YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: dve-PB
Organism: Drosophila melanogaster
Length: 780 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dve-PB.

Description E-value Query
Range
Subject
Range
dve-PA - The gene defective proventriculus is referred to in FlyBase by the symbol Dmel\dve (CG5799, FBgn0020...
627.0 [0..6] [780..250]

Back

Predicted Domain #1
Region A:
Residues: [1-211]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLEEAKSLPL HCVVESVHSL HASLTIDTRQ PWKRRPNIET DSYVIIAAAT PWSEIVQTAL  60
   61 QRLGYSQEVA NTARGSLIIK HWKPIPLEQI SDNPAVPVSD IVGELTSVIT LRIVILRPKT 120
  121 SPFGEIKDKL LKLLVLQSHA VLRSTGCPLD EVTLSQICRS SHQNTYALPG GEISDELRRK 180
  181 FDQWWSNQLS PQATAMTPKM LPFMTGPSAV P

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [212-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPVAVPGEMD FPVGTAMAAA AAAAAHAAAA GGAAGGNPLG SMGSRESLLL ANEAAHHAGA  60
   61 GQAPGPGHHG SMLVHPMHAS MHH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [295-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HHHHGGGGGH GPPYPNQKTR MRTSFDPEME LPKLQKWFAD NPHPSRQQIQ TYVVQLNALE  60
   61 SRRGRKPLDV NNVVYWFKNA RAAQKRAEMR GGSLGSAI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.63
Match: 2da6A
Description: No description for 2da6A was found.

Predicted Domain #4
Region A:
Residues: [393-482]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SALGHAAMNG YLSQHAPLGQ NSSSSAGSQP MSMGNLSMSH DYLKSPLSLK SEDIDTMSQH  60
   61 SDDMDEEQSR PNTPQLPLSL TTHERHRSSP 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [483-652]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LMDEDEDEAG EQQQPQEAKS DGMNGSVKDE ERQEKSRDEL QDNEKENSNG EDRHLDADAQ  60
   61 MEASSNLNNN HNNSSLHIEQ EVGSTPKRST PKEEDDDLDM DEDEEDNEND ASHLDEFRSP 120
  121 SPDLAGGVVP HKDQLPFPMV PNSMFSQSFM YMSHYIPAFG QAAAGHPHHH 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [653-780]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAAAAAAAGI QPNALMGGGG LNLSSISNEE RRKRNRTFID PVTEVPKLEQ WFAMNTHPSH  60
   61 NLILKYTEDL NTMPYRQKFP RLESKNVQFW FKNRRAKCKR LKMSLYDSNQ CAQLGGLGSF 120
  121 VPKYEERD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.09691
Match: 1fjlA
Description: Paired protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.26183812259792 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.14886080629275 bayes_pls_golite062009
chromatin binding 1.04132983826241 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle