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Protein Overview: SXM1_YEAST

General Information:
Name(s) found: SXM1_YEAST [Swiss-Prot]
Description(s) found:
Found 2 descriptions.
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  • Importin beta SMX1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SXM1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 944 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQEQAILSC IEQTMVADAK IIKEAEQQLF EFQKQPGFTS FLLNIVSDDN FALNVRLSSA  60
   61 IYLKNKIHRS WDTKREDGIK ADEKLSIKER LIETLVKNCE NNHIRPILTE TINGILVGQE 120
  121 DWDLAPIIKN LLSSGDASYI YPGLLLLFQL CKAHRWDMVG SRDYIDSVIE ELFPIVEGIA 180
  181 SNIGSQTDYR SNEILYLILK SFKYACLNNL PQYFSQPERI MSWVQLHLYL CSKPLPVEVM 240
  241 ELDPADRSLD KRVKVNKWGF GNLNRFLQRY NKITKAITKE FIDYIFNTIV PIILREFFKD 300
  301 IEAWGNNSLW LSDSSLYFLI SFLEKCVTID QLYPLIEPHL QIIFENVIFP CLCANEQSIE 360
  361 LLEDDQEEYT RRYFDINREG STPDAASADF IFLIGSKRPE KLNNILPFIN DIFTRFDANS 420
  421 SDINMAFKEE GALRTLSNLF SFIDEPSVLE NIFGHFIVPL LSQDKYMFLV ARSLETIALY 480
  481 SEEFKDMNIL SQLFELTYTN FLNSNVLPVQ IEAADAIKCL IVSNPQIHPA VSAHVPGMME 540
  541 KLLKLSKIFE IDILSEVMEA LVERFSDELS PFAKDLASNL VEQFLRIAQA LVENPSETYS 600
  601 ASDQEQEIQA SGLLQTMTTM VMSMNKVPLI ESLAPVVKFV VLHAQISFIT EAVDLLDALT 660
  661 ISSHLLYNQI APPIWELLHD ILDSFQTYAM DYFEAYSIFF ETIVMTGFPQ DQTYVQPLLE 720
  721 ILSAKLESEV DYDIEHVMQI LMYFALSMRD IPLFSKAIKV STNDELGLDS KCIVKLGLAN 780
  781 LFAKPIETLQ IMENEGFTIN FFTNWFNEKF YSVFAIKLQV LVILTLLKMP EVPNSVSPLL 840
  841 NNLTNKLVEL TLSLPKAIRN RDAVTEGKSL EGDLTPEEEE EYFIECDDDM KETVLDQINV 900
  901 FQEVHTFFKN LQNEDAGKYE KIINYLDESK RDSLQVILEF VSQH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..254] PSI-BLAST 83.69897 Importin beta
    2 View Details [255..484] PSI-BLAST 83.69897 Importin beta
    3 View Details [485..605] PSI-BLAST 83.69897 Importin beta
    4 View Details [606..795] PSI-BLAST 83.69897 Importin beta
    5 View Details [796..944] MSA 1.053979 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein transporter activity
    		•  4.58709163830613 bayes_pls_golite062009
  • binding
    		•  3.0667965351474 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  2.74547353635661 bayes_pls_golite062009
  • transporter activity
    		•  2.48700774379895 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.26725422172281 bayes_pls_golite062009
  • nuclear export signal receptor activity
    		•  2.13470398426489 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.97003189625955 bayes_pls_golite062009
  • nuclear localization sequence binding
    		•  1.91487015967262 bayes_pls_golite062009
  • protein binding
    		•  1.73688475473996 bayes_pls_golite062009
  • signal transducer activity
    		•  1.51103985174196 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.51103985174196 bayes_pls_golite062009
  • actin binding
    		•  1.4328432044371 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.28481004323799 bayes_pls_golite062009
  • RNA binding
    		•  1.20550543134698 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.09652988954158 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.00841167631924 bayes_pls_golite062009
  • peptide binding
    		•  0.61212282188613 bayes_pls_golite062009
  • signal sequence binding
    		•  0.57106697498903 bayes_pls_golite062009
  • structural molecule activity
    		•  0.449804281824548 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.385452858197632 bayes_pls_golite062009
  • mRNA binding
    		•  0.37278269424461 bayes_pls_golite062009
  • DNA binding
    		•  0.309260217284589 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.252495966234234 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.248585912061178 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.226380819487924 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.217517113570989 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.178770060806735 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.175241020572885 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.174922130116569 bayes_pls_golite062009
  • receptor binding
    		•  0.100410929582364 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.100181463251306 bayes_pls_golite062009
  • protein phosphatase binding
    		•  0.0960864951500202 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0635404099346928 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0548082069333885 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.052195223119721 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0405268469927988 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle