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Protein Overview: ADH1_ARATH

General Information:
Name(s) found: ADH1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|469467|emb|CAA54911.1| alcohol dehydrogenase [Arabidopsis thaliana] [NCBI NR]
  • gi|46137879|gb|AAS45601.2| alcohol dehydrogenase [Arabidopsis thaliana] [NCBI NR]
  • gi|2829917|gb|AAC00625.1| Alcohol Dehydrogenase [Arabidopsis thaliana] [NCBI NR]
  • gi|2570194|dbj|BAA22981.1| alcohol dehydrogenase [Arabidopsis thaliana] [NCBI NR]
  • gi|19699250|gb|AAL90991.1| AT1g77120/T14N5.18 [Arabidopsis thaliana] [NCBI NR]
  • gi|1944214|dbj|BAA19619.1| alcohol dehydrogenase [Arabidopsis thaliana] [NCBI NR]
  • gi|15223838|ref|NP_177837.1| ADH1 (ALCOHOL DEHYDROGENASE 1); alcohol dehydrogenase [Arabidopsis thaliana] [NCBI NR]
  • gi|15010622|gb|AAK73970.1| AT1g77120/T14N5.18 [Arabidopsis thaliana] [NCBI NR]
  • gi|148841208|sp|P06525.2|ADH1_ARATH RecName: Full=Alcohol dehydrogenase class-P [NCBI NR]
  • Alcohol dehydrogenase class-P OS=Arabidopsis thaliana GN=ADH1 PE=1 SV=2 [Swiss-Prot]
  • Alcohol Dehydrogenase [Arabidopsis thaliana]gi|469467|emb|CAA54911.1| alcohol dehydrogenase [Arabidopsis thaliana]gi|19699250|gb|AAL90991.1| AT1g77120/T14N5.18 [Arabidopsis thaliana]gi|15010622|gb|AAK73970.1| AT1g77120/T14N5.18 [Arabidopsis thaliana]g [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 The protein undergoes thiolation following treatment with the oxidant tert-butylhydroperoxide [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ADH, ATADH, ADH1 | ADH1 (ALCOHOL DEHYDROGENASE 1) | chr1:28980403-28982110 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • alcohol dehydrogenase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • AT1g77120/T14N5.18 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Alcohol Dehydrogenase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ADH1 (ALCOHOL DEHYDROGENASE 1); alcohol dehydrogenase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ADH1, ADH, ATADH, ATADH1 | alcohol dehydrogenase 1 | chr1:28975509-28977216 FORWARD LENGTH=379 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 379 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDA]
    plasma membrane [IDA]
    Biological Process: response to hypoxia [IEP]
    response to salt stress [IEP]
    response to osmotic stress [IGI]
    cellular respiration [TAS]
    response to cadmium ion [IEP]
    Molecular Function: alcohol dehydrogenase (NAD) activity [IMP][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTTGQIIRC KAAVAWEAGK PLVIEEVEVA PPQKHEVRIK ILFTSLCHTD VYFWEAKGQT  60
   61 PLFPRIFGHE AGGIVESVGE GVTDLQPGDH VLPIFTGECG ECRHCHSEES NMCDLLRINT 120
  121 ERGGMIHDGE SRFSINGKPI YHFLGTSTFS EYTVVHSGQV AKINPDAPLD KVCIVSCGLS 180
  181 TGLGATLNVA KPKKGQSVAI FGLGAVGLGA AEGARIAGAS RIIGVDFNSK RFDQAKEFGV 240
  241 TECVNPKDHD KPIQQVIAEM TDGGVDRSVE CTGSVQAMIQ AFECVHDGWG VAVLVGVPSK 300
  301 DDAFKTHPMN FLNERTLKGT FFGNYKPKTD IPGVVEKYMN KELELEKFIT HTVPFSEINK 360
  361 AFDYMLKGES IRCIITMGA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..379] PSI-BLAST 109.0 Alcohol dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ethanol binding
    		•  4.47659026306883 bayes_pls_golite062009
  • NAD or NADH binding
    		•  4.35058438816264 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  4.1750549780559 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.09625241707629 bayes_pls_golite062009
  • methylglyoxal reductase (NADH-dependent) activity
    		•  3.00190838171391 bayes_pls_golite062009
  • alcohol binding
    		•  2.97042200128883 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  2.94416173750168 bayes_pls_golite062009
  • retinol binding
    		•  2.89007863838685 bayes_pls_golite062009
  • all-trans retinal binding
    		•  2.84803957533249 bayes_pls_golite062009
  • S-(hydroxymethyl)glutathione dehydrogenase activity
    		•  2.58673703881996 bayes_pls_golite062009
  • hydroxymethylfurfural reductase activity
    		•  2.2999175117758 bayes_pls_golite062009
  • hydroxymethylfurfural reductase (NADH) activity
    		•  2.2999175117758 bayes_pls_golite062009
  • alcohol dehydrogenase activity, zinc-dependent
    		•  2.26153457113968 bayes_pls_golite062009
  • NADPH:quinone reductase activity
    		•  2.16668841986245 bayes_pls_golite062009
  • benzaldehyde dehydrogenase activity
    		•  2.03039843216597 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  1.87993822355695 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.65338499044318 bayes_pls_golite062009
  • DNA binding
    		•  1.61355789916908 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.55390653047158 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.48478425318425 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.47309297191111 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  1.22444609393125 bayes_pls_golite062009
  • chaperone binding
    		•  1.19079350615542 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  1.01627645289834 bayes_pls_golite062009
  • binding
    		•  0.982999356179965 bayes_pls_golite062009
  • transcription factor activity
    		•  0.91090893050278 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.788034697021177 bayes_pls_golite062009
  • structural molecule activity
    		•  0.75267483298133 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  0.62461633437589 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  0.621273823467575 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.523513694229008 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.484089941059577 bayes_pls_golite062009
  • kinase activity
    		•  0.461063813999598 bayes_pls_golite062009
  • hydroxymethylfurfural reductase (NADPH) activity
    		•  0.382131941157781 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.375415252607746 bayes_pls_golite062009
  • coenzyme binding
    		•  0.35922330382799 bayes_pls_golite062009
  • protein kinase activity
    		•  0.339420053437627 bayes_pls_golite062009
  • 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
    		•  0.320177384202291 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  0.233238483713519 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  0.216422278300306 bayes_pls_golite062009
  • methylenetetrahydrofolate dehydrogenase activity
    		•  0.169301675015808 bayes_pls_golite062009
  • methenyltetrahydrofolate cyclohydrolase activity
    		•  0.162625185692811 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  0.0962368786590111 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle