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Protein Overview: glt-4

General Information:
Name(s) found: glt-4 / CE38553 [WormBase]
Description(s) found:
Found 16 descriptions.
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  • WBGene00001622 locus:glt-4 Putative sodium-dependent excitatory amino acid transporter glt-4 status:Partially_confirmed UniProt:Q22682 protein_id:CCD72844.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 499 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: dicarboxylic acid transport [IEALink to PubMed article]
    phosphate transport [IEALink to PubMed article]
    Molecular Function: inorganic phosphate transmembrane transporter activity [IEALink to PubMed article]
    sodium:dicarboxylate symporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKLSKENLL LLFTVLGVVV GIGLGFSLRD PSKAWSKRHL SYLRFPGDLF VQMLKMLILP  60
   61 MIMSSIITSL ASLDSGTAGR LGMVSMIYYT LTTFFAVFLG IVLVSVIKPG KWTTTNIEDL 120
  121 VGHVKTTPCV ATAVDTIIDL MKSCFPENLI EATFRSQKIC LKFFNGTTEI PPEIAMTMSP 180
  181 EQRAQFTEVP EKIVSDGMNI LGLVVFSVAL GIVIGVIGED GKPMKNFFKS LEACSMKLIG 240
  241 WVIIYSPVGI TFLIAAQIVG MKDPGQELHR LMGYVITVIL GLLIHAFVVI PLLCVVLARR 300
  301 NPIKFVGGMA QALLTALATS SSSATLPLSI KCCEENNKVD PRVTRFVLPL GATINMDGTA 360
  361 LYEAVAAIYI SQCYGNDLSL GEVVLVSLTA TLASIGAAGI PQAGIVTMIM VLIAIGLPTN 420
  421 LFILIFPVDF MLDRLRTTVN VHGDSIATAV IERLCEDQLQ KGGHHLDTND QGYSMLSTNA 480
  481 SPDPKRITIG NNCENSHML

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..499] PSI-BLAST 75.30103 Structure of glutamate transporter homolog from Pyrococcus horikoshii

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • high-affinity glutamate transmembrane transporter activity
    		•  9.03564241021137 bayes_pls_golite062009
  • dicarboxylic acid transmembrane transporter activity
    		•  8.28237742051097 bayes_pls_golite062009
  • L-aspartate transmembrane transporter activity
    		•  6.32804156021168 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  6.20769381184606 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  6.19258658226115 bayes_pls_golite062009
  • transporter activity
    		•  5.14616859489508 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  5.08516306839475 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  5.06400974103865 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  5.03536308870823 bayes_pls_golite062009
  • anion:cation symporter activity
    		•  4.98731042525142 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.56245375639148 bayes_pls_golite062009
  • L-glutamate transmembrane transporter activity
    		•  4.55490142908046 bayes_pls_golite062009
  • acidic amino acid transmembrane transporter activity
    		•  4.55490142908046 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.38524103588396 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  4.37939766329509 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  3.93820513423101 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  3.7335977004076 bayes_pls_golite062009
  • L-amino acid transmembrane transporter activity
    		•  3.55306444119183 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  3.47181854698038 bayes_pls_golite062009
  • symporter activity
    		•  3.47181854698038 bayes_pls_golite062009
  • organic acid:sodium symporter activity
    		•  3.44677545809568 bayes_pls_golite062009
  • amino acid transmembrane transporter activity
    		•  3.22640982674356 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  3.11518167297447 bayes_pls_golite062009
  • C4-dicarboxylate transmembrane transporter activity
    		•  2.522484225611 bayes_pls_golite062009
  • L-cystine transmembrane transporter activity
    		•  2.23126735245762 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  2.02127810434029 bayes_pls_golite062009
  • solute:sodium symporter activity
    		•  1.76557983021416 bayes_pls_golite062009
  • protein binding
    		•  1.39188421476117 bayes_pls_golite062009
  • binding
    		•  1.33552537079117 bayes_pls_golite062009
  • L-threonine transmembrane transporter activity
    		•  1.13816899539559 bayes_pls_golite062009
  • L-serine transmembrane transporter activity
    		•  1.13816899539559 bayes_pls_golite062009
  • L-proline transmembrane transporter activity
    		•  1.13816899539559 bayes_pls_golite062009
  • L-alanine transmembrane transporter activity
    		•  1.13816899539559 bayes_pls_golite062009
  • serine transmembrane transporter activity
    		•  1.13816899539559 bayes_pls_golite062009
  • L-hydroxyproline transmembrane transporter activity
    		•  1.13816899539559 bayes_pls_golite062009
  • alanine transmembrane transporter activity
    		•  1.13816899539559 bayes_pls_golite062009
  • amino acid binding
    		•  1.0487791191866 bayes_pls_golite062009
  • cation:amino acid symporter activity
    		•  0.85052491897986 bayes_pls_golite062009
  • sulfur amino acid transmembrane transporter activity
    		•  0.791452273778402 bayes_pls_golite062009
  • amine binding
    		•  0.621133377213499 bayes_pls_golite062009
  • glutamate:sodium symporter activity
    		•  0.553718735358201 bayes_pls_golite062009
  • neutral amino acid transmembrane transporter activity
    		•  0.444280550441749 bayes_pls_golite062009
  • monocarboxylic acid transmembrane transporter activity
    		•  0.31624582149961 bayes_pls_golite062009
  • neurotransmitter transporter activity
    		•  0.25304246415333 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.119412711778045 bayes_pls_golite062009
  • channel activity
    		•  0.119412711778045 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.0999184515491418 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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