Protein Overview: dve-PA

General Information:
Name(s) found:	dve-PA / FBpp0071689 [FlyBase]
Description(s) found: Found 21 descriptions. SHOW ALL	The gene defective proventriculus is referred to in FlyBase by the symbol Dmel\dve (CG5799, FBgn0020307). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18131468..18173982. It has the cytological map location 58D2. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity; AT DNA binding. There is experimental evidence that it is involved in the biological process</span>: imaginal disc-derived wing morphogenesis; midgut development. 32 alleles are reported. The phenotypes of these alleles are annotated with: proventriculus inner layer; dorsal mesothoracic disc; cuprophilic cell; proventriculus outer layer; wing. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1024 amino acids
Gene Ontology:
Cellular Component:	nucleus [NAS]
Biological Process:	midgut development [IMP] imaginal disc-derived wing morphogenesis [IMP] regulation of transcription, DNA-dependent [IEA][ISS] regulation of transcription [IEA][TAS]
Molecular Function:	transcription factor activity [ISS][NAS][TAS] AT DNA binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFQSAMETF AEAWVAANAG QQSQALALTR AVNAAAVVAS ANAKSPNASS SASASLADLA  60
   61 VKKEHSISPP HSVVSVGVGV AGEDQHRRSS LQGVQEKLTQ LQMQQQHHQQ QQQQQQQQQQ 120
  121 QHQQQQQHHH HQQQAQQAGA GVGSGELAGR RSSEGTPPTA HPPTNSEGQA LSSSTASSSQ 180
  181 NATPKSDRER ERERERDREE RVERGSISCL PPAALGMAVG VQQAQHQEKL LSHPALDSRR 240
  241 EFDVSKVNPK SLPLHCVVES VHSLHASLTI DTRQPWKRRP NIETDSYVII AAATPWSEIV 300
  301 QTALQRLGYS QEVANTARGS LIIKHWKPIP LEQISDNPAV PVSDIVGELT SVITLRIVIL 360
  361 RPKTSPFGEI KDKLLKLLVL QSHAVLRSTG CPLDEVTLSQ ICRSSHQNTY ALPGGEISDE 420
  421 LRRKFDQWWS NQLSPQATAM TPKMLPFMTG PSAVPVPVAV PGEMDFPVGT AMAAAAAAAA 480
  481 HAAAAGGAAG GNPLGSMGSR ESLLLANEAA HHAGAGQAPG PGHHGSMLVH PMHASMHHHH 540
  541 HHGGGGGHGP PYPNQKTRMR TSFDPEMELP KLQKWFADNP HPSRQQIQTY VVQLNALESR 600
  601 RGRKPLDVNN VVYWFKNARA AQKRAEMRGG SLGSAISALG HAAMNGYLSQ HAPLGQNSSS 660
  661 SAGSQPMSMG NLSMSHDYLK SPLSLKSEDI DTMSQHSDDM DEEQSRPNTP QLPLSLTTHE 720
  721 RHRSSPLMDE DEDEAGEQQQ PQEAKSDGMN GSVKDEERQE KSRDELQDNE KENSNGEDRH 780
  781 LDADAQMEAS SNLNNNHNNS SLHIEQEVGS TPKRSTPKEE DDDLDMDEDE EDNENDASHL 840
  841 DEFRSPSPDL AGGVVPHKDQ LPFPMVPNSM FSQSFMYMSH YIPAFGQAAA GHPHHHAAAA 900
  901 AAAAGIQPNA LMGGGGLNLS SISNEERRKR NRTFIDPVTE VPKLEQWFAM NTHPSHNLIL 960
  961 KYTEDLNTMP YRQKFPRLES KNVQFWFKNR RAKCKRLKMS LYDSNQCAQL GGLGSFVPKY1020
 1021 EERD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
binding	2.40096962515027	bayes_pls_golite062009
transcription regulator activity	2.15398264148864	bayes_pls_golite062009
nucleic acid binding	1.95513305822187	bayes_pls_golite062009
DNA binding	1.80079581406991	bayes_pls_golite062009
transcription factor activity	1.15427978494805	bayes_pls_golite062009
protein binding	0.757492117682468	bayes_pls_golite062009

Term	Confidence	Notes
transcription regulator activity	4.86538715425734	bayes_pls_golite062009
DNA binding	4.40186699787632	bayes_pls_golite062009
nucleic acid binding	4.28652307290136	bayes_pls_golite062009
transcription factor activity	3.78935192723648	bayes_pls_golite062009
binding	2.92574888336072	bayes_pls_golite062009
sequence-specific DNA binding	2.15328641013602	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.00875399167309	bayes_pls_golite062009
transcription repressor activity	1.69615348178304	bayes_pls_golite062009
transcription activator activity	1.5973137667873	bayes_pls_golite062009
transcription factor binding	1.24678737091956	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.865913662624162	bayes_pls_golite062009
chromatin binding	0.82130998265632	bayes_pls_golite062009
protein binding	0.795494287543952	bayes_pls_golite062009
transcription cofactor activity	0.691780246385357	bayes_pls_golite062009
transcription corepressor activity	0.0723215858239072	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.64

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..249]	deduced	N/A	No confident structure predictions are available.
2	View Details	[250..440]	MSA	1.027931	View MSA. No confident structure predictions are available.
3	View Details	[441..538]	deduced	N/A	No confident structure predictions are available.
4	View Details	[539..873]	PSI-BLAST	4.045757	Botulinum neurotoxin
5	View Details	[874..1024]	FFAS03	4.27	TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT

Protein Overview: dve-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: