Protein Overview: alh-3

General Information:
Name(s) found:	alh-3 / CE40358 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00000109 locus:alh-3 status:Confirmed UniProt:G5ECV9 protein_id:CAA92998.2 [WormBase] gi\|133930964\|ref\|NP_502054.2\| ALdehyde deHydrogenase family member (alh-3) [Caenorhabditis elegans] [NCBI NR] gi\|112982607\|emb\|CAA92998.2\| C. elegans protein F36H1.6, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|112982606\|emb\|CAA92957.2\| C. elegans protein F36H1.6, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] [wormpep130-phg-ecoli-orf-rand.fasta] CE40358 WBGene00000109 locus:alh-3 formyltetrahydrofolate dehydrogenase status:Confirmed UniProt:Q19428_CAEEL protein_id:CAA92998.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] [wormORF-contam.fasta] CE40358 WBGene00000109 locus:alh-3 formyltetrahydrofolate dehydrogenase status:Confirmed UniProt:Q19428_CAEEL protein_id:CAA92998.2\| [wormORF-contam.fasta] Hypothetical protein F36H1.6 [Caenorhabditis elegans] [nr-271106-contam.fasta] CE40358 WBGene00000109 locus:alh-3 formyltetrahydrofolate dehydrogenase status:Confirmed TR:Q19428 protein_id:CAA92998.2 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta] CE40358 WBGene00000109 locus:alh-3 formyltetrahydrofolate dehydrogenase status:Confirmed UniProt:Q19428 protein_id:CAA92998.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] CE40358 WBGene00000109 locus:alh-3 formyltetrahydrofolate dehydrogenase status:Confirmed UniProt:G5ECV9 protein_id:CAA92998.2 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE40358 WBGene00000109 locus:alh-3 status:Confirmed UniProt:G5ECV9 protein_id:CAA92998.2 Aldehyde dehydrogenase [wormpep246-ecoli-contam.fasta] CE40358 WBGene00000109 locus:alh-3 status:Confirmed UniProt:G5ECV9 protein_id:CAA92998.2 10-formyltetrahydrofolate dehydrogenase [c_elegans-PRJNA13758-WS250-ecoli-contam.fasta] 10-formyltetrahydrofolate dehydrogenase OS=Caenorhabditis elegans GN=alh-3 PE=1 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	908 amino acids
Gene Ontology:
Cellular Component:	mitochondrial matrix [IEA] cytoplasm [IEA]
Biological Process:	cellular aldehyde metabolic process [IEA] proline metabolic process [IEA] negative regulation of transcription [IEA] metabolic process [IEA] 'de novo' IMP biosynthetic process [IEA] 10-formyltetrahydrofolate catabolic process [IEA] proline biosynthetic process [IEA] biosynthetic process [IEA] valine metabolic process [IEA] betaine biosynthetic process [IEA] one-carbon metabolic process [IEA] translation [IEA]
Molecular Function:	aldehyde dehydrogenase [NAD(P)+] activity [IEA] methylmalonate-semialdehyde dehydrogenase (acylating) activity [IEA] methyltransferase activity [IEA] phosphoribosylglycinamide formyltransferase activity [IEA] methionyl-tRNA formyltransferase activity [IEA] 1-pyrroline-5-carboxylate dehydrogenase activity [IEA] DNA binding [IEA] betaine-aldehyde dehydrogenase activity [IEA] proline dehydrogenase activity [IEA] oxidoreductase activity [IEA] cofactor binding [IEA] formyltetrahydrofolate dehydrogenase activity [IEA] transcription repressor activity [IEA] oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [IEA] hydroxymethyl-, formyl- and related transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIAIIGQSA FGVDVYKELR KNGHEIVVVF TIPDKNGRED LLAVEAAKDG VPVQKPSRWR  60
   61 KKNPETGKFE TLPEMLELYK SFGAELNVLP FCTQFIPLEI TEAPAKKSII YHPSILPKHR 120
  121 GASAINWTLI EGDEEAGLSI FWADDGLDTG PILLQKKCKV EENDTLNTLY KRFLYPAGVA 180
  181 AVAESVELIA TGKAPRIVQP EEGASYEPYI TTKPELAQID WSKTQRQLHN FIRGNDKVPG 240
  241 AWAVLNGEKV SFFGSKLWKP KKLPDDAVEV FVSEVPGGKV LVEDRGLLLP GSDGRWVIVD 300
  301 TVKIGTKTVP ASKYGQGADQ VQELVLTDEE KSTVAKLKKI WTGILKTQVS SDTDFFESGA 360
  361 SSADVTRLVE EIKFNTGAEL ESGQIYAGPT LGENIDIVIR NLRGEGGISV TYDPIVLNVN 420
  421 NMELKFPHDQ FIDGKFVGSS DGRTFKTINP ATEKPICELP LATVADVDRA VRAAKKAFER 480
  481 GEWRQMSARE RGKRLYKLAE LMEEHKEELA TLESLDAGAV YTLALKTHVG MSIDVWRYFA 540
  541 GWCDKIQGKT IPISNARPNK NLCLTLREPI GVVGLITPWN YPLMMLSWKM AACLAAGNTV 600
  601 VHKPAQVTPL TALKFAELSV LAGIPPGVIN IVTGSGSLVG NRLTAHPDVR KIGFTGSTEI 660
  661 GATVMESCAK SNIKKVSLEL GGKSPLIIFA DADLEKAVKQ ACGAVFFNKG ENCIAAGRVF 720
  721 IAKSIHDDFV KKLVEEAKQY QIGDPLDRST AHGPQNHLAH LNKLVEYVEK AVAGGAKVEV 780
  781 GGKRLEREGL YFPPTILSNI DDENFAASEE SFGPIMCVSS FDDDDIEDVL RRANDTEFGL 840
  841 AAGVFTRDSS KSLRVAEALH AGTVFVNTYQ KTDVAAPFGG FKQSGFGKDM GEEALNEYLV 900
  901 TKTITIEY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: alh-3

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: