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Protein Overview: GPX1_MOUSE

General Information:
Name(s) found: GPX1_MOUSE [Swiss-Prot]
Description(s) found:
Found 16 descriptions.
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  • Glutathione peroxidase 1 OS=Mus musculus GN=Gpx1 PE=1 SV=2 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 201 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN]
    soluble fraction [UNKNOWN]
    cytoplasm [IEA]
    mitochondrion [IDA][IMP]
    Biological Process: cell proliferation [IMP]
    heart contraction [IMP]
    response to wounding [IMP]
    response to lipid hydroperoxide [UNKNOWN]
    triglyceride metabolic process [IMP]
    vasodilation [IMP]
    response to xenobiotic stimulus [IMP]
    fat cell differentiation [IMP]
    regulation of neuron apoptosis [IMP]
    response to toxin [IMP]
    skeletal muscle tissue regeneration [IMP]
    sensory perception of sound [IMP]
    response to oxidative stress [IGI][IMP]
    endothelial cell development [IMP]
    induction of apoptosis [IMP]
    skeletal muscle fiber development [IMP]
    response to symbiotic bacterium [IGI]
    apoptosis [IMP]
    protein amino acid oxidation [IMP]
    response to gamma radiation [IGI]
    interaction with symbiont [IGI]
    angiogenesis involved in wound healing [IMP]
    response to hydroperoxide [IMP]
    induction of apoptosis by oxidative stress [IMP]
    response to hydrogen peroxide [IMP]
    blood vessel endothelial cell migration [IMP]
    response to reactive oxygen species [IMP]
    hydrogen peroxide catabolic process [UNKNOWN][IMP]
    negative regulation of inflammatory response to antigenic stimulus [IGI]
    glutathione metabolic process [UNKNOWN]
    negative regulation of apoptosis [IMP]
    temperature homeostasis [IGI]
    lipid metabolic process [IMP]
    myoblast proliferation [IMP]
    myotube differentiation [IMP]
    oxidation reduction [IEA]
    positive regulation of protein kinase B signaling cascade [IMP]
    Molecular Function: peroxidase activity [IEA]
    phospholipid-hydroperoxide glutathione peroxidase activity [UNKNOWN]
    glutathione peroxidase activity [UNKNOWN][IDA][IMP]
    selenium binding [UNKNOWN]
    glutathione binding [UNKNOWN]
    oxidoreductase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCAARLSAAA QSTVYAFSAR PLTGGEPVSL GSLRGKVLLI ENVASLUGTT IRDYTEMNDL  60
   61 QKRLGPRGLV VLGFPCNQFG HQENGKNEEI LNSLKYVRPG GGFEPNFTLF EKCEVNGEKA 120
  121 HPLFTFLRNA LPTPSDDPTA LMTDPKYIIW SPVCRNDIAW NFEKFLVGPD GVPVRRYSRR 180
  181 FRTIDIEPDI ETLLSQQSGN S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle