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Protein Overview: RQL3_ARATH

General Information:
Name(s) found: RQL3_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|30690461|ref|NP_195299.2| RecQl3; ATP binding / ATP-dependent helicase/ helicase/ nucleic acid binding [Arabidopsis thaliana] [NCBI NR]
  • gi|11121447|emb|CAC14867.1| DNA Helicase [Arabidopsis thaliana] [NCBI NR]
  • ATP-dependent DNA helicase Q-like 3 OS=Arabidopsis thaliana GN=RECQL3 PE=1 SV=1 [Swiss-Prot]
  • DNA Helicase [Arabidopsis thaliana]gi|30690461|ref|NP_195299.2| DNA helicase (RECQl3) [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 DNA helicase (RECQl3) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: RecQl3 | RecQl3 (Recq-like 3); ATP binding / ATP-dependent helicase | chr4:16936238-16940177 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • DNA Helicase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ATP binding / ATP-dependent helicase/ helicase/ nucleic acid binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: RecQl3, ATRECQ3 | DEAD/DEAH box RNA helicase family protein | chr4:16936233-16940172 FORWARD LENGTH=713 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 713 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: DNA recombination [IEA]
    Molecular Function: ATP binding [ISS]
    ATP-dependent helicase activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKSPLPVQN VQSSDKNVAG KEALVKLLRW HFGHADFRGK QLEAIQAVVS GRDCFCLMPT  60
   61 GGGKSICYQI PALAKPGIVL VVSPLIALME NQVMALKEKG IAAEYLSSTQ ATHVKNKIHE 120
  121 DLDSGKPSVR LLYVTPELIA TKGFMLKLRK LHSRGLLNLI AIDEAHCISS WGHDFRPSYR 180
  181 QLSTLRDSLA DVPVLALTAT AAPKVQKDVI DSLNLRNPLV LKSSFNRPNI FYEVRYKDLL 240
  241 DNAYTDLGNL LKSCGNICAI IYCLERTTCD DLSVHLSSIG ISSAAYHAGL NSKMRSTVLD 300
  301 DWLSSKKQII VATVAFGMGI DKKDVRMVCH FNIPKSMESF YQESGRAGRD QLPSRSVLYY 360
  361 GVDDRKKMEY LLRNSENKKS SSSKKPTSDF EQIVTYCEGS GCRRKKILES FGEEFPVQQC 420
  421 KKTCDACKHP NQVAHCLEEL MTTASRRHNS SRIFITSSNN KTNEGQYSEF WNRNEDGSNS 480
  481 NEEISDSDDA TEAANSVTGP KLSKKLGLDE KLVLLEQAEE KYYERNKQVK KSEKNAISEA 540
  541 LRDSSKQRLL DALTRVLQLL ACVEEIDSQK GSEFLENECY RKYSKAGKSF YYSQIASTVR 600
  601 WLGTASRDEL MTRLSSVVSL AREQEPLEEP LLATEPVENI EEEDDGKTNT VESRVDEPTQ 660
  661 ELVVSPILSP IRLPQVPSFS EFVNRRKIKQ NTLIDKSSEG FDDKKPAKIM KLQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..527] PSI-BLAST 100.0 Structure of the RecQ Catalytic Core
    2 View Details [528..713] PSI-BLAST 12.09691 Crystal structure of SecA:ADP in an open conformation from Bacillus Subtilis

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation initiation factor activity
    		•  7.79457008386475 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  4.98637553020315 bayes_pls_golite062009
  • translation regulator activity
    		•  4.94658029227343 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  4.56509805974548 bayes_pls_golite062009
  • structural molecule activity
    		•  3.58406348799895 bayes_pls_golite062009
  • RNA cap binding
    		•  3.05696024978364 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.13284212711072 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.11222585187695 bayes_pls_golite062009
  • DNA binding
    		•  1.7904783386531 bayes_pls_golite062009
  • helicase activity
    		•  1.70242731830224 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.68903321260301 bayes_pls_golite062009
  • RNA binding
    		•  1.60613159109369 bayes_pls_golite062009
    		• 1.44426272235796 bayes_pls_golite062009
  • RNA helicase activity
    		•  1.42791449104435 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  1.39335733374328 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  1.36724390116598 bayes_pls_golite062009
  • microtubule motor activity
    		•  1.30090199952739 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.2155186842031 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.20315703345493 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  1.05408274676326 bayes_pls_golite062009
  • motor activity
    		•  1.03253378953548 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.72881469450553 bayes_pls_golite062009
  • transcription factor activity
    		•  0.603758349693077 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.5886142102548 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.569910969126728 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.568840867400671 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.568779924702229 bayes_pls_golite062009
  • nucleotide binding
    		•  0.564275755355315 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.406600732518248 bayes_pls_golite062009
  • four-way junction helicase activity
    		•  0.26252931460003 bayes_pls_golite062009
  • ATP binding
    		•  0.1860481660648 bayes_pls_golite062009
  • exodeoxyribonuclease V activity
    		•  0.185603938981231 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.152859582615242 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.147579541298736 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.138615225841109 bayes_pls_golite062009
  • mismatched DNA binding
    		•  0.13366911641814 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.113504049290503 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.111293884322157 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle