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Protein Overview: gi|25301089

General Information:
Name(s) found: gi|25301089 [NCBI NR]
Description(s) found:
Found 2 descriptions.
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  • pir||AD0432 aerobic respiration control sensor/response regulatory protein (EC 2.7.3.-) [imported] - Yersinia pestis (strain CO92) [NCBI NR]
    • Organism: Yersinia pestis
    Length: 778 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQIRVLAQY YVDLMVKLGL VRFSLLLASA LVLLAMVVQM AVTFVLRGSV ETLDLVRSIF  60
   61 FGLLITPWAV YFLSVVVEQL EESRQRLSRL VDKLEVMRHR DLELNKQLTE NITQLNQEIV 120
  121 EREKAEKAHL QVVDKLKEEM GHREQAQIEL GQQSALLRSF LDASPDLVYY RNEDNEFSGC 180
  181 NRAMELLTGK SEKQLVGLTP KDVYAPDIAE KVMETDEKVF RHNVSLTYEQ WLVYPDGRKA 240
  241 CFELRKVPFY DRVGKRHGLM GFGRDITERK RYQDALENAS RDKTTFISTI SHELRTPLNG 300
  301 IVGLSRILLD TELDAEQLKY LKTIHVSAIT LGNIFNDIIE MDKLERRKVQ LDNQPVDFTG 360
  361 FMADLENLSG LLVQPKGLKF IMEPQLPLPE KVIADGTRLR QILWNLIGNA VKFTQQGKIV 420
  421 VRVRREGNDR LIFEVEDSGM GIPEDEQDKI FAMYYQVKDR NGGRPATGTG IGLAVSKRLA 480
  481 QSMGGDITVK STQGVGSCFT LTIKAPAVQE ASNAPSGDDM PLPALHVLLV EDIELNVIVA 540
  541 RSVLEKLGNS VDVAMNGHDA LAMFNPEDFD LVLLDIQLPD MSGLDIARQI RAEYGKQSLP 600
  601 PLVALTANVL KDKKEYLDAG MDDVLSKPLS VPALTAMIKQ FWDSKPSSAV QKQEHKVMQT 660
  661 HESLLDTTML EQYIDLVGPQ LIHQSLEMFE QMMPGYLAVL DSNMTARDQK GITEEAHKIK 720
  721 GAAGSVGLRH IQQLAQQIQT PTLPAWWDNV QDWVDELKLE WRNDVQVLRE WAAEVEKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..123] deduced N/A No confident structure predictions are available.
    2 View Details [124..255] PSI-BLAST 6.69897 Crystal Structure of the heme PAS sensor domain of Ec DOS (ferric form)
    3 View Details [256..514] PSI-BLAST 39.39794 Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
    4 View Details [515..778] PSI-BLAST 25.0 Response regulator PleD in complex with c-diGMP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • ion transmembrane transporter activity
    		•  1.94020112661684 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.88422125389203 bayes_pls_golite062009
  • binding
    		•  1.79230776794479 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.70629448457771 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.55042643398568 bayes_pls_golite062009
  • DNA binding
    		•  1.54206275665781 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.45691562840107 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.41817054839611 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.31850321187865 bayes_pls_golite062009
  • transcription factor activity
    		•  1.12946889905444 bayes_pls_golite062009
  • protein binding
    		•  1.0133195984081 bayes_pls_golite062009
  • potassium channel activity
    		•  0.93265112299626 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.92661046549451 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.926512767264521 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  0.92204538811959 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.91469735366704 bayes_pls_golite062009
  • ion channel activity
    		•  0.75430461252947 bayes_pls_golite062009
  • cation channel activity
    		•  0.73262554730695 bayes_pls_golite062009
  • gated channel activity
    		•  0.67217953143815 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.650205954115699 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.64202076714636 bayes_pls_golite062009
  • channel activity
    		•  0.64202076714636 bayes_pls_golite062009
  • two-component sensor activity
    		•  0.58151911764083 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  0.56538125817883 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  0.518111391350209 bayes_pls_golite062009
  • signal transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • transporter activity
    		•  0.360938622392148 bayes_pls_golite062009
  • catalytic activity
    		•  0.285447488878019 bayes_pls_golite062009
  • transcription factor binding
    		•  0.24293756478811 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.217804199010847 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • two-component response regulator activity
    		•  7.02872640261738 bayes_pls_golite062009
  • signal transducer activity
    		•  4.51666042720644 bayes_pls_golite062009
  • molecular transducer activity
    		•  4.51666042720644 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.19396540145756 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  2.35011582062573 bayes_pls_golite062009
  • two-component sensor activity
    		•  2.32303301074957 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  2.28838869071567 bayes_pls_golite062009
  • DNA binding
    		•  1.9200042031022 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.7951051076633 bayes_pls_golite062009
  • transcription factor activity
    		•  1.39074763877806 bayes_pls_golite062009
  • binding
    		•  1.22427537074115 bayes_pls_golite062009
  • protein kinase activity
    		•  1.00737355751913 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.811771244977462 bayes_pls_golite062009
  • kinase activity
    		•  0.725824770559857 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.476057209677045 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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