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View Structure Prediction Details

Protein: PEP_ARATH
Organism: Arabidopsis thaliana
Length: 495 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEP_ARATH.

Description E-value Query
Range
Subject
Range
gi|1575609 - gi|1575609|gb|AAC50893.1| FUSE binding protein 3 [Homo sapiens]
235.0 [0..21] [483..52]

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Predicted Domain #1
Region A:
Residues: [1-290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAVADSVEN NGSINLPENE NLIPAGFSAA ALLDENSGAF PELNQPDSLA AAETTFPDTN  60
   61 DSAEERWPGW PGDCVFRMIV PVTKVGAIIG RKGDFIKKMC EETRARIKVL DGPVNTPDRI 120
  121 VLISGKEEPE AYMSPAMDAV LRVFRRVSGL PDNDDDDVQN AGSVFSSVRL LVASTQAINL 180
  181 IGKQGSLIKS IVENSGASVR ILSEEETPFY AAQDERIVDL QGEALKILKA LEAIVGHLRR 240
  241 FLVDHTVVPL FEKQYLARVS QTRQEEPLAE SKSSLHTISS NLMEPDFSLL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.39794
Match: 1e3hA
Description: Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.09002897694881 bayes_pls_golite062009
nucleic acid binding 2.55336640491561 bayes_pls_golite062009
RNA binding 2.47373172667773 bayes_pls_golite062009
binding 1.9759530321894 bayes_pls_golite062009
DNA binding 1.83809666640016 bayes_pls_golite062009
structure-specific DNA binding 1.28199205469179 bayes_pls_golite062009
transcription factor activity 1.21526211005888 bayes_pls_golite062009
structural constituent of ribosome 1.05717140831527 bayes_pls_golite062009
transcription termination factor activity 1.01993495617192 bayes_pls_golite062009
single-stranded DNA binding 0.97496043954059 bayes_pls_golite062009
0.966603287421221 bayes_pls_golite062009
sequence-specific DNA binding 0.85691075793641 bayes_pls_golite062009
structural molecule activity 0.734332455050128 bayes_pls_golite062009
ribonuclease activity 0.702449673647117 bayes_pls_golite062009
protein binding 0.523813050066193 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 0.449277083957511 bayes_pls_golite062009
mRNA binding 0.403794675006504 bayes_pls_golite062009
exoribonuclease activity 0.40223812695012 bayes_pls_golite062009
translation regulator activity 0.22908707234671 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.179682348023561 bayes_pls_golite062009
3'-5'-exoribonuclease activity 0.13299060447839 bayes_pls_golite062009
catalytic activity 0.10089766806364 bayes_pls_golite062009
transcription factor binding 0.0560158842173433 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [291-495]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ARREPLFLER DSRVDSRVQP SGVSIYSQDP VLSARHSPGL ARVSSAFVTQ VSQTMQIPFS  60
   61 YAEDIIGVEG ANIAYIRRRS GATITIKESP HPDQITVEIK GTTSQVQTAE QLIQEFIINH 120
  121 KEPVSVSGGY ARIDSGYVPA YPPQLSNRQE PLPSTYMGTE PVQYRPTAYS QLGGPSTYTP 180
  181 TLTGQTYGSE YRPASDVGGY SSYNL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.09691
Match: 2hh2A
Description: No description for 2hh2A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle