| Protein: | par-1-PA |
| Organism: | Drosophila melanogaster |
| Length: | 938 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for par-1-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
672.0 | [0..1] | [938..1] |
|
Region A: Residues: [1-519] |
1 11 21 31 41 51
| | | | | |
1 MSTAMRTTLQ SVPEALPADS VSNGTASNVA APAAPVSSAT NAVPPLAAVS STTATYATNS 60
61 ISTSSHSVKD QQQQQQQQQH DSANANIVSL PPTTTPVANT NTMMPIVTSS NSATSNSTAA 120
121 TPTPASGAAA TGGVGSVSQG PATVSASAAN TNHSHQHSHQ HHHHVANNMT TDGARLSSNN 180
181 SAVVASSAIN HHHHHTPGSG VAPTVNKNVL STHSAHPSAI KQRTSSAKGS PNMQMRSSAP 240
241 MRWRATEEHI GKYKLIKTIG KGNFAKVKLA KHLPTGKEVA IKIIDKTQLN PGSLQKLFRE 300
301 VRIMKMLDHP NIVKLFQVIE TEKTLYLIME YASGGEVFDY LVLHGRMKEK EARVKFRQIV 360
361 SAVQYCHQKR IIHRDLKAEN LLLDSELNIK IADFGFSNEF TPGSKLDTFC GSPPYAAPEL 420
421 FQGKKYDGPE VDVWSLGVIL YTLVSGSLPF DGSTLRELRE RVLRGKYRIP FYMSTDCENL 480
481 LRKFLVLNPA KRASLETIMG DKWMNMGFEE DELKPYIEP
|
| Detection Method: |  |
| Confidence: | 68.0 |
| Match: | 2h8hA |
| Description: | No description for 2h8hA was found. |
| Term | Confidence | Notes |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.04467222534257 | bayes_pls_golite062009 |
| kinase activity | 4.85903980916957 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.63692708178478 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.26787750561728 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| tubulin binding | 2.18641675163967 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| telethonin binding | 2.01406978272617 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| microtubule binding | 1.88110801192607 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| JUN kinase kinase kinase activity | 1.41172362253967 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 1.3898059094397 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.38496328649031 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.33740973673697 | bayes_pls_golite062009 |
| actin binding | 1.33479685165255 | bayes_pls_golite062009 |
| receptor signaling protein activity | 1.27291233344322 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.2323381312171 | bayes_pls_golite062009 |
| protein binding | 1.22565748038754 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| alpha-actinin binding | 1.13281682085386 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.959360414036299 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| nucleic acid binding | 0.444972929276369 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| signal transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| molecular transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| actin filament binding | 0.2403700250846 | bayes_pls_golite062009 |
| transcription regulator activity | 0.222474717779546 | bayes_pls_golite062009 |
| DNA binding | 0.198054762876122 | bayes_pls_golite062009 |
| transporter activity | 0.187543377461637 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.0556163711947139 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.0413380592707298 | bayes_pls_golite062009 |
| transcription factor activity | 0.026050048647416 | bayes_pls_golite062009 |
| MAP kinase kinase kinase kinase activity | 0.01826424351081 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.00652065412910241 | bayes_pls_golite062009 |
|
Region A: Residues: [520-598] |
1 11 21 31 41 51
| | | | | |
1 KADLADPKRI EALVAMGYNR SEIEASLSQV RYDDVFATYL LLGRKSTDPE SDGSRSGSSL 60
61 SLRNISGNDA GANAGSASV
|
| Detection Method: | |
| Confidence: | 0.974 |
| Match: | 1vegA |
| Description: | Solution Structure of RSGI RUH-012, a UBA Domain from Mouse cDNA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.36429435103114 | bayes_pls_golite062009 |
| nucleic acid binding | 1.20024206233026 | bayes_pls_golite062009 |
| transcription regulator activity | 1.02448431026096 | bayes_pls_golite062009 |
| protein binding | 1.01573863836689 | bayes_pls_golite062009 |
| DNA binding | 0.857155321682303 | bayes_pls_golite062009 |
| small conjugating protein binding | 0.490118840379627 | bayes_pls_golite062009 |
| ubiquitin binding | 0.319972124839967 | bayes_pls_golite062009 |
| catalytic activity | 0.2736776367506 | bayes_pls_golite062009 |
|
Region A: Residues: [599-844] |
1 11 21 31 41 51
| | | | | |
1 QSPTHRGVHR SISASSTKPS RRASSGVGPT NAAATVAAAT GAVGAVNPSN NYNAAGSAAD 60
61 RASVGSNFKR QNTIDSATIK ENTARLAAQN QRPASATQKM LTTADTTLNS PAKPRTATKY 120
121 DPTNGNRTVS GTSGIIPRRS TTLYEKTSST EKTNVIPAET NLFDRLRMAS AVKSSRHFPR 180
181 NVPSRSTFHS GQTRARNNTA LEYSGTSGAS GDSSHPGRMS FFSKLSSRFS KRPTIADEAA 240
241 KPRVLR
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [845-938] |
1 11 21 31 41 51
| | | | | |
1 FTWSMKTTSP LMPDQIMQKI REVLDQNNCD YEQRERFVLW CVHGDPNTDS LVQWEIEVCK 60
61 LPRLSLNGVR FKRISGTSIG FKNIASRIAF DLKL
|
| Detection Method: | |
| Confidence: | 44.045757 |
| Match: | 1ul7A |
| Description: | Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein kinase activity | 4.05475891009228 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 3.7974128326421 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 3.59230737331367 | bayes_pls_golite062009 |
| kinase activity | 3.41737435609334 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 3.2342722637405 | bayes_pls_golite062009 |
| binding | 2.41732321506551 | bayes_pls_golite062009 |
| transferase activity | 2.04713540681686 | bayes_pls_golite062009 |
| ATP binding | 1.44435058039859 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.41005152726625 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.38971642420542 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.16863558166547 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.16859376715941 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.15633908642115 | bayes_pls_golite062009 |
| nucleotide binding | 1.14964488472581 | bayes_pls_golite062009 |
| AMP-activated protein kinase activity | 1.12923456567012 | bayes_pls_golite062009 |
| catalytic activity | 0.836142537655721 | bayes_pls_golite062009 |
| protein binding | 0.704339182896017 | bayes_pls_golite062009 |
| magnesium ion binding | 0.439688030503848 | bayes_pls_golite062009 |
