YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: dve-PB
Organism: Drosophila melanogaster
Length: 780 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dve-PB.

Description E-value Query
Range
Subject
Range
dve-PA - The gene defective proventriculus is referred to in FlyBase by the symbol Dmel\dve (CG5799, FBgn0020...
627.0 [0..6] [780..250]

Back

Predicted Domain #1
Region A:
Residues: [1-211]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLEEAKSLPL HCVVESVHSL HASLTIDTRQ PWKRRPNIET DSYVIIAAAT PWSEIVQTAL  60
   61 QRLGYSQEVA NTARGSLIIK HWKPIPLEQI SDNPAVPVSD IVGELTSVIT LRIVILRPKT 120
  121 SPFGEIKDKL LKLLVLQSHA VLRSTGCPLD EVTLSQICRS SHQNTYALPG GEISDELRRK 180
  181 FDQWWSNQLS PQATAMTPKM LPFMTGPSAV P

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [212-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPVAVPGEMD FPVGTAMAAA AAAAAHAAAA GGAAGGNPLG SMGSRESLLL ANEAAHHAGA  60
   61 GQAPGPGHHG SMLVHPMHAS MHH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [295-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HHHHGGGGGH GPPYPNQKTR MRTSFDPEME LPKLQKWFAD NPHPSRQQIQ TYVVQLNALE  60
   61 SRRGRKPLDV NNVVYWFKNA RAAQKRAEMR GGSLGSAI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.63
Match: 2da6A
Description: No description for 2da6A was found.

Predicted Domain #4
Region A:
Residues: [393-482]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SALGHAAMNG YLSQHAPLGQ NSSSSAGSQP MSMGNLSMSH DYLKSPLSLK SEDIDTMSQH  60
   61 SDDMDEEQSR PNTPQLPLSL TTHERHRSSP 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [483-652]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LMDEDEDEAG EQQQPQEAKS DGMNGSVKDE ERQEKSRDEL QDNEKENSNG EDRHLDADAQ  60
   61 MEASSNLNNN HNNSSLHIEQ EVGSTPKRST PKEEDDDLDM DEDEEDNEND ASHLDEFRSP 120
  121 SPDLAGGVVP HKDQLPFPMV PNSMFSQSFM YMSHYIPAFG QAAAGHPHHH 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [653-780]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAAAAAAAGI QPNALMGGGG LNLSSISNEE RRKRNRTFID PVTEVPKLEQ WFAMNTHPSH  60
   61 NLILKYTEDL NTMPYRQKFP RLESKNVQFW FKNRRAKCKR LKMSLYDSNQ CAQLGGLGSF 120
  121 VPKYEERD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.09691
Match: 1fjlA
Description: Paired protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.26183812259792 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.14886080629275 bayes_pls_golite062009
chromatin binding 1.04132983826241 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle