Protein Overview: M3K11_RAT

General Information:
Name(s) found:	M3K11_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|81910672\|sp\|Q66HA1.1\|M3K11_RAT RecName: Full=Mitogen-activated protein kinase kinase kinase 11; AltName: Full=Mixed lineage kinase 3 [NCBI NR] gi\|61557106\|ref\|NP_001013168.1\| mitogen-activated protein kinase kinase kinase 11 [Rattus norvegicus] [NCBI NR] gi\|51858693\|gb\|AAH81952.1\| Mitogen-activated protein kinase kinase kinase 11 [Rattus norvegicus] [NCBI NR] Mitogen-activated protein kinase kinase kinase 11 OS=Rattus norvegicus GN=Map3k11 PE=1 SV=1 [Swiss-Prot] Unknown (protein for MGC:94039) [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Mitogen-activated protein kinase kinase kinase 11 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Hypothetical protein [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] mitogen-activated protein kinase kinase kinase 11 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Mitogen-activated protein kinase kinase kinase 11 (Mixed lineage kinase 3) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Mitogen-activated protein kinase kinase kinase 11 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 HYPOTHETICAL PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Map3k11 Mitogen-activated protein kinase kinase kinase 11 [rat-ipi-250309-contam.fasta] Mitogen-activated protein kinase kinase kinase 11 OS=Rattus norvegicus GN=Map3k11 [011711_HMR.fasta] Mitogen-activated protein kinase kinase kinase 11 OS=Rattus norvegicus GN=Map3k11 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	850 amino acids
Gene Ontology:
Cellular Component:	centrosome [UNKNOWN][IEA] soluble fraction [IDA] cytoskeleton [IEA] cytoplasm [IEA] microtubule [UNKNOWN][IEA]
Biological Process:	cell proliferation [UNKNOWN][IEA] activation of JNKK activity [IDA] activation of JUN kinase activity [UNKNOWN][IEA] protein amino acid autophosphorylation [UNKNOWN][IDA] JNK cascade [IDA] protein amino acid phosphorylation [UNKNOWN][IDA] positive regulation of neuron apoptosis [IMP] microtubule-based process [UNKNOWN][IEA] regulation of JNK cascade [UNKNOWN][IEA] activation of MAPK activity [UNKNOWN] cell death [IMP] positive regulation of apoptosis [IMP] G1 phase of mitotic cell cycle [UNKNOWN][IEA] protein oligomerization [UNKNOWN][IEA]
Molecular Function:	nucleotide binding [IEA] ATP binding [IDA] protein binding [UNKNOWN][IPI] protein homodimerization activity [UNKNOWN][IEA] JUN kinase kinase kinase activity [IDA] Rac GTPase binding [IPI] MAP kinase kinase kinase activity [IDA] protein serine/threonine kinase activity [UNKNOWN][IDA] transferase activity [IEA] mitogen-activated protein kinase kinase binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPLKNLFLK SPLGSWNGSG SGGGGGSGGV RPEGSPKATA AYANPVWTAL FDYEPNGQDE  60
   61 LALRKGDRVE VLSRDAAISG DEGWWAGQVG GQVGIFPSNY VSRGGGPPPC EVASFQELRL 120
  121 EEVIGIGGFG KVYRGSWRGE LVAVKAARQD PDEDISVTAE SVRQEARLFA MLAHPNIIAL 180
  181 KAVCLEEPNL CLVMEYAAGG PLSRALAGRR VPPHVLVNWA VQIARGMHYL HCEALVPVIH 240
  241 RDLKSNNILL LQPIEGDDME HKTLKITDFG LAREWHKTTQ MSAAGTYAWM APEVIKASTF 300
  301 SKGSDVWSFG VLLWELLTGE VPYRGIDCLA VAYGVAVNKL TLPIPSTCPE PFAQLMADCW 360
  361 AQDPHRRPDF ASILQQLEAL EAQVLREMPR DSFHSMQEGW KREIQGLFDE LRAKEKELLS 420
  421 REEELTRAAR EQRSQAEQLR RREHLLAQWE LEVFERELTL LLQQVDRERP HVRRRRGTFK 480
  481 RSKLRARDGG ERISMPLDFK HRITVQASPG LDRRRNVFEV GAGDSPTFPR FRAIQLEPAE 540
  541 SGQTWGRQSP RRLDDSSNGE RRACWAWGPS SPKPGEAQNG RRRSRMDEAT WYLDSDDSSP 600
  601 LGSPSTPPAL NGNPPRPSPE PEEPRRSGPT ERGNSSGTPK LIQRALLRGT ALLASLGLGR 660
  661 DLQPPGGLSR ERGESPTAPP PAQMASPCPP DLPSTPLIHL SQATPDARGP LTPAPLLLDL 720
  721 GVSSGQPSAK SPRREETRGR TVSPPPGISR SAPGTPGTPR SPPLGLISRP RPSPLRNRID 780
  781 PWSFVSAGPR PSPLPSPQPA PRRAPWTLFP DSDPFWDSPP ANPFRGGSQD CRTQTKDVGA 840
  841 QAPWAPEAGP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Protein Overview: M3K11_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: