| Protein: | robo-PB |
| Organism: | Drosophila melanogaster |
| Length: | 1429 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for robo-PB.
| Description | E-value | Query Range |
Subject Range |
|
|
848.0 | [0..35] | [1429..1] |
|
Region A: Residues: [1-88] |
1 11 21 31 41 51
| | | | | |
1 MPPRLHMTQK QRQNDRRCIG SSVESSLQQH QHHKMHPMHP ENHAIARSTS TTNNPSRSRS 60
61 SRMWLLPAWL LLVLVASNGL PAVRGQYQ
|
| Detection Method: |  |
| Confidence: | 61.39794 |
| Match: | 1cs6A |
| Description: | Axonin-1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [89-187] |
1 11 21 31 41 51
| | | | | |
1 SPRIIEHPTD LVVKKNEPAT LNCKVEGKPE PTIEWFKDGE PVSTNEKKSH RVQFKDGALF 60
61 FYRTMQGKKE QDGGEYWCVA KNRVGQAVSR HASLQIAVL
|
| Detection Method: | |
| Confidence: | 43.522879 |
| Match: | 2v9qA |
| Description: | No description for 2v9qA was found. |
|
Region A: Residues: [188-583] |
1 11 21 31 41 51
| | | | | |
1 RDDFRVEPKD TRVAKGETAL LECGPPKGIP EPTLIWIKDG VPLDDLKAMS FGASSRVRIV 60
61 DGGNLLISNV EPIDEGNYKC IAQNLVGTRE SSYAKLIVQV KPYFMKEPKD QVMLYGQTAT 120
121 FHCSVGGDPP PKVLWKKEEG NIPVSRARIL HDEKSLEISN ITPTDEGTYV CEAHNNVGQI 180
181 SARASLIVHA PPNFTKRPSN KKVGLNGVVQ LPCMASGNPP PSVFWTKEGV STLMFPNSSH 240
241 GRQHVAADGT LQITDVRQED EGYYVCSAFS VVDSSTVRVF LQVSSLDERP PPIIQIGPAN 300
301 QTLPKGSVAT LPCRATGNPS PRIKWFHDGH AVQAGNRYSI IQGSSLRVDD LQLSDSGTYT 360
361 CTASGERGET SWAATLTVEK PGSTSLHRAA DPSTYP
|
| Detection Method: | |
| Confidence: | 41.39794 |
| Match: | 1bihA |
| Description: | Hemolin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 6.64811984458494 | bayes_pls_golite062009 |
| alpha-actinin binding | 5.77350124471385 | bayes_pls_golite062009 |
| actinin binding | 5.69539760434923 | bayes_pls_golite062009 |
| structural constituent of muscle | 4.93896503565413 | bayes_pls_golite062009 |
| binding | 3.17641566810715 | bayes_pls_golite062009 |
| receptor activity | 2.6260148704617 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.26083981067854 | bayes_pls_golite062009 |
| molecular transducer activity | 2.26075587783872 | bayes_pls_golite062009 |
| signal transducer activity | 2.26075587783872 | bayes_pls_golite062009 |
| protein binding | 2.22855404705168 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 1.8360014271135 | bayes_pls_golite062009 |
| fibroblast growth factor 1 binding | 1.70428381075539 | bayes_pls_golite062009 |
| antigen binding | 1.63189745559168 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.58610597245454 | bayes_pls_golite062009 |
| actin binding | 1.42681407553255 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 1.36789541796983 | bayes_pls_golite062009 |
| protein kinase activity | 1.36635494500222 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32330470851159 | bayes_pls_golite062009 |
| DNA binding | 1.19412627500732 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.17845072849922 | bayes_pls_golite062009 |
| transcription regulator activity | 1.16252234499274 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.02286631988334 | bayes_pls_golite062009 |
| fibroblast growth factor binding | 0.955166176899348 | bayes_pls_golite062009 |
| kinase activity | 0.929878054374821 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.878595022643164 | bayes_pls_golite062009 |
| olfactory receptor activity | 0.76374091031142 | bayes_pls_golite062009 |
| actin filament binding | 0.760856470721016 | bayes_pls_golite062009 |
| peptide antigen binding | 0.75156669330877 | bayes_pls_golite062009 |
| IgG binding | 0.68435857661103 | bayes_pls_golite062009 |
| myosin heavy chain binding | 0.66378995104464 | bayes_pls_golite062009 |
| receptor binding | 0.632627479346393 | bayes_pls_golite062009 |
| titin binding | 0.599892148302011 | bayes_pls_golite062009 |
| integrin binding | 0.599569390248921 | bayes_pls_golite062009 |
| structural molecule activity | 0.567620977360967 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.564762108830441 | bayes_pls_golite062009 |
| transcription factor activity | 0.54549168007511 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 0.51084773288725 | bayes_pls_golite062009 |
| protein complex binding | 0.43131084085213 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 0.318890055375093 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.310661919610704 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.0579247757286607 | bayes_pls_golite062009 |
| transferase activity | 0.053007146193305 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.0182656128082201 | bayes_pls_golite062009 |
|
Region A: Residues: [584-647] |
1 11 21 31 41 51
| | | | | |
1 APPGTPKVLN VSRTSISLRW AKSQEKPGAV GPIIGYTVEY FSPDLQTGWI VAAQRVGDTQ 60
61 VTIS
|
| Detection Method: | |
| Confidence: | 44.154902 |
| Match: | 2nziA |
| Description: | No description for 2nziA was found. |
|
Region A: Residues: [648-691] |
1 11 21 31 41 51
| | | | | |
1 GLTPGTSYVF LVRAENTQGI SVPSGLSNTI KTIEADFDAA SAND
|
| Detection Method: | |
| Confidence: | 2.82 |
| Match: | 1uemA |
| Description: | Solution Structure of the First Fibronectin Type III domain of human KIAA1568 Protein |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [692-798] |
1 11 21 31 41 51
| | | | | |
1 LSAARTLLTG KSVELIDASA INASAVRLEW MLHVSADEKY VEGLRIHYKD ASVPSAQYHS 60
61 ITVMDASAES FVVGNLKKYT KYEFFLTPFF ETIEGQPSNS KTALTYE
|
| Detection Method: | |
| Confidence: | 10.522879 |
| Match: | 2edxA |
| Description: | No description for 2edxA was found. |
|
Region A: Residues: [799-993] |
1 11 21 31 41 51
| | | | | |
1 DVPSAPPDNI QIGMYNQTAG WVRWTPPPSQ HHNGNLYGYK IEVSAGNTMK VLANMTLNAT 60
61 TTSVLLNNLT TGAVYSVRLN SFTKAGDGPY SKPISLFMDP THHVHPPRAH PSGTHDGRHE 120
121 GQDLTYHNNG NIPPGDINPT THKKTTDYLS GPWLMVLVCI VLLVLVISAA ISMVYFKRKH 180
181 QMTKELGHLS VVSDN
|
| Detection Method: | |
| Confidence: | 20.0 |
| Match: | 1x5hA |
| Description: | The solution structure of the third fibronectin type III domain of human Neogenin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| receptor activity | 3.28625508322269 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.25570370343123 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| signal transducer activity | 2.84396290475308 | bayes_pls_golite062009 |
| molecular transducer activity | 2.84396290475308 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| cytokine binding | 2.06262704705789 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| growth factor binding | 1.74816715186275 | bayes_pls_golite062009 |
| cytokine receptor activity | 1.56546704499749 | bayes_pls_golite062009 |
| interleukin-6 binding | 1.53073516901486 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 1.53073516901486 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| receptor binding | 1.31676259534833 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| growth hormone receptor activity | 0.840187286074179 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 0.71036287694215 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| ankyrin binding | 0.56921114104552 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| transferase activity | 0.432850266451294 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| peptide hormone binding | 0.31580518221542 | bayes_pls_golite062009 |
| heparin binding | 0.20390437111575 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| protease binding | 0.10146157270108 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 0.0645383199290401 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.00424319283373897 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.00424319283373897 | bayes_pls_golite062009 |
|
Region A: Residues: [994-1157] |
1 11 21 31 41 51
| | | | | |
1 EITALNINSK ESLWIDHHRG WRTADTDKDS GLSESKLLSH VNSSQSNYNN SDGGTDYAEV 60
61 DTRNLTTFYN CRKSPDNPTP YATTMIIGTS SSETCTKTTS ISADKDSGTH SPYSDAFAGQ 120
121 VPAVPVVKSN YLQYPVEPIN WSEFLPPPPE HPPPSSTYGY AQGS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1158-1429] |
1 11 21 31 41 51
| | | | | |
1 PESSRKSSKS AGSGISTNQS ILNASIHSSS SGGFSAWGVS PQYAVACPPE NVYSNPLSAV 60
61 AGGTQNRYQI TPTNQHPPQL PAYFATTGPG GAVPPNHLPF ATQRHAASEY QAGLNAARCA 120
121 QSRACNSCDA LATPSPMQPP PPVPVPEGWY QPVHPNSHPM HPTSSNHQIY QCSSECSDHS 180
181 RSSQSHKRQL QLEEHGSSAK QRGGHHRRRA PVVQPCMESE NENMLAEYEQ RQYTSDCCNS 240
241 SREGDTCSCS EGSCLYAEAG EPAPRQMTAK NT
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
