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The process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. The regrowth of a lost or destroyed body part, such as an organ or tissue. The process whereby a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. The regrowth of lost or destroyed tissues. The process whereby a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. The regrowth of muscle tissue to repair injured or damaged muscle fibers in the postnatal stage at the neuromuscular junction. Regeneration of neuromuscular junctions occurs in an orderly way and relies on communication between nerve and muscle. Skeletal myofibers regenerate after injury and form neuro-muscular junctions with motor axons similar to normal ones. Regenerating myofibers develop within the basal lamina sheaths (satellite cells) of original myofibers. Any process that modulates the frequency, rate or extent of skeletal muscle. The series of events that restore integrity to a damaged tissue, following an injury. Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle regeneration. The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. Any process that activates or increase the rate of skeletal muscle regeneration. The multiplication or reproduction of myoblast cells, resulting in the expansion of the cell population. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage. The process essential to maintain a ready source of satellite cells. It consists of the return of activated satellite cells to a quiescent state after proliferation to replenish the satellite cell pool. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. The process whereby a relatively unspecialized satellite cell acquires specialized features of a myoblast cell. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: skeletal muscle tissue regeneration
Acc: GO:0043403
Aspect: Biological Process
Desc: The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.
Synonyms:
  • myofiber turnover
Proteins in PDR annotated with:
   This term: 21 [Search]
   Term or descendants: 33 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043403 - skeletal muscle tissue regeneration (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle