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Protein Overview: CUL4_ARATH

General Information:
Name(s) found: CUL4_ARATH [Swiss-Prot]
Description(s) found:
Found 9 descriptions.
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  • Cullin-4 OS=Arabidopsis thaliana GN=CUL4 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 792 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    ubiquitin ligase complex [IPI]
    CUL4 RING ubiquitin ligase complex [IPI]
    Biological Process: DNA repair [IMP]
    fruit development [IMP]
    photomorphogenesis [IMP]
    protein polyubiquitination [IDA]
    sugar mediated signaling pathway [IMP]
    cell cycle [ISS]
    cotyledon development [IMP]
    hormone-mediated signaling pathway [IMP]
    flower development [IMP]
    shoot development [IMP]
    leaf development [IMP]
    short-day photoperiodism, flowering [IMP]
    negative regulation of photomorphogenesis [IMP]
    Molecular Function: protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLPTKRSTF SAASASDDSS YSSPPMKKAK NDLHHSPQHP NTADKVVGFH MEEDPTPAAA  60
   61 NLSRKKATLP QPTKKFVIKL NKAKPTLPTN FEENTWEKLQ SAIRAIFLKK KISFDLESLY 120
  121 QAVDNLCLHK LDGKLYDQIE KECEEHISAA LQSLVGQNTD LTVFLSRVEK CWQDFCDQML 180
  181 MIRSIALTLD RKYVIQNPNV RSLWEMGLQL FRKHLSLAPE VEQRTVKGLL SMIEKERLAE 240
  241 AVNRTLLSHL LKMFTALGIY MESFEKPFLE GTSEFYAAEG MKYMQQSDVP EYLKHVEGRL 300
  301 HEENERCILY IDAVTRKPLI TTVERQLLER HILVVLEKGF TTLMDGRRTE DLQRMQTLFS 360
  361 RVNALESLRQ ALSSYVRKTG QKIVMDEEKD KDMVQSLLDF KASLDIIWEE SFYKNESFGN 420
  421 TIKDSFEHLI NLRQNRPAEL IAKFLDEKLR AGNKGTSEEE LESVLEKVLV LFRFIQGKDV 480
  481 FEAFYKKDLA KRLLLGKSAS IDAEKSMISK LKTECGSQFT NKLEGMFKDI ELSKEINESF 540
  541 KQSSQARTKL PSGIEMSVHV LTTGYWPTYP PMDVKLPHEL NVYQDIFKEF YLSKYSGRRL 600
  601 MWQNSLGHCV LKADFSKGKK ELAVSLFQAV VLMLFNDAMK LSFEDIKDST SIEDKELRRT 660
  661 LQSLACGKVR VLQKNPKGRD VEDGDEFEFN DEFAAPLYRI KVNAIQMKET VEENTSTTER 720
  721 VFQDRQYQID AAIVRIMKTR KVLSHTLLIT ELFQQLKFPI KPADLKKRIE SLIDREYLER 780
  781 EKSNPQIYNY LA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..792] PSI-BLAST 1000.0 No description for 2hyeC was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  9.95820721075934 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  9.63704265478699 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  8.59660059921406 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  7.32718329074249 bayes_pls_golite062009
  • vasopressin activated calcium mobilizing receptor activity
    		•  6.69190468636718 bayes_pls_golite062009
  • transcription regulator activity
    		•  5.55329976718261 bayes_pls_golite062009
  • transcription factor activity
    		•  4.33152142980289 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.85678231380989 bayes_pls_golite062009
  • ligase activity
    		•  3.6057341267609 bayes_pls_golite062009
  • binding
    		•  2.45185337633142 bayes_pls_golite062009
  • transcription activator activity
    		•  2.37668609508629 bayes_pls_golite062009
  • protein binding
    		•  2.34145982999922 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.21939548334548 bayes_pls_golite062009
  • DNA binding
    		•  2.06132216820898 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.70025468248325 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.33374581364046 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.96257232341735 bayes_pls_golite062009
  • transporter activity
    		•  0.891050405674973 bayes_pls_golite062009
  • transcription factor binding
    		•  0.85714789329232 bayes_pls_golite062009
  • DNA replication origin binding
    		•  0.71823621709622 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.697234220778482 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.648150681919233 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.368917395770011 bayes_pls_golite062009
  • catalytic activity
    		•  0.351553138703956 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.322180400748724 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.300899564141452 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.286130392009263 bayes_pls_golite062009
  • structural molecule activity
    		•  0.272316540117209 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.257777071965243 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.249771970501337 bayes_pls_golite062009
  • hydrolase activity
    		•  0.140191206949582 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.107671044044222 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.0912115683429473 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.0856082199488197 bayes_pls_golite062009
  • transferase activity
    		•  0.064832527337659 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.57

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle