YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: Ada2b-PB

General Information:
Name(s) found: Ada2b-PB / FBpp0099776 [FlyBase]
Description(s) found:
Found 19 descriptions.
SHOW ALL
  • The gene Ada2b is referred to in FlyBase by the symbol Dmel\Ada2b (CG9638, FBgn0037555). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4062838..4066234. It has the cytological map location 84F5. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of histone acetylation; histone H3 acetylation; cell proliferation; regulation of transcription; eye pigment metabolic process; axon target recognition; chromatin remodeling. 14 alleles are reported. The phenotypes of these alleles are annotated with: glial cell; eye. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 555 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    polytene chromosome [IDA]
    SAGA complex [IPI][NAS]
    Biological Process: positive regulation of histone acetylation [IMP]
    cell proliferation [IDA]
    histone H3 acetylation [IDA]
    chromatin remodeling [IDA]
    eye pigment metabolic process [IDA]
    regulation of transcription [IDA][IEA]
    axon target recognition [IMP]
    Molecular Function: histone acetyltransferase activity [NAS]
    DNA binding [IEA]
    zinc ion binding [IEA]
    protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTIADLFTK YNCTNCQDDI QGIRVHCAEC ENFDLCLQCF AAGAEIGAHQ NNHSYQFMDT  60
   61 GTSILSVFRG KGAWTAREEI RLLDAIEQYG FGNWEDISKH IETKSAEDAK EEYVNKFVNG 120
  121 TIGRATWTPA QSQRPRLIDH TGDDDAGPLG TNALSTLPPL EINSDEAMQL GYMPNRDSFE 180
  181 REYDPTAEQL ISNISLSSED TEVDVMLKLA HVDIYTRRLR ERARRKRMVR DYQLVSNFFR 240
  241 NRNYAQQQGL TKEQREFRDR FRVYAQFYTC NEYERLLGSL EREKELRIRQ SELYRYRYNG 300
  301 LTKIAECTHF EQHAATATHR STGPYGHGKT DHTHTSNGSH RPPSSSLHSP QPNLRKVEMS 360
  361 SGGEASSNSI APRNTLHIAD PTCSGALLPS KNYLDSCRGS SAATMLQTTG MVMGVTVDSG 420
  421 ATTGVTSTAT TMANLPTNSA KGSQQHLQPL QQHPQLLQSG NQHKMQNEAA GGGSDQVPSM 480
  481 SLKLRTQLEE LKHLPQPPGS ELLSHNELDL CKKHNITPTT YLSVKTVCLS GAPSLGSPME 540
  541 TSLRKFFIKC GWLSH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..63] FFAS03 2.87 No description for 2e5rA was found.
    2 View Details [64..178] PSI-BLAST 23.221849 c-Myb, DNA-binding domain
    3 View Details [179..354] MSA 4.470995 View MSA. No confident structure predictions are available.
    4 View Details [355..477] deduced N/A No confident structure predictions are available.
    5 View Details [478..555] PSI-BLAST 15.0 Structural and functional analysis of ada2 alpha swirm domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • histone acetyltransferase activity
    		•  5.80609397811031 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  5.80609397811031 bayes_pls_golite062009
  • transcription regulator activity
    		•  5.13863038737912 bayes_pls_golite062009
  • DNA binding
    		•  4.66369707598026 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  4.57418118498868 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  4.37954729923498 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.20953772435302 bayes_pls_golite062009
  • transcription factor activity
    		•  4.06706589695599 bayes_pls_golite062009
  • acetyltransferase activity
    		•  3.80908511328212 bayes_pls_golite062009
  • acyltransferase activity
    		•  3.35206890637362 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.30532537006075 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  3.08442186629685 bayes_pls_golite062009
  • binding
    		•  3.02779747447702 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.41271657675151 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.26183812259792 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.91962622287073 bayes_pls_golite062009
  • protein binding
    		•  1.88087411289001 bayes_pls_golite062009
  • transcription activator activity
    		•  1.77700860354597 bayes_pls_golite062009
  • transcription factor binding
    		•  1.40653841901929 bayes_pls_golite062009
  • protein deacetylase activity
    		•  1.23680480131205 bayes_pls_golite062009
  • histone deacetylase activity
    		•  1.18932416576802 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.14886080629275 bayes_pls_golite062009
  • chromatin binding
    		•  0.876241359231159 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.84983974758882 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.663171909351326 bayes_pls_golite062009
  • histone binding
    		•  0.557787598121402 bayes_pls_golite062009
  • deacetylase activity
    		•  0.530687254192222 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.2679415219517 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.25931464844298 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.236060274498333 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.141400887946529 bayes_pls_golite062009
  • telomeric DNA binding
    		•  0.0735027998484772 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • histone acetyltransferase activity
    		•  5.80609397811031 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  5.80609397811031 bayes_pls_golite062009
  • transcription regulator activity
    		•  5.13863038737912 bayes_pls_golite062009
  • DNA binding
    		•  4.66369707598026 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  4.57418118498868 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  4.37954729923498 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.20953772435302 bayes_pls_golite062009
  • transcription factor activity
    		•  4.06706589695599 bayes_pls_golite062009
  • acetyltransferase activity
    		•  3.80908511328212 bayes_pls_golite062009
  • acyltransferase activity
    		•  3.35206890637362 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.30532537006075 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  3.08442186629685 bayes_pls_golite062009
  • binding
    		•  3.02779747447702 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.41271657675151 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.26183812259792 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.91962622287073 bayes_pls_golite062009
  • protein binding
    		•  1.88087411289001 bayes_pls_golite062009
  • transcription activator activity
    		•  1.77700860354597 bayes_pls_golite062009
  • transcription factor binding
    		•  1.40653841901929 bayes_pls_golite062009
  • protein deacetylase activity
    		•  1.23680480131205 bayes_pls_golite062009
  • histone deacetylase activity
    		•  1.18932416576802 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.14886080629275 bayes_pls_golite062009
  • chromatin binding
    		•  0.876241359231159 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.84983974758882 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.663171909351326 bayes_pls_golite062009
  • histone binding
    		•  0.557787598121402 bayes_pls_golite062009
  • deacetylase activity
    		•  0.530687254192222 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.2679415219517 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.25931464844298 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.236060274498333 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.141400887946529 bayes_pls_golite062009
  • telomeric DNA binding
    		•  0.0735027998484772 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle