| Protein: | sdk-PC |
| Organism: | Drosophila melanogaster |
| Length: | 2232 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sdk-PC.
| Description | E-value | Query Range |
Subject Range |
|
|
1465.0 | [0..1] | [2232..1] |
|
Region A: Residues: [1-71] |
1 11 21 31 41 51
| | | | | |
1 MLKSAASSLR RRRPKTTITA TLAIEMPSQP KLASLLAVLV LLCYCDSCFF CYADANLQQQ 60
61 NSIVQQQQLQ A
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [72-162] |
1 11 21 31 41 51
| | | | | |
1 PRFTTHPSSS GSIVSEGSTK ILQCHALGYP QPTYRWLKDG VPVGDFSSSQ FYRFHSTRRE 60
61 DAGSYQCIAR NDAGSIFSEK SDVVVAYMGI F
|
| Detection Method: | |
| Confidence: | 64.69897 |
| Match: | 1cs6A |
| Description: | Axonin-1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [163-645] |
1 11 21 31 41 51
| | | | | |
1 ENTTEGRLTV ISGHPAIFDM PPIESIPVPS VMWQSEDGPL NYDIKYAFTH ANQLIILSAD 60
61 ENDRKGYRAK AINTQLGKEE SSAFVHLNVS GDPYIEVAPE IIVRPQDVKV KVGTGVVELQ 120
121 CIANARPLHE LETLWLKDGL AVETAGVRHT LNDPWNRTLA LLQANSSHSG EYTCQVRLRS 180
181 GGYPAVSASA RLQILEPPLF FTPMRAETFG EFGGQVQLTC DVVGEPTPQV KWFRNAESVD 240
241 AHIESGRYTL NTDNTLVIKK LILDDAAMFQ CLAINEAGEN SASTWLRVKT SAPIMELPPQ 300
301 NVTALDGKDA TISCRAVGSP NPNITWIYNE TQLVDISSRV QILESGDLLI SNIRSVDAGL 360
361 YICVRANEAG SVKGEAYLSV LVRTQIIQPP VDTTVLLGLT ATLQCKVSSD PSVPYNIDWY 420
421 REGQSSTPIS NSQRIGVQAD GQLEIQAVRA SDVGSYACVV TSPGGNETRA ARLSVIELPF 480
481 PPS
|
| Detection Method: | |
| Confidence: | 16.69897 |
| Match: | 2ocwA |
| Description: | No description for 2ocwA was found. |
|
Region A: Residues: [646-749] |
1 11 21 31 41 51
| | | | | |
1 NVKVERLPEP QQRSINVSWT PGFDGNSPIS KFIIQRREVS ELEKFVGPVP DPLLNWITEL 60
61 SNVSADQRWI LLENLKAATV YQFRVSAVNR VGEGSPSEPS NVVE
|
| Detection Method: | |
| Confidence: | 36.69897 |
| Match: | 2nziA |
| Description: | No description for 2nziA was found. |
|
Region A: Residues: [750-858] |
1 11 21 31 41 51
| | | | | |
1 LPQEAPSGPP VGFVGSARSM SEIITQWQPP LEEHRNGQIL GYILRYRLFG YNNVPWSYQN 60
61 ITNEAQRNFL IQELITWKDY IVQIAAYNNM GVGVYTEGSK IKTKEGVPE
|
| Detection Method: | |
| Confidence: | 12.522879 |
| Match: | 2edxA |
| Description: | No description for 2edxA was found. |
|
Region A: Residues: [859-1061] |
1 11 21 31 41 51
| | | | | |
1 APPTNVKVEA INSTAARCRW TPPNPQQING INQGYKIQAW QRRLIDGEWR DIERRMKTVP 60
61 PSLIDPLAEQ TAILGGLEKF TEYNISVLCF TDPGDGVASS QVAVMTMDDV PDEVTGLHFD 120
121 DVSDRSVKVL WAPPRASNGI LTGYTVRYQV KDRPDTLKSF NLTADDTELT VNQLQATTHY 180
181 WFEIVAWTRV GSGIPKTATI QSG
|
| Detection Method: | |
| Confidence: | 22.522879 |
| Match: | 1qg3A |
| Description: | Integin beta-4 subunit |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1062-1160] |
1 11 21 31 41 51
| | | | | |
1 VEPVLPHAPT ALALSNIEAF SVVLQFTPGF DGNSSITKWK VEGQTARNMT WFTICEINDP 60
61 DAETLTVTGL VPFTQYRLRL SASNVVGSSK PSEATKDFQ
|
| Detection Method: | |
| Confidence: | 4.9 |
| Match: | 1lwrA |
| Description: | Neural cell adhesion molecule 1, NCAM |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transmembrane receptor activity | 4.5103765150253 | bayes_pls_golite062009 |
| receptor activity | 4.37793227341148 | bayes_pls_golite062009 |
| ankyrin binding | 4.3701493214749 | bayes_pls_golite062009 |
| cytokine binding | 3.96036354316187 | bayes_pls_golite062009 |
| growth factor binding | 3.72927884588092 | bayes_pls_golite062009 |
| structural constituent of muscle | 3.61132881971932 | bayes_pls_golite062009 |
| cytokine receptor activity | 3.56710042152924 | bayes_pls_golite062009 |
| molecular transducer activity | 3.48919490776358 | bayes_pls_golite062009 |
| signal transducer activity | 3.48919490776358 | bayes_pls_golite062009 |
| protein binding | 3.07386271831775 | bayes_pls_golite062009 |
| binding | 3.01297199434173 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.10516556578644 | bayes_pls_golite062009 |
| interleukin-2 binding | 1.94416903283263 | bayes_pls_golite062009 |
| telethonin binding | 1.75786001683918 | bayes_pls_golite062009 |
| peptide hormone binding | 1.75574680918945 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.70249663997305 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.67752723010524 | bayes_pls_golite062009 |
| axon guidance receptor activity | 1.63462880446774 | bayes_pls_golite062009 |
| polysaccharide binding | 1.56054192646753 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.49286223910051 | bayes_pls_golite062009 |
| protein kinase activity | 1.43845497070856 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.31623717161573 | bayes_pls_golite062009 |
| growth hormone receptor activity | 1.29794577237348 | bayes_pls_golite062009 |
| heparin binding | 1.25921104554864 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 1.19954764493429 | bayes_pls_golite062009 |
| interleukin-6 binding | 1.19954764493429 | bayes_pls_golite062009 |
| receptor binding | 1.17610053739662 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.17433712680111 | bayes_pls_golite062009 |
| actinin binding | 1.15472194906555 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.14375759905113 | bayes_pls_golite062009 |
| kinase activity | 1.1286195376114 | bayes_pls_golite062009 |
| interleukin-11 receptor activity | 1.12006611526405 | bayes_pls_golite062009 |
| interleukin-11 binding | 1.12006611526405 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.857069434693096 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.857069434693096 | bayes_pls_golite062009 |
| peptide binding | 0.758731415132682 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.705756302293137 | bayes_pls_golite062009 |
| cell surface binding | 0.702213571164749 | bayes_pls_golite062009 |
| protein dimerization activity | 0.674567146312744 | bayes_pls_golite062009 |
| collagen binding | 0.647753981851696 | bayes_pls_golite062009 |
| ciliary neurotrophic factor binding | 0.645098074815475 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.578079107783197 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.541677628277769 | bayes_pls_golite062009 |
| nucleic acid binding | 0.532471820485807 | bayes_pls_golite062009 |
| transcription regulator activity | 0.48635527300904 | bayes_pls_golite062009 |
| transcription activator activity | 0.473002127561165 | bayes_pls_golite062009 |
| transferase activity | 0.463609249016931 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.452957099078474 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.437214918174507 | bayes_pls_golite062009 |
| identical protein binding | 0.368517091723107 | bayes_pls_golite062009 |
| DNA binding | 0.319941421296035 | bayes_pls_golite062009 |
| hormone binding | 0.19211161691603 | bayes_pls_golite062009 |
| pattern binding | 0.182490294011655 | bayes_pls_golite062009 |
| transcription factor binding | 0.148740979131497 | bayes_pls_golite062009 |
| growth factor activity | 0.0139937971827004 | bayes_pls_golite062009 |
| integrin binding | 0.013361887492048 | bayes_pls_golite062009 |
|
Region A: Residues: [1161-1275] |
1 11 21 31 41 51
| | | | | |
1 TIQARPKHPP FNVTVRAMSA QQLRVRWIPL QQTEWYGNPR GYNISYKQLV KTPGTIKYVP 60
61 RSVVIEDHTA NSHVLDSLEE WTLYEVKMNA CNDVGCSKES DTAVERTREA VPSYG
|
| Detection Method: | |
| Confidence: | 35.30103 |
| Match: | 1fnfA |
| Description: | FRAGMENT OF HUMAN FIBRONECTIN ENCOMPASSING TYPE-III REPEATS 7 THROUGH 10 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1276-2000] |
1 11 21 31 41 51
| | | | | |
1 PLDVQANATS STTVVVQWGE VPRQHRNGQI DGYKVFYAAA DRGQQVLHKT IPNNATFTTT 60
61 LTELKKYVVY HVQVLAYTRL GNGALSTPPI RVQTFEDTPG VPSNVSFPDV SLTMARIIWD 120
121 VPVDPNGKIL AYQVTYTLNG SAMLNYSREF PPSDRTFRAT ELLPGKYYSF SCTAQTRLGW 180
181 GKIATALVYT TNNRERPQAP SVPQISRSQI QAHQITFSWT PGRDGFAPLR YYTVEMRENE 240
241 GRWQPLPERV DPSLSSFTAV GLRPYMTYQF RIQATNDLGP SAFSRESVIV RTLPAAPAVG 300
301 VGGLKVVPIT TTSVRVQWSA LETALWNGDA STGGYRILYQ QLSDFPTALQ STPKTDVHGI 360
361 NENSVVLSDL QQDRNYEIVV LPFNSQGPGP ATPPAAVYVG EAVPTGEPRA VDAAPISSTE 420
421 VRLLWKPPKQ SMQNGDILGY KIYYLVTYSP QALEPGRKWE EEIEVVSATA TSHSLVFLDK 480
481 FTEYRIQLLA FNPAGDGPRS APITVKTLPG VPSAPLHLRF SDITMQSLEV TWDPPKFLNG 540
541 EILGYLVTYE TTEENEKFSK QVKQKVSNTT LRVQNLEEEV TYTFTVRAQT SVDYGPGISE 600
601 NVTTGPQDGS PVAPRDLILT KTLSSVEMHW INGPSGRGPI LGYLIEAKKR EKGEPSFVYD 660
661 SRWTKIEQTR KGMMQDFTVS YHILMPSTAY TFRVIAYNRY GISFPVYSKD SILTPSKLHL 720
721 EYGYL
|
| Detection Method: | |
| Confidence: | 38.69897 |
| Match: | 2v5yA |
| Description: | No description for 2v5yA was found. |
|
Region A: Residues: [2001-2105] |
1 11 21 31 41 51
| | | | | |
1 QHKPFYRQTW FMVSLAATSI VIIVMVIAVL CVKSKSYKYK QEAQKTLEES MAMSIDERQE 60
61 LALELYRSRH GVGTGTLNSV GTLRSGTLGT LGRKSTSRPP PGVHL
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [2106-2232] |
1 11 21 31 41 51
| | | | | |
1 GKSPPRPSPA SVAYHSDEES LKCYDENPDD SSVTEKPSEV SSSEASQHSE SENESVRSDP 60
61 HSFVNHYANV NDSLRQSWKK TKPVRNYSSY TDSEPEGSAV MSLNGGQIIV NNMARSRAPL 120
121 PGFSSFV
|
| Detection Method: | |
| Confidence: | 3.39794 |
| Match: | 1x5aA |
| Description: | The solution structure of the second fibronectin type III domain of mouse Ephrin type-A receptor 1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transmembrane receptor activity | 4.81256300373074 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| receptor activity | 4.66147271961356 | bayes_pls_golite062009 |
| cytokine binding | 4.43581512268554 | bayes_pls_golite062009 |
| cytokine receptor activity | 4.08668869714207 | bayes_pls_golite062009 |
| growth factor binding | 4.06808996928726 | bayes_pls_golite062009 |
| structural constituent of muscle | 3.84784419485732 | bayes_pls_golite062009 |
| molecular transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| signal transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| interleukin-2 binding | 2.38131482184802 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| prolactin receptor activity | 2.15346920063421 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 2.15011619378442 | bayes_pls_golite062009 |
| peptide hormone binding | 2.12033076929638 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| telethonin binding | 1.93341916149844 | bayes_pls_golite062009 |
| growth hormone receptor activity | 1.71208292022464 | bayes_pls_golite062009 |
| polysaccharide binding | 1.69642470905172 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 1.66250899275539 | bayes_pls_golite062009 |
| interleukin-6 binding | 1.66250899275539 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.6158868405814 | bayes_pls_golite062009 |
| interleukin-11 receptor activity | 1.57103867592521 | bayes_pls_golite062009 |
| interleukin-11 binding | 1.57103867592521 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| heparin binding | 1.40418056272895 | bayes_pls_golite062009 |
| receptor binding | 1.31676259534833 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 1.27120658254426 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 1.27120658254426 | bayes_pls_golite062009 |
| actinin binding | 1.25223034107956 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| ciliary neurotrophic factor binding | 1.02710126648804 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.992216255634359 | bayes_pls_golite062009 |
| peptide binding | 0.92031154055894 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.817385502041609 | bayes_pls_golite062009 |
| cell surface binding | 0.792329562040096 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| collagen binding | 0.688581536921572 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.554350228628563 | bayes_pls_golite062009 |
| transcription activator activity | 0.529736394173061 | bayes_pls_golite062009 |
| nucleic acid binding | 0.522840770355105 | bayes_pls_golite062009 |
| hormone binding | 0.49524185948356 | bayes_pls_golite062009 |
| transcription regulator activity | 0.470959482317512 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.46168925186147 | bayes_pls_golite062009 |
| transferase activity | 0.432850266451294 | bayes_pls_golite062009 |
| DNA binding | 0.310798383307903 | bayes_pls_golite062009 |
| pattern binding | 0.30071837231983 | bayes_pls_golite062009 |
| transcription factor binding | 0.210682741845199 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.0682540643558203 | bayes_pls_golite062009 |
| growth factor activity | 0.0477008672713168 | bayes_pls_golite062009 |
