YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: HACL_ARATH
Organism: Arabidopsis thaliana
Length: 572 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HACL_ARATH.

Description E-value Query
Range
Subject
Range
gi|7436698 - pir||C70341 acetolactate synthase (EC 4.1.3.18) large chain - Aquifex aeolicus
gi|15605942, gi|... - gi|2983101|gb|AAC06706.1| acetolactate synthase large subunit [Aquifex aeolicus VF5], gi|15605942|re...
586.0 [0..13] [571..5]

Back

Predicted Domain #1
Region A:
Residues: [1-572]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADKSETTPP SIDGNVLVAK SLSHLGVTHM FGVVGIPVTS LASRAMALGI RFIAFHNEQS  60
   61 AGYAASAYGY LTGKPGILLT VSGPGCVHGL AGLSNAWVNT WPMVMISGSC DQRDVGRGDF 120
  121 QELDQIEAVK AFSKLSEKAK DVREIPDCVS RVLDRAVSGR PGGCYLDIPT DVLRQKISES 180
  181 EADKLVDEVE RSRKEEPIRG SLRSEIESAV SLLRKAERPL IVFGKGAAYS RAEDELKKLV 240
  241 EITGIPFLPT PMGKGLLPDT HEFSATAARS LAIGKCDVAL VVGARLNWLL HFGESPKWDK 300
  301 DVKFILVDVS EEEIELRKPH LGIVGDAKTV IGLLNREIKD DPFCLGKSNS WVESISKKAK 360
  361 ENGEKMEIQL AKDVVPFNFL TPMRIIRDAI LAVEGPSPVV VSEGANTMDV GRSVLVQKEP 420
  421 RTRLDAGTWG TMGVGLGYCI AAAVASPDRL VVAVEGDSGF GFSAMEVETL VRYNLAVVII 480
  481 VFNNGGVYGG DRRGPEEISG PHKEDPAPTS FVPNAGYHKL IEAFGGKGYI VETPDELKSA 540
  541 LAESFAARKP AVVNVIIDPF AGAESGRLQH KN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 98.0
Match: 2c31A
Description: CRYSTAL STRUCTURE OF OXALYL-COA DECARBOXYLASE IN COMPLEX WITH THE COFACTOR DERIVATIVE THIAMIN-2-THIAZOLONE DIPHOSPHATE AND ADENOSINE DIPHOSPHATE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
acetolactate synthase activity 12.903449876837 bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups 12.3239025230705 bayes_pls_golite062009
pyruvate dehydrogenase activity 5.28857071459273 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 5.21233670052586 bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity 5.08663245333808 bayes_pls_golite062009
transketolase activity 2.50501741089295 bayes_pls_golite062009
catalytic activity 2.25537597692103 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 2.15444163802756 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 1.98546381612935 bayes_pls_golite062009
thiamin pyrophosphate binding 1.87247313698582 bayes_pls_golite062009
oxidoreductase activity 1.85833680148029 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 1.82969293063325 bayes_pls_golite062009
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity 1.65348126142808 bayes_pls_golite062009
deoxyhypusine synthase activity 1.46517585302326 bayes_pls_golite062009
alpha-ketoacid dehydrogenase activity 1.20517690263403 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 1.0611726850452 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 0.982646671777 bayes_pls_golite062009
binding 0.980920092099572 bayes_pls_golite062009
histone deacetylase activity 0.9493052849746 bayes_pls_golite062009
protein deacetylase activity 0.942714095508542 bayes_pls_golite062009
transcription regulator activity 0.872247149132548 bayes_pls_golite062009
NAD-dependent histone deacetylase activity 0.86895852396873 bayes_pls_golite062009
NAD-dependent protein deacetylase activity 0.86895852396873 bayes_pls_golite062009
cation transmembrane transporter activity 0.78591260444574 bayes_pls_golite062009
nucleic acid binding 0.625412573920025 bayes_pls_golite062009
DNA binding 0.56819169389651 bayes_pls_golite062009
hydrolase activity 0.536729211484905 bayes_pls_golite062009
ion transmembrane transporter activity 0.51426028502998 bayes_pls_golite062009
transferase activity 0.413024577830522 bayes_pls_golite062009
deacetylase activity 0.34210759801484 bayes_pls_golite062009
pyruvate decarboxylase activity 0.198062360371269 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.114062221123972 bayes_pls_golite062009
transcription factor binding 0.0144694403853303 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle