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Protein Overview: COB23_ARATH

General Information:
Name(s) found: COB23_ARATH [Swiss-Prot]
Description(s) found:
Found 11 descriptions.
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  • Coatomer subunit beta'-3 OS=Arabidopsis thaliana GN=At3g15980 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 909 amino acids

    Gene Ontology:
    Cellular Component: membrane coat [IEA]
    COPI vesicle coat [ISS]
    Biological Process: vesicle-mediated transport [IEA]
    intracellular protein transport [IEA]
    Molecular Function: protein binding [IEA]
    structural molecule activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLRLDIKRK FAQRSERVKS VDLHPTEPWI LASLYSGTVC IWNYQTQTIT KSFEVTELPV  60
   61 RSAKFIPRKQ WVVAGADDMY IRVYNYNTMD KVKVFEAHSD YIRCVAVHPT LPYVLSSSDD 120
  121 MLIKLWDWEN GWACTQIFEG HSHYVMQVVF NPKDTNTFAS ASLDRTIKIW NLGSPDPNFT 180
  181 LDAHQKGVNC VDYFTGGDKP YLITGSDDHT AKVWDYQTKS CVQTLDGHTH NVSAVCFHPE 240
  241 LPIIITGSED GTVRIWHATT YRLENTLNYG LERVWAIGYI KSSRRVVIGY DEGTIMVKLG 300
  301 REIPVASMDS SGKIIWAKHN EIQTANIKSI GAGYEATDGE RLPLSVKELG TCDLYPQSLK 360
  361 HNPNGRFVVV CGDGEYIIYT ALAWRNRSFG SGLEFVWSSE GECAVRESSS KIKIFSKNFQ 420
  421 ERKSIRPTFS AEKIFGGTLL AMCSNDFICF YDWAECRLIQ QIDVTVKNLY WAESGDLVAI 480
  481 ASDTSFYILK YNRELVSSHF DSGRPTDEEG VEDAFEVLHE NDERVRTGIW VGDCFIYNNS 540
  541 SWKLNYCVGG EVTTMYHLDR PMYLLGYIAN QSRVYLVDKE FNVIGYTLLL SLIEYKTLVM 600
  601 RGDLDRANQI LPTIPKEQHN NVAHFLESRG MIEDALEIAT DPDYKFDLAI QLGRLEIAKE 660
  661 IAEEVQSESK WKQLGELAMS SGKLQLAEDC MKYAMDLSGL LLLYSSLGDA EGVSKLACLA 720
  721 KEQGKNNVAF LCLFTLGRLE DCLQLLVESN RIPEAALMAR SYLPSKVSEI VALWREDLSK 780
  781 VNPKAAESLA DPEEYSNLFE DWQVALSVEA NTAETRGVYT AAENYPSHAD KPSITLVEAF 840
  841 RNLQVEAEES LENGNIDHEV AEENGHVENE GDEEEQQEEE VNEEEGVVDA DSTDGAVLVN 900
  901 GSEVLTPHP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..226] PSI-BLAST 85.522879 PAF-AH Holoenzyme: Lis1/Alfa2
    2 View Details [227..639] PSI-BLAST 4.69897 Crystal Structure of human dipeptidyl peptidase IV in complex with a decapeptide (tNPY) at 2.3 Ang. Resolution
    3 View Details [640..909] FFAS03 0.97 Plasmodium falciparum putative FK506-binding protein PFL2275c, C-terminal TPR-containing domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • histone methyltransferase activity (H3-K4 specific)
    		•  4.71992275913384 bayes_pls_golite062009
  • GTPase activity
    		•  4.02994814377904 bayes_pls_golite062009
    		• 3.48848918010996 bayes_pls_golite062009
  • actin binding
    		•  3.31804728298431 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.25521258308263 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.1056443224755 bayes_pls_golite062009
  • tubulin binding
    		•  2.76945430061825 bayes_pls_golite062009
  • microtubule binding
    		•  2.72684103222924 bayes_pls_golite062009
  • dynein binding
    		•  2.54821997913979 bayes_pls_golite062009
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.3610959773142 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.30918780727915 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.29049708962212 bayes_pls_golite062009
  • RNA binding
    		•  2.1927334052131 bayes_pls_golite062009
  • dynactin binding
    		•  1.92897254169098 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  1.85632145559025 bayes_pls_golite062009
  • DNA binding
    		•  1.71685536470455 bayes_pls_golite062009
  • actin filament binding
    		•  1.5197243426595 bayes_pls_golite062009
  • structural molecule activity
    		•  1.47448876401574 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.41752877005447 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  1.35170368882651 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.22384651674093 bayes_pls_golite062009
  • protein binding
    		•  1.21879977456466 bayes_pls_golite062009
  • transporter activity
    		•  1.21549336905926 bayes_pls_golite062009
  • snoRNA binding
    		•  1.1873470464264 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • receptor activity
    		•  1.12819778129653 bayes_pls_golite062009
  • transcription factor activity
    		•  1.08768505897883 bayes_pls_golite062009
  • microtubule plus-end binding
    		•  1.01166033978052 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • signal transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • protein transporter activity
    		•  0.964340340346761 bayes_pls_golite062009
  • angiotensin receptor binding
    		•  0.920323565472959 bayes_pls_golite062009
  • type 1 angiotensin receptor binding
    		•  0.920323565472959 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.734793983890004 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  0.700626674902544 bayes_pls_golite062009
  • histone binding
    		•  0.685319917508843 bayes_pls_golite062009
  • transcription factor binding
    		•  0.489473003915035 bayes_pls_golite062009
  • dynein intermediate chain binding
    		•  0.443846546939402 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.426429095658617 bayes_pls_golite062009
  • kinase activity
    		•  0.387572734234845 bayes_pls_golite062009
  • receptor binding
    		•  0.316169754698691 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.30761651528651 bayes_pls_golite062009
  • protein kinase activity
    		•  0.229242350006544 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.226335610368636 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.161639372576406 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.118975415284669 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00585398682921312 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  0.00335766408304172 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  2.08918220528461 bayes_pls_golite062009
  • hydrolase activity
    		•  1.28518277085799 bayes_pls_golite062009
  • catalytic activity
    		•  1.00900109067915 bayes_pls_golite062009
  • peptide binding
    		•  0.935271307264137 bayes_pls_golite062009
  • protein binding
    		•  0.79136605420755 bayes_pls_golite062009
  • peptidase activity
    		•  0.432758891186532 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.371207540169179 bayes_pls_golite062009
  • dipeptidyl-peptidase activity
    		•  0.321248124100964 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.125785958315692 bayes_pls_golite062009
  • protein homodimerization activity
    		•  0.108476440668653 bayes_pls_golite062009
    3
    Term Confidence Notes
  • binding
    		•  2.64850159998065 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.36976362065221 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.05265117445838 bayes_pls_golite062009
  • DNA binding
    		•  1.96740629247708 bayes_pls_golite062009
  • protein binding
    		•  1.51322932625387 bayes_pls_golite062009
  • peptide binding
    		•  1.46005161552536 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.40841220242471 bayes_pls_golite062009
  • transcription factor activity
    		•  1.22524361832616 bayes_pls_golite062009
  • receptor activity
    		•  1.20519296797117 bayes_pls_golite062009
  • RNA binding
    		•  1.17447432946881 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.13603983412087 bayes_pls_golite062009
  • signal transducer activity
    		•  1.13603983412087 bayes_pls_golite062009
  • signal sequence binding
    		•  0.791153798439582 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  0.597017459591015 bayes_pls_golite062009
  • transcription factor binding
    		•  0.447234745044969 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  0.36489074781643 bayes_pls_golite062009
  • enzyme binding
    		•  0.335436488591595 bayes_pls_golite062009
  • peroxisome targeting sequence binding
    		•  0.209148717913838 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.201108481303385 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.177518071994821 bayes_pls_golite062009
  • transferase activity
    		•  0.157308242400253 bayes_pls_golite062009
  • receptor binding
    		•  0.140308019811153 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.0645101607447045 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0514451541233234 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.0290076512914955 bayes_pls_golite062009
  • acetyltransferase activity
    		•  0.0217632433282022 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.0194562796536073 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle