| Protein: | COB23_ARATH |
| Organism: | Arabidopsis thaliana |
| Length: | 909 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COB23_ARATH.
| Description | E-value | Query Range |
Subject Range |
|
|
736.0 | [0..1] | [903..1] |
|
Region A: Residues: [1-226] |
1 11 21 31 41 51
| | | | | |
1 MPLRLDIKRK FAQRSERVKS VDLHPTEPWI LASLYSGTVC IWNYQTQTIT KSFEVTELPV 60
61 RSAKFIPRKQ WVVAGADDMY IRVYNYNTMD KVKVFEAHSD YIRCVAVHPT LPYVLSSSDD 120
121 MLIKLWDWEN GWACTQIFEG HSHYVMQVVF NPKDTNTFAS ASLDRTIKIW NLGSPDPNFT 180
181 LDAHQKGVNC VDYFTGGDKP YLITGSDDHT AKVWDYQTKS CVQTLD
|
| Detection Method: |  |
| Confidence: | 85.522879 |
| Match: | 1vyhC |
| Description: | PAF-AH Holoenzyme: Lis1/Alfa2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| histone methyltransferase activity (H3-K4 specific) | 4.71992275913384 | bayes_pls_golite062009 |
| GTPase activity | 4.02994814377904 | bayes_pls_golite062009 |
| 3.48848918010996 | bayes_pls_golite062009 | |
| actin binding | 3.31804728298431 | bayes_pls_golite062009 |
| S-adenosylmethionine-dependent methyltransferase activity | 3.25521258308263 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 3.1056443224755 | bayes_pls_golite062009 |
| tubulin binding | 2.76945430061825 | bayes_pls_golite062009 |
| microtubule binding | 2.72684103222924 | bayes_pls_golite062009 |
| dynein binding | 2.54821997913979 | bayes_pls_golite062009 |
| binding | 2.42570478946173 | bayes_pls_golite062009 |
| transcription regulator activity | 2.3610959773142 | bayes_pls_golite062009 |
| nucleic acid binding | 2.30918780727915 | bayes_pls_golite062009 |
| transcription repressor activity | 2.29049708962212 | bayes_pls_golite062009 |
| RNA binding | 2.1927334052131 | bayes_pls_golite062009 |
| dynactin binding | 1.92897254169098 | bayes_pls_golite062009 |
| histone methyltransferase activity | 1.85632145559025 | bayes_pls_golite062009 |
| DNA binding | 1.71685536470455 | bayes_pls_golite062009 |
| actin filament binding | 1.5197243426595 | bayes_pls_golite062009 |
| structural molecule activity | 1.47448876401574 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.41752877005447 | bayes_pls_golite062009 |
| protein methyltransferase activity | 1.35170368882651 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.22384651674093 | bayes_pls_golite062009 |
| protein binding | 1.21879977456466 | bayes_pls_golite062009 |
| transporter activity | 1.21549336905926 | bayes_pls_golite062009 |
| snoRNA binding | 1.1873470464264 | bayes_pls_golite062009 |
| lysine N-methyltransferase activity | 1.15313682561559 | bayes_pls_golite062009 |
| protein-lysine N-methyltransferase activity | 1.15313682561559 | bayes_pls_golite062009 |
| histone-lysine N-methyltransferase activity | 1.15313682561559 | bayes_pls_golite062009 |
| receptor activity | 1.12819778129653 | bayes_pls_golite062009 |
| transcription factor activity | 1.08768505897883 | bayes_pls_golite062009 |
| microtubule plus-end binding | 1.01166033978052 | bayes_pls_golite062009 |
| molecular transducer activity | 0.974380908248463 | bayes_pls_golite062009 |
| signal transducer activity | 0.974380908248463 | bayes_pls_golite062009 |
| protein transporter activity | 0.964340340346761 | bayes_pls_golite062009 |
| angiotensin receptor binding | 0.920323565472959 | bayes_pls_golite062009 |
| type 1 angiotensin receptor binding | 0.920323565472959 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.734793983890004 | bayes_pls_golite062009 |
| G-protein-coupled receptor binding | 0.700626674902544 | bayes_pls_golite062009 |
| histone binding | 0.685319917508843 | bayes_pls_golite062009 |
| transcription factor binding | 0.489473003915035 | bayes_pls_golite062009 |
| dynein intermediate chain binding | 0.443846546939402 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.426429095658617 | bayes_pls_golite062009 |
| kinase activity | 0.387572734234845 | bayes_pls_golite062009 |
| receptor binding | 0.316169754698691 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.30761651528651 | bayes_pls_golite062009 |
| protein kinase activity | 0.229242350006544 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.226335610368636 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.161639372576406 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.118975415284669 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.00585398682921312 | bayes_pls_golite062009 |
| N-methyltransferase activity | 0.00335766408304172 | bayes_pls_golite062009 |
|
Region A: Residues: [227-639] |
1 11 21 31 41 51
| | | | | |
1 GHTHNVSAVC FHPELPIIIT GSEDGTVRIW HATTYRLENT LNYGLERVWA IGYIKSSRRV 60
61 VIGYDEGTIM VKLGREIPVA SMDSSGKIIW AKHNEIQTAN IKSIGAGYEA TDGERLPLSV 120
121 KELGTCDLYP QSLKHNPNGR FVVVCGDGEY IIYTALAWRN RSFGSGLEFV WSSEGECAVR 180
181 ESSSKIKIFS KNFQERKSIR PTFSAEKIFG GTLLAMCSND FICFYDWAEC RLIQQIDVTV 240
241 KNLYWAESGD LVAIASDTSF YILKYNRELV SSHFDSGRPT DEEGVEDAFE VLHENDERVR 300
301 TGIWVGDCFI YNNSSWKLNY CVGGEVTTMY HLDRPMYLLG YIANQSRVYL VDKEFNVIGY 360
361 TLLLSLIEYK TLVMRGDLDR ANQILPTIPK EQHNNVAHFL ESRGMIEDAL EIA
|
| Detection Method: | |
| Confidence: | 4.69897 |
| Match: | 1r9nA |
| Description: | Crystal Structure of human dipeptidyl peptidase IV in complex with a decapeptide (tNPY) at 2.3 Ang. Resolution |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.08918220528461 | bayes_pls_golite062009 |
| hydrolase activity | 1.28518277085799 | bayes_pls_golite062009 |
| catalytic activity | 1.00900109067915 | bayes_pls_golite062009 |
| peptide binding | 0.935271307264137 | bayes_pls_golite062009 |
| protein binding | 0.79136605420755 | bayes_pls_golite062009 |
| peptidase activity | 0.432758891186532 | bayes_pls_golite062009 |
| protein dimerization activity | 0.371207540169179 | bayes_pls_golite062009 |
| dipeptidyl-peptidase activity | 0.321248124100964 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 0.125785958315692 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.108476440668653 | bayes_pls_golite062009 |
|
Region A: Residues: [640-909] |
1 11 21 31 41 51
| | | | | |
1 TDPDYKFDLA IQLGRLEIAK EIAEEVQSES KWKQLGELAM SSGKLQLAED CMKYAMDLSG 60
61 LLLLYSSLGD AEGVSKLACL AKEQGKNNVA FLCLFTLGRL EDCLQLLVES NRIPEAALMA 120
121 RSYLPSKVSE IVALWREDLS KVNPKAAESL ADPEEYSNLF EDWQVALSVE ANTAETRGVY 180
181 TAAENYPSHA DKPSITLVEA FRNLQVEAEE SLENGNIDHE VAEENGHVEN EGDEEEQQEE 240
241 EVNEEEGVVD ADSTDGAVLV NGSEVLTPHP
|
| Detection Method: | |
| Confidence: | 0.97 |
| Match: | 2fbnA |
| Description: | Plasmodium falciparum putative FK506-binding protein PFL2275c, C-terminal TPR-containing domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.64850159998065 | bayes_pls_golite062009 |
| transcription regulator activity | 2.36976362065221 | bayes_pls_golite062009 |
| nucleic acid binding | 2.05265117445838 | bayes_pls_golite062009 |
| DNA binding | 1.96740629247708 | bayes_pls_golite062009 |
| protein binding | 1.51322932625387 | bayes_pls_golite062009 |
| peptide binding | 1.46005161552536 | bayes_pls_golite062009 |
| transcription repressor activity | 1.40841220242471 | bayes_pls_golite062009 |
| transcription factor activity | 1.22524361832616 | bayes_pls_golite062009 |
| receptor activity | 1.20519296797117 | bayes_pls_golite062009 |
| RNA binding | 1.17447432946881 | bayes_pls_golite062009 |
| molecular transducer activity | 1.13603983412087 | bayes_pls_golite062009 |
| signal transducer activity | 1.13603983412087 | bayes_pls_golite062009 |
| signal sequence binding | 0.791153798439582 | bayes_pls_golite062009 |
| N-acetyltransferase activity | 0.597017459591015 | bayes_pls_golite062009 |
| transcription factor binding | 0.447234745044969 | bayes_pls_golite062009 |
| N-acyltransferase activity | 0.36489074781643 | bayes_pls_golite062009 |
| enzyme binding | 0.335436488591595 | bayes_pls_golite062009 |
| peroxisome targeting sequence binding | 0.209148717913838 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.201108481303385 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.177518071994821 | bayes_pls_golite062009 |
| transferase activity | 0.157308242400253 | bayes_pls_golite062009 |
| receptor binding | 0.140308019811153 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.0645101607447045 | bayes_pls_golite062009 |
| transcription activator activity | 0.0514451541233234 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.0290076512914955 | bayes_pls_golite062009 |
| acetyltransferase activity | 0.0217632433282022 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.0194562796536073 | bayes_pls_golite062009 |
