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Protein Overview: CG7220-PE, CG722...

General Information:
Name(s) found: FBpp0308551 [FlyBase]
CG7220-PE / FBpp0111977 [FlyBase]
CG7220-PB / FBpp0087313 [FlyBase]
Description(s) found:
Found 29 descriptions.
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  • type=protein; loc=2R:join(6623429..6623560,6624162..6624253,6624398..6624500,6624565..6624796,6624862..6624875); ID=FBpp0308551; name=CG7220-PF; parent=FBgn0033544,FBtr0339465; dbxref=FlyBase:FBpp0308551,FlyBase_Annotation_IDs:CG7220-PF; MD5=3103b0ffaa60cd4e3235cae76687d262; length=190; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG7220 (CG7220, FBgn0033544). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6618861..6626116. It has the cytological map location 47B7-47B9. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquitin-protein ligase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: proteolysis. 9 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG7220 (CG7220, FBgn0033544). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6618861..6626116. It has the cytological map location 47B7-47B9. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquitin-protein ligase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: proteolysis. 9 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 190 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: regulation of protein metabolic process [IEA]
    proteolysis [ISS]
    post-translational protein modification [IEA]
    Molecular Function: ubiquitin-protein ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMKLFKKPKD KIPKSEILTE PKEPKTPPVS KCGKPLQLDN SRWERRLHKE LMSLIKEPPP  60
   61 GVTIDTESVQ QNLSEWKINI KGFEGTLYEG EDFQLLFKFN NKYPFDSPEV TFIGTNIPVH 120
  121 PHVYSNGHIC LSILTEDWSP ALSVQSVCLS IASMLSSCRE KKRPPDNTIY VKTCNKNPKK 180
  181 TKWWYHDDSV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..190] PSI-BLAST 24.39794 Structure of the human hypothetical ubiquitin-conjugating enzyme, LOC55284

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • small conjugating protein ligase activity
    		•  6.80727357703118 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  6.75330204125607 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  5.83782824833863 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  4.30935997378918 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.21355731489173 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.13970605403492 bayes_pls_golite062009
  • DNA binding
    		•  1.95596447916631 bayes_pls_golite062009
  • binding
    		•  1.75350658654805 bayes_pls_golite062009
  • ligase activity
    		•  1.68348064141866 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.5236035191291 bayes_pls_golite062009
  • catalytic activity
    		•  0.891402822028799 bayes_pls_golite062009
  • SUMO ligase activity
    		•  0.843488104298821 bayes_pls_golite062009
  • protein binding
    		•  0.726328463755484 bayes_pls_golite062009
  • NEDD8 ligase activity
    		•  0.715654744941217 bayes_pls_golite062009
  • protein kinase activity
    		•  0.443948654247666 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.182854082413338 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.122859425935324 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0501858755083694 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.0234849623298925 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0138208971172455 bayes_pls_golite062009
  • transcription factor binding
    		•  0.0104967529560147 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle