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Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. Catalysis of the reaction: a lipid hydroperoxide + 2 reduced glutathione = 2 H2O + lipid + 2 oxidized glutathione. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: phospholipid-hydroperoxide glutathione peroxidase activity
Acc: GO:0047066
Aspect: Molecular Function
Desc: Catalysis of the reaction: a lipid hydroperoxide + 2 reduced glutathione = 2 H2O + lipid + 2 oxidized glutathione.
Synonyms:
  • glutathione:lipid-hydroperoxide oxidoreductase activity
  • peroxidation-inhibiting protein: peroxidase, glutathione (phospholipid hydroperoxide-reducing)
  • peroxidation-inhibiting protein activity
  • hydroperoxide glutathione peroxidase activity
  • phospholipid hydroperoxide glutathione peroxidase activity
  • PHGPX
Proteins in PDR annotated with:
   This term: 10 [Search]
   Term or descendants: 10 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047066 - phospholipid-hydroperoxide glutathione peroxidase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle