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Protein Overview: gi|24346071, gi|...

General Information:
Name(s) found: gi|24372170 [NCBI NR]
gi|24346071 [NCBI NR]
Description(s) found:
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  • gi|24372170|ref|NP_716212.1| sensory box histidine kinase/response regulator [Shewanella oneidensis MR-1] [NCBI NR]
  • gi|24346071|gb|AAN53657.1|AE015504_7 sensory box histidine kinase/response regulator [Shewanella oneidensis MR-1] [NCBI NR]
  • sensory box histidine kinase/response regulator [Shewanella oneidensis MR-1]gi|24346071|gb|AAN53657.1| sensory box histidine kinase/response regulator [Shewanella oneidensis MR-1] [nrdb_11152004_Chlamydomonas]
  • sensory box histidine kinase/response regulator [Shewanella oneidensis MR-1] [nr-271106-contam.fasta]
    • Organism: Shewanella oneidensis MR-1
    Length: 1188 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: two-component signal transduction system (phosphorelay) [ISSLink to PubMed article]
    Molecular Function: two-component sensor activity [ISSLink to PubMed article]
    two-component response regulator activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQREEQVER HVLQIDLLLE SSIRAVKSLR DVAVDHLRLG ELVRKERLPQ YGKFNESGQY  60
   61 FTLEPNYAKG GKPFTNMGRI TGAGSLDGRS DKFYQELEML FELSLSFPVA KEAAPKASAI 120
  121 YYLSRQRMMS YFPWTNDDER FRDELLNKKQ FQYATPAMNP QRSVFWSEAY VDSTGKGLLT 180
  181 TLGVPVYLDD EFMGSINLDM TLASLARQIR VYFKMPGTVI LLDQQNNILS HSDFDGSDIN 240
  241 RVYHISQRIP SELHSLPESE LFDAHEGIIR NGYYIHSVAL HNAPWRLLYL QNEDDLFQDS 300
  301 VEKLQLTFIL VVIALSVLVT IVHWQTRRSF VSPASRLLSH LEGCSQEPRK PPEKITPGWE 360
  361 PWFLLVSRIF EENKQYTHHL AEQNKRLDKL VARRTERLKD ATERREREYA LLRSLLDSIP 420
  421 EAIVFKDKEG NYLGCNKAAE RMLGYTESEM IGLSSEDLTS PEMGIRIRAE DAQILKDRTP 480
  481 LRYQEKVELA GKPVLLDTLK LPFYNRRGEL QGLIAVWRDV TREYESAEQL RLSEERYHLA 540
  541 MDAVEDGLWD WYLDSEHIIC NPSYYSMLGY KPNEFPALVS AIDQLTHPDD RIRVEEYRNQ 600
  601 YLENPVDAYE IEFRILGKNS SYHWVLSRGR VVEFTTDGQP KRMVGTHKDI TRHKSNEVAL 660
  661 LEAKQDAELA NLYKSEFLAN MSHEIRTPMN AIIGMLQLAQ RTSLTAQQKD YLEKAGFSAQ 720
  721 SLLRIINDIL DFSKIEAGKL ELERVPFPLD KVLDHALDLN ALKAQEQGVE LLLYAPVTAG 780
  781 LILKGDPLRL GQVLINLLSN AVKFTQSGEI ELGCEDVGER DHRITLKFWV RDTGIGISKD 840
  841 QQEKLFDAFA QADGSTTRKY GGTGLGLSIS KHLVSMMGGK MQVQSELGVG STFSFTISFE 900
  901 IAEEAKIEPL VVPEKLNNLR TLVVDDNPTA LQIYSALMRD FHFEVDTAAS GAEALYKLSR 960
  961 DPIDLLLLDW MMPEMDGSDV ISAIDTMVAE GRIAKRPIII MMTAYAAEPL LHEVDSANVF1020
 1021 AVLQKPFKAS SLFDEIIAAF ADEPRLNVVQ PIAEVAVEEG EHTGLVLLVE DNFINQQVAT1080
 1081 ELLKSAGYEV VVAGNGQIAL DIVDSRPFDA VLMDIQMPVM DGLTAARALR ERYSADVLPI1140
 1141 IAMTAHAMSG DREKSLAAGM NAHITKPIVL TELFETLTHW IKHKHNHR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..347] FFAS03 3.96 No description for 2p7jA was found.
    2 View Details [348..513] FFAS03 4.54 Crystal Structure of the heme PAS sensor domain of Ec DOS (ferric form)
    3 View Details [514..649] PSI-BLAST 6.09691 Histidine kinase FixL heme domain
    4 View Details [650..902] PSI-BLAST 42.0 Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
    5 View Details [903..1188] PSI-BLAST 36.30103 Response regulator PleD in complex with c-diGMP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • two-component sensor activity
    		•  2.88093868237858 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  2.86151216540335 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  2.80671328721504 bayes_pls_golite062009
  • protein kinase activity
    		•  1.74105675066805 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.62873572477094 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.58981311381645 bayes_pls_golite062009
  • kinase activity
    		•  1.5133458700147 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.31628115739307 bayes_pls_golite062009
  • signal transducer activity
    		•  1.10204821596482 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.10204821596482 bayes_pls_golite062009
  • catalytic activity
    		•  0.970922685016416 bayes_pls_golite062009
  • transferase activity
    		•  0.839270468560673 bayes_pls_golite062009
  • binding
    		•  0.704248066961418 bayes_pls_golite062009
    2
    Term Confidence Notes
  • ion transmembrane transporter activity
    		•  1.81312487233411 bayes_pls_golite062009
  • binding
    		•  1.67984576110273 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.60314341650446 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.41577088905201 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.40823491489039 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.10325694432704 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.931375605669218 bayes_pls_golite062009
  • protein binding
    		•  0.888256242702267 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.563198063703829 bayes_pls_golite062009
  • potassium channel activity
    		•  0.563028071397075 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.552480950289765 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.551619757281389 bayes_pls_golite062009
  • DNA binding
    		•  0.533187513797767 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  0.532581714382914 bayes_pls_golite062009
  • ion channel activity
    		•  0.483348490364346 bayes_pls_golite062009
  • two-component sensor activity
    		•  0.466388018187262 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  0.452475261443277 bayes_pls_golite062009
  • cation channel activity
    		•  0.445728116294453 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  0.409938237891918 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.391671932145714 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.388177774524707 bayes_pls_golite062009
  • channel activity
    		•  0.388177774524707 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.387046112137798 bayes_pls_golite062009
  • gated channel activity
    		•  0.383085563903689 bayes_pls_golite062009
  • signal transducer activity
    		•  0.341738261779128 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.341738261779128 bayes_pls_golite062009
  • catalytic activity
    		•  0.335650048048265 bayes_pls_golite062009
  • transporter activity
    		•  0.308330515689802 bayes_pls_golite062009
  • transcription factor activity
    		•  0.15709070306709 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.154730712374367 bayes_pls_golite062009
    3
    Term Confidence Notes
  • ion transmembrane transporter activity
    		•  1.94020112661684 bayes_pls_golite062009
  • binding
    		•  1.79230776794479 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.70629448457771 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.55042643398568 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.45691562840107 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.31850321187865 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.13913685347546 bayes_pls_golite062009
  • protein binding
    		•  1.0133195984081 bayes_pls_golite062009
  • potassium channel activity
    		•  0.93265112299626 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.92661046549451 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.926512767264521 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  0.92204538811959 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.91469735366704 bayes_pls_golite062009
  • ion channel activity
    		•  0.75430461252947 bayes_pls_golite062009
  • cation channel activity
    		•  0.73262554730695 bayes_pls_golite062009
  • DNA binding
    		•  0.73243452463464 bayes_pls_golite062009
  • gated channel activity
    		•  0.67217953143815 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.650205954115699 bayes_pls_golite062009
  • channel activity
    		•  0.64202076714636 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.64202076714636 bayes_pls_golite062009
  • two-component sensor activity
    		•  0.58151911764083 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  0.56538125817883 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.5545839402512 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  0.518111391350209 bayes_pls_golite062009
  • signal transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • transcription factor activity
    		•  0.36759096137141 bayes_pls_golite062009
  • transporter activity
    		•  0.360938622392148 bayes_pls_golite062009
  • catalytic activity
    		•  0.285447488878019 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.217804199010847 bayes_pls_golite062009
    4 No functions predicted.
    5
    Term Confidence Notes
  • two-component response regulator activity
    		•  7.02872640261738 bayes_pls_golite062009
  • signal transducer activity
    		•  4.51666042720644 bayes_pls_golite062009
  • molecular transducer activity
    		•  4.51666042720644 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.44888100104099 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  2.35011582062573 bayes_pls_golite062009
  • two-component sensor activity
    		•  2.32303301074957 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  2.28838869071567 bayes_pls_golite062009
  • binding
    		•  1.22427537074115 bayes_pls_golite062009
  • DNA binding
    		•  1.11037597107903 bayes_pls_golite062009
  • protein kinase activity
    		•  1.00737355751913 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.93151849951839 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.811771244977462 bayes_pls_golite062009
  • kinase activity
    		•  0.725824770559857 bayes_pls_golite062009
  • transcription factor activity
    		•  0.62886970109503 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.476057209677045 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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