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Protein Overview: gi|49258498

General Information:
Name(s) found: gi|49258498 [NCBI NR]
Description(s) found:
Found 2 descriptions.
SHOW ALL
  • gi|49258498|pdb|1PZL|A Chain A, Crystal Structure Of Hnf4a Lbd In Complex With The Ligand And The Coactivator Src-1 Peptide [NCBI NR]
    • Organism: Homo sapiens
    Length: 237 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSYELASLPS INALLQAEVL SRQITSPVSG INGDIRAKKI ASIADVCESM KEQLLVLVEW  60
   61 AKYIPAFCEL PLDDQVALLR AHAGEHLLLG ATKRSMVFKD VLLLGNDYIV PRHCPELAEM 120
  121 SRVSIRILDE LVLPFQELQI DDNEYAYLKA IIFFDPDAKG LSDPGKIKRL RSQVQVSLED 180
  181 YINDRQYDSR GRFGELLLLL PTLQSITWQM IEQIQFIKLF GMAKIDNLLQ EMLLGGS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. gi|112491310 gi|226438235, gi... gi|49258498 gi|56554577

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..237] PSI-BLAST 47.39794 Crystal structure of HNF4a LBD in complex with the ligand and the coactivator SRC-1 peptide

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  3.96722324965091 bayes_pls_golite062009
  • DNA binding
    		•  3.25939553877631 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.16396885393239 bayes_pls_golite062009
  • transcription activator activity
    		•  2.6892852470567 bayes_pls_golite062009
  • transcription factor activity
    		•  2.56099230851339 bayes_pls_golite062009
  • binding
    		•  2.51356324019445 bayes_pls_golite062009
  • protein binding
    		•  2.49676963514373 bayes_pls_golite062009
  • ligand-dependent nuclear receptor activity
    		•  2.20144353900307 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.1684625121246 bayes_pls_golite062009
  • signal transducer activity
    		•  1.57315744720763 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.57315744720763 bayes_pls_golite062009
  • receptor activity
    		•  1.28597420456904 bayes_pls_golite062009
  • transcription factor binding
    		•  0.78455053961808 bayes_pls_golite062009
  • steroid hormone receptor activity
    		•  0.71366308307673 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.49585672359082 bayes_pls_golite062009
  • catalytic activity
    		•  0.477341996033689 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.36233153809872 bayes_pls_golite062009
  • retinoic acid receptor activity
    		•  0.26050147400703 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle