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Protein Overview: gi|51247632

General Information:
Name(s) found: gi|51247632 [NCBI NR]
Description(s) found:
Found 2 descriptions.
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  • gi|51247632|pdb|1TDH|A Chain A, Crystal Structure Of Human Endonuclease Viii-Like 1 (Neil1) [NCBI NR]
    • Organism: Homo sapiens
    Length: 364 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPEGPELHLA SQFVNEACRA LVFGGCVEKS SVSRNPEVPF ESSAYRISAS ARGKELRLIL  60
   61 SPLPGAQPQQ EPLALVFRFG MSGSFQLVPR EELPRHAHLR FYTAPPGPRL ALCFVDIRRF 120
  121 GRWDLGGKWQ PGRGPCVLQE YQQFRESVLR NLADKAFDRP ICEALLDQRF FNGIGNYLRA 180
  181 EILYRLKIPP FEKARSVLEA LQQHRPSPEL TLSQKIRTKL QNPDLLELCH SVPKEVVQLG 240
  241 GRGYGSESGE EDFAAFRAWL RCYGMPGMSS LQDRHGRTIW FQGDPGPLAP KGRKSRKKKS 300
  301 KATQLSPEDR VEDALPPSKA PSRTRRAKRD LPKRKGRQAA SGHCRPRKVK ADIPSLEPEG 360
  361 TSAS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. gi|112491310 gi|219109210, gi... gi|51247632 gi|56554577

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..364] PSI-BLAST 87.522879 Crystal structure of human endonuclease VIII-like 1 (NEIL1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA N-glycosylase activity
    		•  4.96603037464775 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing N-glycosyl compounds
    		•  4.42310295950282 bayes_pls_golite062009
  • oxidized base lesion DNA N-glycosylase activity
    		•  4.07532318409219 bayes_pls_golite062009
  • DNA-(apurinic or apyrimidinic site) lyase activity
    		•  4.07268074802746 bayes_pls_golite062009
  • oxidized purine base lesion DNA N-glycosylase activity
    		•  3.59184355710115 bayes_pls_golite062009
  • binding
    		•  2.76561765026195 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  2.40884427300274 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.20400142735918 bayes_pls_golite062009
  • DNA binding
    		•  2.18702281581791 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.04270847321412 bayes_pls_golite062009
  • hydrolase activity
    		•  1.74627738237592 bayes_pls_golite062009
  • transcription factor activity
    		•  1.44182975349714 bayes_pls_golite062009
  • protein binding
    		•  1.29473277650963 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.71242082351425 bayes_pls_golite062009
  • transcription activator activity
    		•  0.612819891085 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.51536225088963 bayes_pls_golite062009
  • transcription factor binding
    		•  0.40850395411512 bayes_pls_golite062009
  • ligand-dependent nuclear receptor activity
    		•  0.39641256766754 bayes_pls_golite062009
  • catalytic activity
    		•  0.101795606736461 bayes_pls_golite062009
  • lyase activity
    		•  0.0836281676510939 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0775494030801263 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle