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View Structure Prediction Details

Protein: gi|30257806, gi|...
Organism: Bacillus anthracis str. Ames
Length: 328 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30257806, gi|....

Description E-value Query
Range
Subject
Range
gi|41205692 - gi|41205692|gb|AAR99612.1| dTDP-glucose 4,6-dehydratase [Geobacillus stearothermophilus]
2.0E-69 [1..327] [3..313]
gi|49329645, gi|... - gi|49478089|ref|YP_037324.1| 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Bacillus ...
4.0E-66 [1..326] [1..326]
gi|51975772, gi|... - gi|52142303|ref|YP_084525.1| 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Bacillus ...
5.0E-66 [1..326] [1..326]
gi|7437238 - pir||H69105 dTDP-glucose 4,6-dehydratase - Methanobacterium thermoautotrophicum (strain Delta H)
gi|15679777, gi|... - gi|2622920|gb|AAB86255.1| dTDP-glucose 4,6-dehydratase [Methanothermobacter thermautotrophicus str. ...
8.0E-66 [2..325] [3..307]
gi|33413324, gi|... - gi|33413324|emb|CAD67949.1| putative dTDP-glucose 4,6-dehydratase [Thermotoga sp. RQ2], gi|170288108...
2.0E-65 [1..327] [1..315]
gi|110599663, gi... - gi|222056234|ref|YP_002538596.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Geobacter sp. FRC-32...
2.0E-64 [1..328] [1..329]
gi|16357461 - gi|16357461|gb|AAL18013.1| dTDP-glucose 4,6-dehydratase [Aneurinibacillus thermoaerophilus]
8.0E-64 [1..326] [1..310]
gi|99077994, gi|... - gi|99077994|ref|YP_611253.1| dTDP-glucose 4,6-dehydratase [Silicibacter sp. TM1040], gi|99034937|gb|...
1.0E-63 [1..326] [1..327]
gi|49529344, gi|... - gi|50083368|ref|YP_044878.1| dTDP-D-glucose-4,6-dehydratase [Acinetobacter sp. ADP1], gi|49529344|em...
2.0E-63 [1..327] [2..333]

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Predicted Domain #1
Region A:
Residues: [1-328]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKMLVTGGTG FLGQKLAFRL KNMGYEVTAT GRNKTIGKVL EQNGIKFVHC PLEDRERVLQ  60
   61 VCKDKDYIFH SGAHSSPWGK YEDFYNANVL GTKHIIEGSQ KYGIKRLIHV STPSIYFYYD 120
  121 ERQNVVENAK LPDTFVNHYA TTKYMAEQAI DQAFAHGLPV ITIRPRALFG PGDNAILPRL 180
  181 IKVCEKGALP RIGTENVLVD ITYVENVVDA LLLCMHSPKH TLGQKYNITN DERINLYEVI 240
  241 ENVMKRLDKE VRYKKISYKT AFTLAAILEG ISKTILFGKE PILTKYTVSV LSKSQTLSID 300
  301 KAKEELGYAP KVSIEEGITK FVDWWKTQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.69897
Match: 1r66A
Description: Crystal Structure of DesIV (dTDP-glucose 4,6-dehydratase) from Streptomyces venezuelae with NAD and TYD bound
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
steroid dehydrogenase activity 3.70115036051018 bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3.56748749904419 bayes_pls_golite062009
retinol dehydrogenase activity 3.08644105481774 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 2.27417613545298 bayes_pls_golite062009
UDP-glucose 4-epimerase activity 2.13934644118967 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.97774592602866 bayes_pls_golite062009
3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity 1.80383455383329 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
receptor activity 1.59521607141455 bayes_pls_golite062009
transmembrane receptor activity 1.57495858691649 bayes_pls_golite062009
molecular transducer activity 1.28375985874563 bayes_pls_golite062009
signal transducer activity 1.28375985874563 bayes_pls_golite062009
C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity 1.03845584151228 bayes_pls_golite062009
retinoid binding 0.67821643688355 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 0.65743456407889 bayes_pls_golite062009
G-protein coupled receptor activity 0.648902636946461 bayes_pls_golite062009
11-beta-hydroxysteroid dehydrogenase activity 0.617411823427239 bayes_pls_golite062009
isoprenoid binding 0.56322670082984 bayes_pls_golite062009
binding 0.553666136934364 bayes_pls_golite062009
testosterone 17-beta-dehydrogenase activity 0.532187027260366 bayes_pls_golite062009
ethanol binding 0.43110794057174 bayes_pls_golite062009
retinol binding 0.40116957175133 bayes_pls_golite062009
oxidoreductase activity 0.34220594024072 bayes_pls_golite062009
nucleic acid binding 0.285880800622433 bayes_pls_golite062009
DNA binding 0.199566885140605 bayes_pls_golite062009
transcription regulator activity 0.0150328330534928 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle