| Protein: | gi|45447058, gi|... |
| Organism: | Drosophila melanogaster |
| Length: | 541 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|45447058, gi|....
| Description | E-value | Query Range |
Subject Range |
|
|
457.0 | [0..22] | [541..41] |
|
Region A: Residues: [1-365] |
1 11 21 31 41 51
| | | | | |
1 MCRVPCIKFL EPAVSNCANS QMIVQSVLME LVFHSCAAGP HEKRLLHALL DNYNSLERPV 60
61 VNESDPLQLS FGLTLMQIID VDEKNQLLIT NIWLKLEWND MNLRWNSSEF GGVRDLRIPP 120
121 HRLWKPDVLM YNSADEGFDG TYATNVVVRN NGSCLYVPPG IFKSTCKIDI TWFPFDDQRC 180
181 EMKFGSWTYD GFQLDLQLQD EAGGDISSFI TNGEWDLLGV PGKRNEIYYN CCPEPYIDIT 240
241 FAILIRRKTL YYFFNLIVPC VLIASMALLG FTLPPDSGEK LSLGVTILLS LTVFLNMVAE 300
301 TMPATSDAVP LLGTYFNCIM FMVASSVVST ILILNYHHRN PDTHEMSEWI RVIFLYWLPC 360
361 ILRMQ
|
| Detection Method: |  |
| Confidence: | 79.0 |
| Match: | 2bg9A |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [366-541] |
1 11 21 31 41 51
| | | | | |
1 RPGQVGYECP PPPSSSSSSA SGEKKQQIQN VELKERSSKS LLANVLDIDD DFRCNHRCAS 60
61 ATLPHQPTYY RTMYRQGDDG SVGPVGPAGP VVDGRLHEAI SHTCLTSSAE YELALILKEL 120
121 RWITEQLKKE DETSDITRDW KFAAMVVDRL CLIIFTLFTI IATLAVLFSA PHFIFP
|
| Detection Method: | |
| Confidence: | 43.69897 |
| Match: | 1oedB |
| Description: | Acetylcholine receptor protein, beta chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| acetylcholine binding | 13.9752632471881 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 13.7533645836795 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 13.1511875247796 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 11.9525876011069 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| cation channel activity | 11.7442066737514 | bayes_pls_golite062009 |
| ion channel activity | 11.1753684044644 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 11.0903806681397 | bayes_pls_golite062009 |
| channel activity | 11.0903806681397 | bayes_pls_golite062009 |
| gated channel activity | 11.0397691626728 | bayes_pls_golite062009 |
| substrate-specific channel activity | 10.9375522860542 | bayes_pls_golite062009 |
| ligand-gated channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| amine binding | 9.11982124959723 | bayes_pls_golite062009 |
| chloride channel regulator activity | 9.10587892909341 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 7.22265353460749 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 7.19173677417054 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 6.7875346065164 | bayes_pls_golite062009 |
| transmembrane receptor activity | 5.4080353535498 | bayes_pls_golite062009 |
| receptor activity | 5.11329651194787 | bayes_pls_golite062009 |
| transporter activity | 5.11262082564788 | bayes_pls_golite062009 |
| transmembrane transporter activity | 5.03439798256257 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 4.91314874981447 | bayes_pls_golite062009 |
| neurotransmitter binding | 4.25797760547212 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 4.15404686068319 | bayes_pls_golite062009 |
| signal transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| molecular transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| binding | 2.4916526322278 | bayes_pls_golite062009 |
| adenylate cyclase binding | 2.44136378171826 | bayes_pls_golite062009 |
| beta-amyloid binding | 2.25766805801029 | bayes_pls_golite062009 |
| 1.68370717591127 | bayes_pls_golite062009 | |
| channel regulator activity | 1.66978990310631 | bayes_pls_golite062009 |
| protein binding | 1.45740893920165 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.42422063123689 | bayes_pls_golite062009 |
| serotonin binding | 1.33584589886834 | bayes_pls_golite062009 |
| serotonin-activated cation-selective channel activity | 1.31324203158511 | bayes_pls_golite062009 |
| toxin binding | 1.03329843925063 | bayes_pls_golite062009 |
| drug binding | 0.64715018605883 | bayes_pls_golite062009 |
| kinase binding | 0.365355763029699 | bayes_pls_golite062009 |
| protein kinase binding | 0.350601457777817 | bayes_pls_golite062009 |
