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View Structure Prediction Details

Protein: C7102_ARATH
Organism: Arabidopsis thaliana
Length: 499 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for C7102_ARATH.

Description E-value Query
Range
Subject
Range
gi|115496944, gi... - gi|94574282|gb|AAI16042.1| Cytochrome P450, family 2, subfamily C, polypeptide 18 [Bos taurus], gi|1...
372.0 [0..28] [491..20]

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Predicted Domain #1
Region A:
Residues: [1-499]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVFSVSIFAS LAPYLVSALL LFFLIEQLSY LVKKRNLPGP LFVPPIIGNA ISLVRDPTSF  60
   61 WFKQSDTAGT SPGLAANYLI GKFIIYIRDT ELSHQIFSNV RLEAFHPLGH PFGKQLFGDH 120
  121 SLIYLFGEDH KTVRRHLAPN FTPKALSTYS DLQQIVMLRH LRQWEESFSG GTKPVSMRDL 180
  181 VRELNLETSQ TVFVGPYLDK EARNTFCTDY NLFNLGSMAL PINLPGFAFN KARRAVMNLE 240
  241 KTLSVCAGKS KKRMATGEEP TCLIDFWMHA FVTEIESGNP PPLHSEDEAI GGLLFDFLFA 300
  301 AQDASTSSLL WAVTFLESHP KVLSKVREEV AKIWSPQSGH LITADQLAEM KYTRAVAREV 360
  361 VRYRPPATMV PHIATNDFPL TESYTIPKGT IVFPSVFDAS FQGFTEPNRF DPDRFSETRQ 420
  421 EDQVFKRNYL AFGWGAHQCV GQRYALNHLV LFIAMFSSLF DFKRLQSDGC DDIIYCPTIS 480
  481 PKDGCTVFLS KRIVTYPNL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 98.69897
Match: 1pq2A
Description: Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
arachidonic acid monooxygenase activity 6.76823710927794 bayes_pls_golite062009
monooxygenase activity 5.57229509004705 bayes_pls_golite062009
steroid hydroxylase activity 5.04794778387361 bayes_pls_golite062009
arachidonic acid epoxygenase activity 4.80764258881036 bayes_pls_golite062009
retinoic acid 4-hydroxylase activity 3.76307535769621 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3.68151610133025 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 3.47932403870887 bayes_pls_golite062009
retinoic acid binding 3.04897926497756 bayes_pls_golite062009
sterol 14-demethylase activity 2.94610675710811 bayes_pls_golite062009
retinoid binding 2.60220937953757 bayes_pls_golite062009
demethylase activity 2.49146495571604 bayes_pls_golite062009
isoprenoid binding 2.47826119804163 bayes_pls_golite062009
oxysterol 7-alpha-hydroxylase activity 2.36480328243514 bayes_pls_golite062009
vitamin D 25-hydroxylase activity 1.65825585934141 bayes_pls_golite062009
vitamin D3 25-hydroxylase activity 1.65825585934141 bayes_pls_golite062009
fatty acid (omega-1)-hydroxylase activity 1.65569090470706 bayes_pls_golite062009
electron carrier activity 1.48516712188486 bayes_pls_golite062009
testosterone 6-beta-hydroxylase activity 1.4661447981611 bayes_pls_golite062009
binding 1.2866152532988 bayes_pls_golite062009
vitamin D 24-hydroxylase activity 1.03699542179837 bayes_pls_golite062009
oxidoreductase activity 0.959942871652667 bayes_pls_golite062009
catalytic activity 0.608111453189583 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 0.33710488712754 bayes_pls_golite062009
oxygen binding 0.3117502273138 bayes_pls_golite062009
1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity 0.169431271735966 bayes_pls_golite062009
25-hydroxycholecalciferol-24-hydroxylase activity 0.167565425989292 bayes_pls_golite062009
arachidonic acid 11,12-epoxygenase activity 0.0888154993183798 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle