [IGI]
    R3/R4 cell fate commitment [IMP][TAS]
    compound eye development [IMP]
    wound healing [IMP]
    central nervous system development [IMP]
    establishment of planar polarity [NAS]
    second mitotic wave during compound eye morphogenesis [IMP]
    regulation of cyclin-dependent protein kinase activity involved in G2/M [IMP]
    antimicrobial humoral response [IMP]
    Molecular Function: DNA binding [IDA]
    transcription factor activity [IEA][TAS]
    protein binding [IPI]
    RNA polymerase II transcription factor activity [IDA]
    protein heterodimerization activity [ISS]
    specific RNA polymerase II transcription factor activity [NAS]
    protein dimerization activity [IEA]
    sequence-specific DNA binding [IDA]
    transcription factor binding [NAS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIALKATEMQ HNNNALQQQQ QLQHQLLQQH QQQHQQQLQQ QLNSPDNNYI WATTHNANIS  60
   61 RNNAMLQLQQ QQLRAPWITD CNKQHHINNN NSMNVNYNQQ LTQQPQQQQQ QTQYMQHNYN 120
  121 NYTQQQQQQH LVPATTSQSN SHFYQCNQQQ QQQQFLAPTT TTAAVVVAAA HQQHQTQQQH 180
  181 QSQQQQQHQR QDYASLQMGR QLGNFETGQS VLTLTTPTLT PTTTRNIEDT LGHLLSDTQT 240
  241 DRVAGCAGFA VPKVLPNAID VLGMGIPTGV SSLPLQQTFD LSLGQGSESE DSNASYNDTQ 300
  301 MNEEQDTTDT SSAHTDSTSY QAGHIMAGSV NGGGVNNFSN VLAAVSSSRG SASVGSSNAN 360
  361 TSNTPARRGG GRRPNRSTNM TPEEEQKRAV RRERNKQAAA RCRKRRVDQT NELTEEVEQL 420
  421 EKRGESMRKE IEVLTNSKNQ LEYLLATHRA TCQKIRSDML SVVTCNGLIA PAGLLSAGSS 480
  481 GSGASSHHNH NSNDSSNGTI TGMDATLNST GRSNSPLDLK PAANIDSLLM HIKDEPLDGA 540
  541 IDSGSSLDQD GPPPSKRITL PPMSTMPHVH LSTILTPTGA SSGSLQTPIT STAPGGFGSA 600
  601 FPVTSNGSSI NNINSIGNNM NSPTLNAHNK VPKERPNTLA FQRPLGQMHL TMANNKAGGP 660
  661 TQIQGVPIQT PSTGTFNFDS LMDGGTGLTP VSGPLVPNSS STNKHPLELP TPTAEPSKLV 720
  721 SL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..203] MSA 9.114996 View MSA. No confident structure predictions are available.
    2 View Details [204..379] deduced N/A No confident structure predictions are available.
    3 View Details [380..460] PSI-BLAST 16.0 C-fos
    4 View Details [461..597] FFAS03 0.962 No description for 2jn4A was found.
    5 View Details [598..722] MSA 3.081997 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle