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Protein Overview: gi|30257806, gi|...

General Information:
Name(s) found: gi|30263172 [NCBI NR]
gi|30257806 [NCBI NR]
Description(s) found:
Found 4 descriptions.
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  • gi|30263172|ref|NP_845549.1| 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Bacillus anthracis str. Ames] [NCBI NR]
  • gi|30257806|gb|AAP27035.1| 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Bacillus anthracis str. Ames] [NCBI NR]
    • Organism: Bacillus anthracis str. Ames
    Length: 328 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: steroid biosynthetic process [ISSLink to PubMed article]
    Molecular Function: 3(or 17)beta-hydroxysteroid dehydrogenase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKMLVTGGTG FLGQKLAFRL KNMGYEVTAT GRNKTIGKVL EQNGIKFVHC PLEDRERVLQ  60
   61 VCKDKDYIFH SGAHSSPWGK YEDFYNANVL GTKHIIEGSQ KYGIKRLIHV STPSIYFYYD 120
  121 ERQNVVENAK LPDTFVNHYA TTKYMAEQAI DQAFAHGLPV ITIRPRALFG PGDNAILPRL 180
  181 IKVCEKGALP RIGTENVLVD ITYVENVVDA LLLCMHSPKH TLGQKYNITN DERINLYEVI 240
  241 ENVMKRLDKE VRYKKISYKT AFTLAAILEG ISKTILFGKE PILTKYTVSV LSKSQTLSID 300
  301 KAKEELGYAP KVSIEEGITK FVDWWKTQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..328] PSI-BLAST 61.69897 Crystal Structure of DesIV (dTDP-glucose 4,6-dehydratase) from Streptomyces venezuelae with NAD and TYD bound

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • steroid dehydrogenase activity
    		•  3.70115036051018 bayes_pls_golite062009
  • steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  3.56748749904419 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  3.08644105481774 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.27417613545298 bayes_pls_golite062009
  • UDP-glucose 4-epimerase activity
    		•  2.13934644118967 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.97774592602866 bayes_pls_golite062009
  • 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
    		•  1.80383455383329 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • receptor activity
    		•  1.59521607141455 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.57495858691649 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.28375985874563 bayes_pls_golite062009
  • signal transducer activity
    		•  1.28375985874563 bayes_pls_golite062009
  • C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
    		•  1.03845584151228 bayes_pls_golite062009
  • retinoid binding
    		•  0.67821643688355 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  0.65743456407889 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  0.648902636946461 bayes_pls_golite062009
  • 11-beta-hydroxysteroid dehydrogenase activity
    		•  0.617411823427239 bayes_pls_golite062009
  • isoprenoid binding
    		•  0.56322670082984 bayes_pls_golite062009
  • binding
    		•  0.553666136934364 bayes_pls_golite062009
  • testosterone 17-beta-dehydrogenase activity
    		•  0.532187027260366 bayes_pls_golite062009
  • ethanol binding
    		•  0.43110794057174 bayes_pls_golite062009
  • retinol binding
    		•  0.40116957175133 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.34220594024072 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.285880800622433 bayes_pls_golite062009
  • DNA binding
    		•  0.199566885140605 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0150328330534928 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle