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View Structure Prediction Details

Protein: nas-4
Organism: Caenorhabditis elegans
Length: 315 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nas-4.

Description E-value Query
Range
Subject
Range
BP10_PARLI - Blastula protease 10 OS=Paracentrotus lividus GN=BP10 PE=2 SV=1
281.0 [0..2] [314..1]

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Predicted Domain #1
Region A:
Residues: [1-79]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMTIQRYSLV FCAIFATCWT ASVVNNKQVI DTSVPQTETT LNDADFHSDL HQRYDLQTLG  60
   61 IKVKDDPTIG NYSEGDILL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.0
Match: 1slmA
Description: CRYSTAL STRUCTURE OF FIBROBLAST STROMELYSIN-1: THE C-TRUNCATED HUMAN PROENZYME
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [80-315]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESPKKFVEEN NKLGRNAIKQ IYRRWPNNEI PYTLSSQYGS YARSVIANAM NEYHTKTCVK  60
   61 FVARDPSKHH DYLWIHPDEG CYSLVGKTGG KQPVSLDSGC IQVGTIVHEL MHAVGFFHEQ 120
  121 SRQDRDSYID VVWQNVMNGA DDQFEKYNLN VISHLDEPYD YASIMHYGPY AFSGSGKKTL 180
  181 VPKKSGSERM GQRVKFSDID VRKINKLYNC PGVSGNNNNN NNNQINSNSI VNHPQV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.0
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.1917763812737 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.85190688399485 bayes_pls_golite062009
metallopeptidase activity 3.22757426039234 bayes_pls_golite062009
endopeptidase activity 2.98133341931091 bayes_pls_golite062009
hydrolase activity 2.78513171530601 bayes_pls_golite062009
metalloendopeptidase activity 2.54952091441017 bayes_pls_golite062009
binding 0.910292205820092 bayes_pls_golite062009
catalytic activity 0.891187593353827 bayes_pls_golite062009
protein binding 0.553658909577001 bayes_pls_golite062009
exopeptidase activity 0.492456025063956 bayes_pls_golite062009
receptor activity 0.332822250208465 bayes_pls_golite062009
transmembrane receptor activity 0.136560284009247 bayes_pls_golite062009
aminopeptidase activity 0.00533877867882504 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle