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Catalysis of the transfer of isopropylmalate from one side of the membrane to the other. Catalysis of the transfer of oxaloacetate, the anion of oxobutanedioic acid, from one side of the membrane to the other. Catalysis of the transfer of dicarboxylic acids from one side of the membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups. Catalysis of the transfer of tartrate from one side of the membrane to the other. Tartrate is the anion of 2,3-dihydroxybutanedioic acid, one of the aldaric acids. The L(+) enantiomer occurs widely in plants, especially in grape juice, and in fungi and bacteria. Catalysis of the transfer of oxalate from one side of the membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals. Catalysis of the transfer of carboxylic acids from one side of the membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). Catalysis of the transfer of alpha-ketoglutarate from one side of the membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle. Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). Catalysis of the transfer of fumarate from one side of the membrane to the other. Fumarate is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate. Catalysis of the transfer of C4-dicarboxylate from one side of the membrane to the other. Catalysis of the transfer of organic acids, any acidic compound containing carbon in covalent linkage, from one side of the membrane to the other.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: dicarboxylic acid transmembrane transporter activity
Acc: GO:0005310
Aspect: Molecular Function
Desc: Catalysis of the transfer of dicarboxylic acids from one side of the membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.
Synonyms:
  • GO:0015365
  • sodium:dicarboxylate/tricarboxylate symporter activity
  • dicarboxylate carrier
  • GO:0005312
  • dicarboxylic acid permease activity
  • dicarboxylate (succinate/fumarate/malate) antiporter activity
Proteins in PDR annotated with:
   This term: 17 [Search]
   Term or descendants: 195 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005310 - dicarboxylic acid transmembrane transporter activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle